Search Results - "Firth, A. E."

ICTV Virus Taxonomy Profile: Iflaviridae by Valles, S M, Chen, Y, Firth, A E, Guérin, D M A, Hashimoto, Y, Herrero, S, de Miranda, J R, Ryabov, E, Ictv Report Consortium

“…Iflaviridae is a family of small non-enveloped viruses with monopartite, positive-stranded RNA genomes of approximately 9-11 kilobases. Viruses of all…”
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An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response by Jagger, B. W., Wise, H. M., Kash, J. C., Walters, K.-A., Wills, N. M., Xiao, Y.-L., Dunfee, R. L., Schwartzman, L. M., Ozinsky, A., Bell, G. L., Dalton, R. M., Lo, A., Efstathiou, S., Atkins, J. F., Firth, A. E., Taubenberger, J. K., Digard, P.

“…Influenza A virus (IAV) infection leads to variable and imperfectly understood pathogenicity. We report that segment 3 of the virus contains a second open…”
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ICTV Virus Taxonomy Profile: Dicistroviridae by Valles, S M, Chen, Y, Firth, A E, Guérin, D M A, Hashimoto, Y, Herrero, S, de Miranda, J R, Ryabov, E, Ictv Report Consortium

“…Dicistroviridae is a family of small non-enveloped viruses with monopartite, linear, positive-sense RNA genomes of approximately 8-10 kb. Viruses of all…”
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Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction by Firth, A. E., Jagger, B. W., Wise, H. M., Nelson, C. C., Parsawar, K., Wills, N. M., Napthine, S., Taubenberger, J. K., Digard, P., Atkins, J. F.

“…Programmed ribosomal frameshifting is used in the expression of many virus genes and some cellular genes. In eukaryotic systems, the most well-characterized…”
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User‐friendly algorithms for estimating completeness and diversity in randomized protein‐encoding libraries by Patrick, Wayne M., Firth, Andrew E., Blackburn, Jonathan M.

“…Directed evolution of proteins depends on the production of molecular diversity by random mutagenesis. While a number of methods have been developed for…”
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The Las Campanas Infrared Survey: Early-Type Galaxy Progenitors beyond z = 1 by McCarthy, P. J, Carlberg, R. G, Chen, H.-W, Marzke, R. O, Firth, A. E, Ellis, R. S, Persson, S. E, McMahon, R. G, Lahav, O, Wilson, J, Martini, P, Abraham, R. G, Sabbey, C. N, Oemler, A, Murphy, D. C, Somerville, R. S, Beckett, M. G, Lewis, J. R, MacKay, C. D

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Nonstructural proteins nsp2TF and nsp2N of porcine reproductive and respiratory syndrome virus (PRRSV) play important roles in suppressing host innate immune responses by Li, Y., Shang, P., Shyu, D., Carrillo, C., Naraghi-Arani, P., Jaing, Crystal J., Renukaradhya, G.J., Firth, A.E., Snijder, E.J., Fang, Y.

“…Recently, we identified a unique -2/-1 ribosomal frameshift mechanism in PRRSV, which yields two truncated forms of nonstructural protein (nsp) 2 variants,…”
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The Las Campanas Infrared Survey – II. Photometric redshifts, comparison with models and clustering evolution by Firth, A. E., Somerville, R. S., McMahon, R. G., Lahav, O., Ellis, R. S., Sabbey, C. N., McCarthy, P. J., Chen, H.-W., Marzke, R. O., Wilson, J., Abraham, R. G., Beckett, M. G., Carlberg, R. G., Lewis, J. R., Mackay, C. D., Murphy, D. C., Oemler, A. E., Persson, S. E.

