Search Results - "Fischer, Andrew H"

Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei by Hatch, Emily M., Fischer, Andrew H., Deerinck, Thomas J., Hetzer, Martin W.

“…During mitotic exit, missegregated chromosomes can recruit their own nuclear envelope (NE) to form micronuclei (MN). MN have reduced functioning compared to…”
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The diagnostic pathology of the nuclear envelope in human cancers by Fischer, Andrew H

“…Cancer is still diagnosed on the basis of altered tissue and cellular morphology. The criteria that pathologists use for diagnosis include many morphologically…”
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The Utility of MYB Immunohistochemistry (IHC) in Fine Needle Aspiration (FNA) Diagnosis of Adenoid Cystic Carcinoma (AdCC) by Sun, Tong, Akalin, Ali, Dresser, Karen, Fischer, Andrew H., Zuo, Tao

“…Differentiating adenoid cystic carcinoma (AdCC) from other basaloid neoplasm in a fine needle aspiration (FNA) sample can be challenging. Activation of MYB in…”
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Causes of false-negative for high-grade urothelial carcinoma in urine cytology by Lee, Paul J., Owens, Christopher L., Lithgow, Marie Y., Jiang, Zhong, Fischer, Andrew H.

“…Introduction The Paris System for classifying urine cytology emphasizes identification of high‐grade urothelial carcinoma (HGUC). The causes of false‐negative…”
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Melanoma Spheroid Formation Involves Laminin-Associated Vasculogenic Mimicry by Larson, Allison R, Lee, Chung-Wei, Lezcano, Cecilia, Zhan, Qian, Huang, John, Fischer, Andrew H, Murphy, George F

“…Melanoma is a tumor where virulence is conferred on transition from flat (radial) to three-dimensional (tumorigenic) growth. Virulence of tumorigenic growth is…”
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Performance differences between conventional smears and liquid-based preparations of thyroid fine-needle aspiration samples: analysis of 47,076 responses in the College of American Pathologists Interlaboratory Comparison Program in Non-Gynecologic Cytology by Fischer, Andrew H, Clayton, Amy C, Bentz, Joel S, Wasserman, Patricia G, Henry, Michael R, Souers, Rhona J, Moriarty, Ann T

“…Controversy exists about whether thyroid fine-needle aspirates (FNAs) should be processed with conventional smears or liquid-based preparations (LBPs). To…”
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Expression of a novel oncofetal mRNA-binding protein IMP3 in endometrial carcinomas: diagnostic significance and clinicopathologic correlations by Li, Cuizhen, Zota, Victor, Woda, Bruce A, Rock, Kenneth L, Fraire, Armando E, Jiang, Zhong, Lu, Di, Xu, Bo, Dresser, Karen, Lutman, Christopher V, Fischer, Andrew H

“…Insulin-like growth factor-II mRNA-binding protein 3 (IMP3) is a newly identified oncofetal mRNA-binding protein that is involved in embryogenesis and…”
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Lenvatinib Targets PDGFR-β Pericytes and Inhibits Synergy With Thyroid Carcinoma Cells: Novel Translational Insights by Iesato, Asumi, Li, Stephanie, Roti, Giovanni, Hacker, Michele R, Fischer, Andrew H, Nucera, Carmelo

“…Pericyte populations abundantly express tyrosine kinases (eg, platelet-derived growth factor receptor-β [PDGFR-β]) and impact therapeutic response. Lenvatinib…”
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Use of IMP3 in Identification of Carcinoma in Fine Needle Aspiration Biopsies of Pancreas by Yantiss, Rhonda K., Cosar, Ediz, Fischer, Andrew H.

