Search Results - "Firouzabadi, Negar"

A focused review on technologies, mechanisms, safety, and efficacy of available COVID-19 vaccines by Ghasemiyeh, Parisa, Mohammadi-Samani, Soliman, Firouzabadi, Negar, Dehshahri, Ali, Vazin, Afsaneh

“…[Display omitted] •Different platforms of vaccines used in COVID-19 prevention.•The immunologic mechanisms, safety, and efficacy of available COVID-19…”
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Metformin and insulin-resistant related diseases: Emphasis on the role of microRNAs by Alimoradi, Nahid, Firouzabadi, Negar, Fatehi, Reihaneh

“…Metformin is one of the most prescribed drugs in type II diabetes (T2DM) which has recently found new applications in the prevention and treatment of various…”
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The renin-angiotensin-aldosterone system (RAAS) signaling pathways and cancer: foes versus allies by Hassani, Bahareh, Attar, Zeinab, Firouzabadi, Negar

“…Abstract The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental roles in cancer biology which influences cell growth,…”
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Metformin attenuates symptoms of osteoarthritis: role of genetic diversity of Bcl2 and CXCL16 in OA by Alimoradi, Nahid, Tahami, Mohammad, Firouzabadi, Negar, Haem, Elham, Ramezani, Amin

“…This study aimed to evaluate the effectiveness of metformin versus placebo in overweight patients with knee osteoarthritis (OA). In addition, to assess the…”
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SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease by Alimoradi, Nahid, Sharqi, Moein, Firouzabadi, Dena, Sadeghi, Mohammad Moein, Moezzi, Mohammad Iman, Firouzabadi, Negar

“…COVID-19 and the renin-angiotensin system (RAS) are linked by angiotensin-converting enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a…”
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ncRNAs and polyphenols: new therapeutic strategies for hypertension by Shirazi-Tehrani, Elham, Chamasemani, Alireza, Firouzabadi, Negar, Mousaei, Marzieh

“…Polyphenols have gained significant attention in protecting several chronic diseases, such as cardiovascular diseases (CVDs). Accumulating evidence indicates…”
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How metformin affects various malignancies by means of microRNAs: a brief review by Alimoradi, Nahid, Firouzabadi, Negar, Fatehi, Reihaneh

“…Metformin known as the first-line orally prescribed drug for lowering blood glucose in type II diabetes (T2DM) has recently found various therapeutic…”
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The effect of size, morphology and surface properties of mesoporous silica nanoparticles on pharmacokinetic aspects and potential toxicity concerns by Niroumand, Uranous, Firouzabadi, Negar, Goshtasbi, Ghazal, Hassani, Bahareh, Ghasemiyeh, Parisa, Mohammadi-Samani, Soliman

“…Mesoporous silica nanoparticles (MSNs) are considered as suitable delivery vehicles considering their unique characteristics. Various physicochemical…”
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Interleukin-33 and Soluble ST2 as Potential Biomarkers of Cancer in Opium Users: A Nested Case-Control Study by Firouzabadi, Negar, Javdani, Kimia, Dehshahri, Ali

“…Background: Opium abuse is one of the social hazards in the Middle Eastern countries. Opium consumption attributes to various malignancies. However, the exact…”
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Combination of metformin and gallic acid induced autophagy and apoptosis in human breast cancer cells by Haghshenas, Marziyeh, Firouzabadi, Negar, Akbarizadeh, Amin, Rashedinia, Marzieh

“…Background and purpose: Breast cancer is the most common type of cancer and one of the major causes of death among women. Many reports propose gallic acid as a…”
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Impact of vitamin D receptor gene polymorphisms (TaqI and BsmI) on the incidence and severity of coronary artery disease: a report from southern Iran by Akhlaghi, Boshra, Firouzabadi, Negar, Foroughinia, Farzaneh, Nikparvar, Marzieh, Dehghani, Pouyan

