Search Results - "Fischer, Audrey E."

Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization by Kolawole, Abimbola O, Li, Ming, Xia, Chunsheng, Fischer, Audrey E, Giacobbi, Nicholas S, Rippinger, Christine M, Proescher, Jody B G, Wu, Susan K, Bessling, Seneca L, Gamez, Monica, Yu, Chenchen, Zhang, Rebecca, Mehoke, Thomas S, Pipas, James M, Wolfe, Joshua T, Lin, Jeffrey S, Feldman, Andrew B, Smith, Thomas J, Wobus, Christiane E

“…New human norovirus strains emerge every 2 to 3 years, partly due to mutations in the viral capsid that allow escape from antibody neutralization and herd…”
Get full text

A high-throughput drop microfluidic system for virus culture and analysis by Fischer, Audrey E., Wu, Susan K., Proescher, Jody B.G., Rotem, Assaf, Chang, Connie B., Zhang, Huidan, Tao, Ye, Mehoke, Thomas S., Thielen, Peter M., Kolawole, Abimbola O., Smith, Thomas J., Wobus, Christiane E., Weitz, David A., Lin, Jeffrey S., Feldman, Andrew B., Wolfe, Joshua T.

“…•A microfluidic system has been developed for viral culture.•Viral infection and replication within microdrops is similar to bulk conditions.•This system may…”
Get full text

Evolution on the Biophysical Fitness Landscape of an RNA Virus by Rotem, Assaf, Serohijos, Adrian W R, Chang, Connie B, Wolfe, Joshua T, Fischer, Audrey E, Mehoke, Thomas S, Zhang, Huidan, Tao, Ye, Lloyd Ung, W, Choi, Jeong-Mo, Rodrigues, João V, Kolawole, Abimbola O, Koehler, Stephan A, Wu, Susan, Thielen, Peter M, Cui, Naiwen, Demirev, Plamen A, Giacobbi, Nicholas S, Julian, Timothy R, Schwab, Kellogg, Lin, Jeffrey S, Smith, Thomas J, Pipas, James M, Wobus, Christiane E, Feldman, Andrew B, Weitz, David A, Shakhnovich, Eugene I

“…Viral evolutionary pathways are determined by the fitness landscape, which maps viral genotype to fitness. However, a quantitative description of the landscape…”
Get full text

Site Saturation Mutant Viruses Evolve Neutralizing Antibody Resistance in a Microfluidic Cell Culture System by Evans, Jared D., Fischer, Audrey E., Wu, Susan, Thielen, Peter M., Mehoke, Thomas S., Sivakumar, Ashok, Wolfe, Joshua T.

Get full text