Search Results - "Firstova, V. V."
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Next-Generation Antibiotics, Bacteriophage Endolysins, and Nanomaterials for Combating Pathogens
Published in Biochemistry (Moscow) (01-11-2020)“…This review presents various strategies to fight causative agents of infectious diseases. Species-specific programmable RNA-containing antibiotics open up new…”
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2
Identification of Immunological Correlates of Protection during Development of Specific Immunity to Francisella tularensis
Published in Problemy osobo opasnyh infekcij (01-10-2024)“…Live tularemia vaccine is one of the most effective bacterial vaccines. However, it also has high residual virulence for laboratory animals and may cause…”
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3
Humoral immune response to shiga toxin 2 (Stx2) in children with escherichiosis with hemolytic-uremic syndrome
Published in Infekt͡s︡ii͡a︡ i immunitet (28-07-2024)“…Shiga toxin-producing Escherichia coli (STEC) causes acute intestinal infections and also causes acute renal failure, especially in children. Shiga toxins…”
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4
Monoclonal Antibodies Capable of Inhibiting the Interaction of the Receptor Binding Domain of SARS-CoV-2 Virus with the Angiotensin-Converting Receptor 2 of Human Cells
Published in Problemy osobo opasnyh infekcij (01-10-2024)“…The aim of the work was to evaluate the ability of monoclonal antibodies to inhibit the interaction of the receptor binding domain (RBD) in S protein of…”
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5
Evaluation of the long-term memory T cell in mice after immunization with a live tularemia vaccine
Published in Medit͡s︡inskai͡a︡ immunologii͡a (01-06-2023)“…The vaccine strain F. tularensis 15 NIIEG induces long-lived cell-mediated immunity but exhibits a certain reactogenicity and genetic instability. Progress in…”
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Antibiotic Adjuvant 4-Hexylresorcinol Enhances the Efficiency of Antituberculosis Drugs
Published in Bulletin of experimental biology and medicine (01-02-2024)“…We studied the possibility of using 4-hexylresorcinol to increase the efficiency of anti-mycobacterial chemotherapy. In an in vitro experiment,…”
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Stress-Tolerant Dormant Bacterial Forms: Biological and Ultrastructural Properties of Moraxella catarrhalis and Kocuria rhizophila
Published in Bulletin of experimental biology and medicine (01-01-2024)“…Dormant forms of causative agents of healthcare-acquired infections Moraxella catarrhalis and Kocuria rhizophila have been obtained. Dormant forms cells…”
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Current understanding of Bacillus anthracis toxin molecules organization and approaches for blocking their cytotoxic action
Published in Infekt͡s︡ii͡a︡ i immunitet (01-02-2020)“…Here, we review the data on mechanisms inhibiting cytotoxic effect of anthrax toxin on the immune system cells. Various disease forms, immunopathogenesis and…”
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Is It Possible to Create Antimicrobial Peptides Based on the Amyloidogenic Sequence of Ribosomal S1 Protein of P. aeruginosa?
Published in International journal of molecular sciences (10-09-2021)“…The development and testing of new antimicrobial peptides (AMPs) represent an important milestone toward the development of new antimicrobial drugs that can…”
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10
Selection of Candidate Monoclonal Antibodies for Therapy of Botulinum Toxin Type A Intoxications
Published in Toxins (01-07-2024)“…Botulism is one of the most serious food intoxications, manifesting as prolonged paralytic conditions. This disease is usually the result of the consumption of…”
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Optimization of Electrofusion Parameters for Producing Hybridomas Synthesizing Human Monoclonal Antibodies
Published in Applied biochemistry and microbiology (01-12-2022)“…Monoclonal antibodies are an established treatment for many illnesses, including cancer, toxicity and infectious diseases. The goal of this work was to…”
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Binary Biofilms of Staphylococcus aureus 209P and Kytococcus schroeteri H01: Dualistic Role of Kytococci and Cell Adhesion Alterations in the Presence of the A-Type Natriuretic Peptide
Published in Microbiology (New York) (01-10-2022)“…— Investigation of the interactions between Staphylococcus aureus 209P and Kytococcus schroeteri H01 in binary biofilms revealed the sensitivity of these…”
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Trace Element Assemblages of Pseudomorphic Iron Oxyhydroxides of the Pobeda-1 Hydrothermal Field, 17°08.7′ N, Mid-Atlantic Ridge: The Development of a Halmyrolysis Model from LA-ICP-MS Data
Published in Minerals (Basel) (01-01-2023)“…Halmyrolysis, as one of the global processes of alteration of seafloor hydrothermal sediments, needs to be recognized in terms of mineral and trace element…”
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14
Characterization of the C6D7-RBD Human Monoclonal Antibody Specific to the SARS-CoV-2 S Protein Receptor-Binding Domain
Published in Actanaturae (01-01-2023)“…The new coronavirus infection COVID-19 is an acute viral disease that affects primarily the upper respiratory tract. The etiological agent of COVID-19 is the…”
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Characterization of Immunogenic and Protective Properties of the Modified Variants of the Strain Francisella tularensis 15 NIIEG
Published in Problemy osobo opasnyh infekcij (22-10-2020)“…Francisella tularensis is an intracellular bacterium that causes tularemia. Progress in creating a safe and effective vaccine for the prevention of tularemia…”
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16
Antibacterial and Immunomodulating Activity of Silver Nanoparticles on Mice Experimental Tuberculosis Model
Published in Applied biochemistry and microbiology (01-03-2020)“…The antibacterial activity of silver nanoparticles with a size of 43.6 ± 10.7 nm against strain Mycobacterium tuberculosis H37Rv was studied in vitro (the…”
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Mechanism of Action of Monoclonal Antibodies That Block the Activity of the Lethal Toxin of Bacillus Anthracis
Published in Actanaturae (01-10-2021)“…Neutralization of the lethal toxin of Bacillus anthracis is an important topic of both fundamental medicine and practical health care, regarding the fight…”
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Molecular Lipopolysaccharide Di-Vaccine Protects from Shiga-Toxin Producing Epidemic Strains of Escherichia coli O157:H7 and O104:H4
Published in Vaccines (Basel) (01-11-2022)“…Background: Shiga toxin-producing Escherichia coli (STEC) O157:H7 and O104:H4 strains are important causative agents of food-borne diseases such as hemorrhagic…”
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Detecting specific memory t and b cells in volunteers annually revaccinated with live anthrax vaccine
Published in Infekt͡s︡ii͡a︡ i immunitet (14-11-2019)“…Currently, live anthrax vaccine has been used for vaccine prophylaxis in Russia and neighbor countries for seve ral decades, but precise mechanism of…”
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20
Effect of 4-Hexylresorcinol on the Efficiency of Antibiotic Treatment of Experimental Sepsis Caused by Antibiotic-Resistant Klebsiella pneumoniae Strain in Mice
Published in Bulletin of experimental biology and medicine (01-08-2021)“…High efficiency of a combined preparation including synergistic polymyxin B and 4-hexylresorcinol was shown for treatment of experimental sepsis caused by an…”
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