“…The association of vitamin D level and vitamin D receptor (VDR) gene polymorphisms with the prevalence of coronary artery disease (CAD) has been evaluated in…”
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Modulation of ACE2/Ang1-7/Mas and ACE/AngII/AT1 axes affects anticancer properties of sertraline in MCF-7 breast cancer cells by Fatehi, Reihaneh, Nouraei, Mohammad, Panahiyan, Morteza, Rashedinia, Marzieh, Firouzabadi, Negar

“…The renin–angiotensin system (RAS) is best known for playing a major role in maintaining the physiology of the cardiovascular system. Dysregulation of the RAS…”
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A longitudinal item response model for Aberrant Behavior Checklist (ABC) data from children with autism by Haem, Elham, Doostfatemeh, Marziyeh, Firouzabadi, Negar, Ghazanfari, Nima, Karlsson, Mats O.

“…This manuscript aims to present the first item response theory (IRT) model within a pharmacometric framework to characterize the longitudinal changes of…”
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Genetic Variants of Angiotensin-Converting Enzyme Are Linked to Autism: A Case-Control Study by Firouzabadi, Negar, Ghazanfari, Nima, Alavi Shoushtari, Ali, Erfani, Nasrallah, Fathi, Farshid, Bazrafkan, Mozhdeh, Bahramali, Ehsan

“…Autism is a disease of complex nature with a significant genetic component. The importance of renin-angiotensin system (RAS) elements in cognition and behavior…”
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DRD3 Ser9Gly Polymorphism and Its Influence on Risperidone Response in Autistic Children by Firouzabadi, Negar, Nazariat, Anna, Zomorrodian, Kamiar

“…Autism, a neuropsychiatric illness, is a complex ailment of mainly indefinite cause. Although precise pathophysiological mechanism is unclear but the role of…”
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Association of human platelet alloantigens encoding gene polymorphisms with the risk of Coronary artery disease in Iranian patients by Malakootikhah, Farideh, Naghavi, Hossein, Firouzabadi, Negar, Maadani, Mohsen, Shafiei, Massoumeh, Tajik, Nader

“…Coronary artery disease (CAD) is characterized by narrowing/ blockade of coronary arteries that is mainly caused by atherosclerotic plaques. Considering the…”
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Beta Adrenoceptor Polymorphism and Clinical Response to Sertraline in Major Depressive Patients by Firouzabadi, Negar, Raeesi, Roshanak, Zomorrodian, Kamiar, Bahramali, Ehsan, Yavarian, Ilnaz

“…The adrenoceptor family, as one of the main contributors in regulating the noradrenergic system, has been studied in involvement of depression and its…”
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FKBP5 blockade may provide a new horizon for the treatment of stress‐associated disorders: An in‐silico study by Asadi‐Pooya, Ali A., Malekpour, Mahdi, Zamiri, Bardia, Kashkooli, Mohammad, Firouzabadi, Negar

“…Objective We searched for, from the FDA (Food and Drug Administration‐USA)‐approved drugs, inhibitors of FKBP5 with tolerable adverse effect profiles (eg, mild…”
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Polymorphism of glucocorticoid receptor gene ( rs41423247 ) in functional seizures (psychogenic nonepileptic seizures/attacks) by Firouzabadi, Negar, Asadi‐Pooya, Ali A., Alimoradi, Nahid, Simani, Leila, Asadollahi, Marjan

“…Abstract Objective We investigated the association between the glucocorticoid receptor (GR) gene, also known as the nuclear receptor subfamily 3, group C,…”
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Potential role of FKBP5 single‐nucleotide polymorphisms in functional seizures by Asadi‐Pooya, Ali A., Simani, Leila, Asadollahi, Marjan, Rashidi, Fatemeh Sadat, Ahmadipour, Ehsan, Alavi, Afagh, Roozbeh, Mehrdad, Akbari, Nayyereh, Firouzabadi, Negar

“…Objective We investigated the associations between FKBP5 single‐nucleotide polymorphisms (SNPs) and functional seizures (FS). Methods Seventy patients with FS,…”
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