“…To evaluate insulin-like growth factor-II mRNA binding protein 3 (IMP3), which is an oncofetal RNA-binding protein expressed in pancreatic carcinomas and…”
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Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model by Duquette, Mark, Sadow, Peter M, Husain, Amjad, Sims, Jennifer N, Antonello, Zeus A, Fischer, Andrew H, Song, Chen, Castellanos-Rizaldos, Elena, Makrigiorgos, G Mike, Kurebayashi, Junichi, Nose, Vania, Van Hummelen, Paul, Bronson, Roderick T, Vinco, Michelle, Giordano, Thomas J, Dias-Santagata, Dora, Pandolfi, Pier Paolo, Nucera, Carmelo

“…BRAF(V600E) mutation exerts an essential oncogenic function in many tumors, including papillary thyroid carcinoma (PTC). Although BRAF(V600E) inhibitors are…”
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Nuclear structure in cancer cells by Zink, Daniele, Fischer, Andrew H, Nickerson, Jeffrey A

“…Nuclear architecture - the spatial arrangement of chromosomes and other nuclear components - provides a framework for organizing and regulating the diverse…”
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Molecular aspects of diagnostic nucleolar and nuclear envelope changes in prostate cancer by Fischer, Andrew H., Bardarov Jr, Svetoslav, Jiang, Zhong

“…Prostate cancer is still diagnosed by pathologists based on subjective assessment of altered cell and tissue structure. The cellular‐level structural changes…”
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An Automatable Method for Determining Adequacy of Thyroid Fine-Needle Aspiration Samples by Schmolze, Daniel B, Fischer, Andrew H

“…Thyroid nodules are a common clinical problem. Cytologic evaluation via fine-needle aspiration is often employed in the diagnostic workup, and rapid on-site…”
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Significance of cytopathologist's review of Pap tests screened as negative for intraepithelial lesion or malignancy that are positive for high-risk human papillomavirus by Walavalkar, Vighnesh, MD, Fischer, Andrew H., MD, Owens, Christopher L., MD

“…Introduction Cytopathologist's review of Papanicolaou tests (PTs) screened by cytotechnologists as negative for intraepithelial lesion or malignancy (NILM)…”
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New quantitative data on cell blocks by Fischer, Andrew H.

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Fluorescence Polarization Imaging of Methylene Blue Facilitates Quantitative Detection of Thyroid Cancer in Single Cells by Jermain, Peter R, Fischer, Andrew H, Joseph, Lija, Muzikansky, Alona, Yaroslavsky, Anna N

“…Diagnostic accuracy of the standard of care fine-needle aspiration cytology (FNAC) remains a significant problem in thyroid oncology. Therefore, a robust and…”
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Utility of liquid-based cytologic examination of distal esophageal brushings in the management of Barrett esophagus: a prospective study of 45 cases by Walavalkar, Vighnesh, MD, Patwardhan, Rashmi V., MD, Owens, Christopher L., MD, Lithgow, Marie, MD, Wang, Xiaofei, MD, Akalin, Ali, MD, Nompleggi, Dominic J., MD, PhD, Zivny, Jaroslav, MD, Wassef, Wahid, MD, Marshall, Christopher, MD, Levey, John, MD, Walter, Otto, MD, Fischer, Andrew H., MD

“…Introduction The goal of Barrett esophagus surveillance is to identify high-grade dysplasia (HGD) for eradication. Surveillance programs currently rely on…”
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Cell blocks of breast FNAs frequently allow diagnosis of invasion or histological classification of proliferative changes by Istvanic, Smiljana, Fischer, Andrew H., Banner, Barbara F., Eaton, Donna M., Larkin, Anne C., Khan, Ashraf

“…Two major limitations of breast fine needle aspiration (FNA) compared with core needle biopsies (CNB) are the inability to determine whether a cancer is…”
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Confocal laser endomicroscopy: a primer for pathologists by Paull, Peter E, Hyatt, Benjamin J, Wassef, Wahid, Fischer, Andrew H

“…The advent of new endoscopic optical techniques is likely to change pathologists' role in diagnosis. To describe how confocal laser endomicroscopy (CLE) works,…”
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Diagnostic value of a comprehensive, urothelial carcinoma–specific next‐generation sequencing panel in urine cytology and bladder tumor specimens by Sun, Tong, Hutchinson, Lloyd, Tomaszewicz, Keith, Caporelli, Mandi‐Lee, Meng, Xiuling, McCauley, Kathleen, Fischer, Andrew H., Cosar, Ediz F., Cornejo, Kristine M.

“…Background Urine cytology can reliably diagnose high‐grade urothelial carcinoma (HGUC) but not low‐grade urothelial carcinoma (LGUC), and a more sensitive test…”
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