Search Results - "Firer, Danielle"

Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis by Boiarsky, Rebecca, Haradhvala, Nicholas J., Alberge, Jean-Baptiste, Sklavenitis-Pistofidis, Romanos, Mouhieddine, Tarek H., Zavidij, Oksana, Shih, Ming-Chieh, Firer, Danielle, Miller, Mendy, El-Khoury, Habib, Anand, Shankara K., Aguet, François, Sontag, David, Ghobrial, Irene M., Getz, Gad

“…Multiple myeloma is a plasma cell malignancy almost always preceded by precursor conditions, but low tumor burden of these early stages has hindered the study…”
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Single-Cell RNA-Sequencing of 370 Bone Marrow and Peripheral Blood Immune Cell Samples from Patients with MGUS and Smoldering Multiple Myeloma Reveal Significant Immune Dysregulation at the MGUS Stage, and Novel Interactions between Tumor and Immune Cells by Sklavenitis-Pistofidis, Romanos, Wu, Ting, Rahmat, Mahshid, Konishi, Yoshinobu, Lightbody, Elizabeth D., Timonian, Michael, Tsuji, Junko, Firer, Danielle T., Haradhvala, Nicholas J., Soekojo, Cinnie Yentia, Wang, Xiyue, Heilpern-Mallory, Daniel, Aguet, François, Getz, Gad, Ghobrial, Irene

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Single Cell Characterization of Myeloma and Its Precursor Conditions Reveals Transcriptional Signatures of Early Tumorigenesis by Boiarsky, Rebecca, Haradhvala, Nicholas, Sklavenitis-Pistofidis, Romanos, Mouhieddine, Tarek H, Alberge, Jean-Baptiste, Zavidij, Oksana, Firer, Danielle, Anand, Shankara, El-Khoury, Habib, Aguet, François, Sontag, David, Ghobrial, Irene M., Getz, Gad

“…Our understanding of disease progression in multiple myeloma (MM) and its precursor conditions, monoclonal gammopathy of undetermined significance (MGUS) and…”
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P-101 Single-cell RNA sequencing of 1.3 million plasma cells from patients with MGUS and SMM by Sklavenitis-Pistofidis, Romanos, Lightbody, Elizabeth, Tsuji, Junko, Agius, Michael, Rahmat, Mahshid, Konishi, Yoshinobu, Wu, Ting, Aranha, Michelle, Firer, Danielle, Haradhvala, Nicholas, Getz, Gad, Ghobrial, Irene

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P-411 Large-scale single-cell dissection of immune dysregulation in patients with monoclonal gammopathies by Sklavenitis-Pistofidis, Romanos, Wu, Ting, Lightbody, Elizabeth, Konishi, Yoshinobu, Rahmat, Mahshid, Timonian, Michael, Tsuji, Junko, Aranha, Michelle, Firer, Danielle, Haradhvala, Nicholas, Heilpern-Mallory, Daniel, Getz, Gad, Ghobrial, Irene

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Single-Cell RNA Sequencing of Circulating Tumor Cells in Precursor Myeloma Patients Reveals Mechanisms of Disease Dissemination by Lightbody, Elizabeth D., Sklavenitis-Pistofidis, Romanos, Firer, Danielle T., Tsuji, Junko, Agius, Mike P., Dutta, Ankit K., Wu, Ting, Barr, Hadley, Kim, Sungjae, Coorens, Tim, Alberge, Jean-Baptiste, Aranha, Michelle P., Haradhvala, Nicholas J, Kham Su, Nang, Boehner, Cody J., Walsh, Kelly, Rahmat, Mahshid, Konishi, Yoshinobu, Hevenor, Laura, Towle, Katherine, Horowitz, Erica M., Perry, Jacqueline, Fleming, Grace, El-Khoury, Habib, Vinyard, Michael, Cowan, Annie, Auclair, Daniel, Ready, John E., Marinac, Catherine R., Getz, Gad, Ghobrial, Irene M.