“…The Las Campanas Infrared (LCIR) Survey, using the Cambridge Infra-Red Survey Instrument (CIRSI), reaches H∼21 over nearly 1 deg2. In this paper we present…”
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Geochemistry and mineralogy of platinum group element mineralization in the River Valley Intrusion, Ontario, Canada; a model for early-stage sulfur saturation and multistage emplacement and the implications for "contact-type" Ni-Cu-PGE sulfide mineralization by Holwell, David A, Keays, Reid R, Firth, Emily A, Findlay, Jon

“…The River Valley intrusion within the approximately 2.48 Ga East Bull Lake intrusive suite in Ontario, Canada, is an example of a mafic igneous intrusion with…”
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The Las Campanas Infrared Survey. III. The H-Band Imaging Survey and the Near-Infrared and Optical Photometric Catalogs by Chen, Hsiao-Wen, McCarthy, P. J, Marzke, R. O, Wilson, J, Carlberg, R. G, Firth, A. E, Persson, S. E, Sabbey, C. N, Lewis, J. R, McMahon, R. G, Lahav, O, Ellis, R. S, Martini, P, Abraham, R. G, Oemler, A, Murphy, D. C, Somerville, R. S, Beckett, M. G, Mackay, C. D

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Estimating photometric redshifts with artificial neural networks by Firth, Andrew E., Lahav, Ofer, Somerville, Rachel S.

“…A new approach to estimating photometric redshifts — using artificial neural networks (ANNs) — is investigated. Unlike the standard template-fitting…”
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GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries by Firth, Andrew E, Patrick, Wayne M

“…There are many methods for introducing random mutations into nucleic acid sequences. Previously, we described a suite of programmes for estimating the…”
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Infrared constraints on the dark mass concentration observed in the cluster Abell 1942 by Gray, Meghan E., Ellis, Richard S., Lewis, James R., McMahon, Richard G., Firth, Andrew E.

“…We present a deep H-band image of the region in the vicinity of the cluster Abell 1942 containing the puzzling dark matter concentration detected in an optical…”
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A Pilot Study of Bacterial Genes with Disrupted ORFs Reveals a Surprising Profusion of Protein Sequence Recoding Mediated by Ribosomal Frameshifting and Transcriptional Realignment by Sharma, Virag, Firth, Andrew E., Antonov, Ivan, Fayet, Olivier, Atkins, John F., Borodovsky, Mark, Baranov, Pavel V.

“…Bacterial genome annotations contain a number of coding sequences (CDSs) that, in spite of reading frame disruptions, encode a single continuous polypeptide…”
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Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria by Remes, Cristina, Khawaja, Anas, Pearce, Sarah F, Dinan, Adam M, Gopalakrishna, Shreekara, Cipullo, Miriam, Kyriakidis, Vasileios, Zhang, Jingdian, Dopico, Xaquin Castro, Yukhnovets, Olessya, Atanassov, Ilian, Firth, Andrew E, Cooperman, Barry, Rorbach, Joanna

“…The synthesis of mitochondrial OXPHOS complexes is central to cellular metabolism, yet many molecular details of mitochondrial translation remain elusive. It…”
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C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis by Gopalakrishna, Shreekara, Pearce, Sarah F, Dinan, Adam M, Schober, Florian A, Cipullo, Miriam, Spåhr, Henrik, Khawaja, Anas, Maffezzini, Camilla, Freyer, Christoph, Wredenberg, Anna, Atanassov, Ilian, Firth, Andrew E, Rorbach, Joanna

“…In all biological systems, RNAs are associated with RNA-binding proteins (RBPs), forming complexes that control gene regulatory mechanisms, from RNA synthesis…”
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Maturation of selected human mitochondrial tRNAs requires deadenylation by Pearce, Sarah F, Rorbach, Joanna, Van Haute, Lindsey, D'Souza, Aaron R, Rebelo-Guiomar, Pedro, Powell, Christopher A, Brierley, Ian, Firth, Andrew E, Minczuk, Michal

“…Human mitochondria contain a genome (mtDNA) that encodes essential subunits of the oxidative phosphorylation system. Expression of mtDNA entails multi-step…”
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Pulmonary Tumours in Urethane-Treated Mice: Failure to Demonstrate an Underlying Infective Aetiology by FIRTH, E A, ROE, F J

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Statistics of protein library construction by Firth, Andrew E., Patrick, Wayne M.

“…We have investigated the statistics associated with constructing and sampling large protein-encoding libraries. Using fairly simple statistics we have written…”
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Detecting overlapping coding sequences in virus genomes by Firth, Andrew E, Brown, Chris M

“…Detecting new coding sequences (CDSs) in viral genomes can be difficult for several reasons. The typically compact genomes often contain a number of…”
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