“…Introduction Multiple Myeloma (MM) is preceded by the precursors Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Multiple Myeloma…”
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Single-Cell RNA-Sequencing of 245 Tumor Samples from Patients with MGUS and Smoldering Multiple Myeloma Reveals Novel Insights into Malignant Plasma Cell Biology by Tsuji, Junko, Lightbody, Elizabeth D., Sklavenitis-Pistofidis, Romanos, Agius, Michael P., Rahmat, Mahshid, Barr, Hadley, Konishi, Yoshinobu, Dutta, Ankit K., Su, Nang Kham, Boehner, Cody J., Firer, Danielle T., Wu, Ting, Aranha, Michelle P., Hevenor, Laura, Horowitz, Erica, Perry, Jacqueline, Aguet, François, Haradhvala, Nicholas J., Boiarsky, Rebecca, Getz, Gad, Ghobrial, Irene

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The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR by Huang, Jessie, Lam, Hong, Koziol-White, Cynthia, Limjunyawong, Nathachit, Kim, Donghwa, Kim, Nicholas, Karmacharya, Nikhil, Rajkumar, Premraj, Firer, Danielle, Dalesio, Nicholas M., Jude, Joseph, Kurten, Richard C., Pluznick, Jennifer L., Deshpande, Deepak A., Penn, Raymond B., Liggett, Stephen B., Panettieri, Reynold A., Dong, Xinzhong, An, Steven S.

“…The recent discovery of sensory (tastant and odorant) G protein-coupled receptors on the smooth muscle of human bronchi suggests unappreciated therapeutic…”
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Single-Cell RNA Sequencing of Rare Circulating Tumor Cells in Precursor Myeloma Patients Reveals Molecular Underpinnings of Tumor Cell Circulation by Lightbody, Elizabeth D., Firer, Danielle T., Sklavenitis-Pistofidis, Romanos, Tsuji, Junko, Agius, Michael P., Dutta, Ankit K., Wu, Ting, Barr, Hadley, Rahmat, Mahshid, Konishi, Yoshinobu, Aranha, Michelle P., Vinyard, Michael, Alberge, Jean-Baptiste, Kham Su, Nang, Boehner, Cody J., Hevenor, Laura, El-Khoury, Habib, Towle, Katherine, Cea-Curry, Christian J., Horowitz, Erica, Perry, Jacqueline, Cowan, Anna, Justis, Anna V., Auclair, Daniel, Marinac, Catherine R., Getz, Gad, Ghobrial, Irene

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OA-40 SWIFT-Seq: Single-Cell RNA Sequencing of Circulating Tumor Cells as a Comprehensive Clinically Applicable Liquid Biopsy Test for Patients With Multiple Myeloma and Its Precursor Conditions by Lightbody, Elizabeth, Sklavenitis-Pistofidis, Romanos, Wu, Ting, Tsuji, Junko, Firer, Danielle, Agius, Michael, Dutta, Ankit, Barr, Hadley, Kim, Sungjae, Alberge, Jean-Baptiste, Nersesian, Sarah, Coorens, Tim, Haradhvala, Nicholas, Su, Nang Kham, Boehner, Cody J., Aranha, Michelle, Rahmat, Mahshid, Konishi, Yoshinobu, Hevenor, Laura, Towle, Katherine, Horowitz, Erica, Perry, Jacqueline, Marinac, Catherine R., Getz, Gad, Ghobrial, Irene

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P-097 Single-cell RNA sequencing of circulating tumor cells in precursor myeloma patients reveals early mechanisms of disease dissemination by Lightbody, Elizabeth, Firer, Danielle, Sklavenitis-Pistofidis, Romanos, Tsuji, Junko, Agius, Michael, Dutta, Ankit, Wu, Ting, Barr, Hadley, Rahmat, Mahshid, Konishi, Yoshinobu, Aranha, Michelle, Alberge, Jean-Baptiste, Su, Nang Kham, Boehner, Cody, Hevenor, Laura, El-Khoury, Habib, Towle, Katherine, Cea-Curry, Christian, Horowitz, Erica, Perry, Jacqueline, Cowan, Anna, Auclair, Daniel, Marinac, Catherine, Getz, Gad, Ghobrial, Irene

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Abstract 641: Single-cell RNA sequencing of rare circulating tumor cells in precursor myeloma patients reveals molecular underpinnings of tumor cell circulation by Lightbody, Elizabeth D., Firer, Danielle T., Sklavenitis-Pistofidis, Romanos, Agius, Michael, Dutta, Ankit K., Aranha, Michelle, Alberge, Jean-Baptiste, Hevenor, Laura, Su, Nang Kham, Boehner, Cody, Horowitz, Erica, Perry, Jacqueline, Cowan, Anna, Barr, Hadley, Justis, Anna, Auclair, Daniel, Marinac, Catherine R., Getz, Gad, Ghobrial, Irene

“…Abstract Background: Multiple Myeloma (MM) is a hematological malignancy characterized by abnormal proliferation of terminally differentiated plasma cells…”
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