Search Results - "Fiori, Mariana C"

Polymer-encased nanodiscs with improved buffer compatibility by Fiori, Mariana C., Jiang, Yunjiang, Altenberg, Guillermo A., Liang, Hongjun

“…Styrene-maleic acid copolymers allow for solubilization and reconstitution of membrane proteins into nanodiscs. These polymer-encased nanodiscs are promising…”
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Permeation of Calcium through Purified Connexin 26 Hemichannels by Fiori, Mariana C., Figueroa, Vania, Zoghbi, Maria E., Saéz, Juan C., Reuss, Luis, Altenberg, Guillermo A.

“…Gap junction channels communicate the cytoplasms of two cells and are formed by head to head association of two hemichannels, one from each of the cells. Gap…”
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Extracellular Cysteines Are Critical to Form Functional Cx46 Hemichannels by Fernández-Olivares, Ainoa, Durán-Jara, Eduardo, Verdugo, Daniel A, Fiori, Mariana C, Altenberg, Guillermo A, Stehberg, Jimmy, Alfaro, Iván, Calderón, Juan Francisco, Retamal, Mauricio A

“…Connexin (Cxs) hemichannels participate in several physiological and pathological processes, but the molecular mechanisms that control their gating remain…”
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Expression in Sf9 insect cells, purification and functional reconstitution of the human proton-coupled folate transporter (PCFT, SLC46A1) by Date, Swapneeta S, Fiori, Mariana C, Altenberg, Guillermo A, Jansen, Michaela

“…The proton-coupled folate transporter (PCFT) provides an essential uptake route for the vitamin folic acid (B9) in mammals. In addition, it is currently of…”
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Polymer-Encased Nanodiscs and Polymer Nanodiscs: New Platforms for Membrane Protein Research and Applications by Chen, Angela, Majdinasab, Elleana J., Fiori, Mariana C., Liang, Hongjun, Altenberg, Guillermo A.

“…Membrane proteins (MPs) are essential to many organisms’ major functions. They are notorious for being difficult to isolate and study, and mimicking native…”
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Inhibition by Commercial Aminoglycosides of Human Connexin Hemichannels Expressed in Bacteria by Fiori, Mariana C, Krishnan, Srinivasan, Kjellgren, Abbey, Cuello, Luis G, Altenberg, Guillermo A

“…In addition to gap junctional channels that mediate cell-to-cell communication, connexins form hemichannels that are present at the plasma membrane. Since…”
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Functional analysis and regulation of purified connexin hemichannels by Fiori, Mariana C, Reuss, Luis, Cuello, Luis G, Altenberg, Guillermo A

“…Gap-junction channels (GJCs) are aqueous channels that communicate adjacent cells. They are formed by head-to-head association of two hemichannels (HCs), one…”
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Functional hemichannels formed by human connexin 26 expressed in bacteria by Fiori, Mariana C, Krishnan, Srinivasan, Cortes, D Marien, Retamal, Mauricio A, Reuss, Luis, Altenberg, Guillermo A, Cuello, Luis G

“…Gap-junction channels (GJCs) communicate the cytoplasm of adjacent cells and are formed by head-to-head association of two hemichannels (HCs), one from each of…”
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Purification, Reconstitution, and Functional Analysis of Connexin Hemichannels by Fiori, Mariana C, Altenberg, Guillermo A

“…Connexins are the proteins that form the gap junction channels that are essential for cell-to-cell communication. These channels are formed by head-to-head…”
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Extraction and reconstitution of membrane proteins into lipid nanodiscs encased by zwitterionic styrene-maleic amide copolymers by Fiori, Mariana C., Zheng, Wan, Kamilar, Elizabeth, Simiyu, Geuel, Altenberg, Guillermo A., Liang, Hongjun

“…Membrane proteins can be reconstituted in polymer-encased nanodiscs for studies under near-physiological conditions and in the absence of detergents, but…”
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Nanodisc-associated acetylcholinesterase as a novel model system of physiological relevant membrane-bound cholinesterases. Inhibition by phenolic compounds by Salazar, Paula Belén, Dupuy, Fernando Gabriel, Fiori, Mariana C., Stanfield, Samantha M., McCord, Jon, Altenberg, Guillermo A., Minahk, Carlos Javier

“…Acetylcholinesterase (AChE) plays a pivotal role in the cholinergic system, and its inhibition is sought after in a wide range of applications, from insect…”
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Functional and structural comparison of the ABC exporter MsbA studied in detergent and reconstituted in nanodiscs by Arana, Maite R., Fiori, Mariana C., Altenberg, Guillermo A.

“…Purified membrane proteins are most frequently studied solubilized in detergent, but the properties of detergent micelles are very different from those of…”
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4-Hydroxynonenal induces Cx46 hemichannel inhibition through its carbonylation by Retamal, Mauricio A., Fiori, Mariana C., Fernandez-Olivares, Ainoa, Linsambarth, Sergio, Peña, Francisca, Quintana, Daisy, Stehberg, Jimmy, Altenberg, Guillermo A.

“…Hemichannels formed by connexins mediate the exchange of ions and signaling molecules between the cytoplasm and the extracellular milieu. Under physiological…”
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Astroglial gliotransmitters released via Cx43 hemichannels regulate NMDAR‐dependent transmission and short‐term fear memory in the basolateral amygdala by Linsambarth, Sergio, Carvajal, Francisco J., Moraga‐Amaro, Rodrigo, Mendez, Luis, Tamburini, Giovanni, Jimenez, Ivanka, Verdugo, Daniel Antonio, Gómez, Gonzalo I., Jury, Nur, Martínez, Pablo, Zundert, Brigitte, Varela‐Nallar, Lorena, Retamal, Mauricio A., Martin, Claire, Altenberg, Guillermo A., Fiori, Mariana C., Cerpa, Waldo, Orellana, Juan A., Stehberg, Jimmy

“…Astrocytes release gliotransmitters via connexin 43 (Cx43) hemichannels into neighboring synapses, which can modulate synaptic activity and are necessary for…”
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Polymer Nanodiscs: Discoidal Amphiphilic Block Copolymer Membranes as a New Platform for Membrane Proteins by Fiori, Mariana C., Jiang, Yunjiang, Zheng, Wan, Anzaldua, Miguel, Borgnia, Mario J., Altenberg, Guillermo A., Liang, Hongjun

“…Lipid nanodiscs are playing increasingly important roles in studies of the structure and function of membrane proteins. Development of lipid nanodiscs as a…”
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Amphiphilic aminoglycosides with increased selectivity for inhibition of connexin 43 (Cx43) hemichannels by Subedi, Yagya P., Kjellgren, Abbey, Roberts, Paul, Montgomery, Heath, Thackeray, Noah, Fiori, Mariana C., Altenberg, Guillermo A., Chang, Cheng-Wei T.

“…Gap junction channels formed by the association of connexin hemichannels play a crucial role in intercellular communication. Connexin 43 (Cx43) is expressed in…”
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Carbon Monoxide (CO) Is a Novel Inhibitor of Connexin Hemichannels by León-Paravic, Carmen G., Figueroa, Vania A., Guzmán, Diego J., Valderrama, Carlos F., Vallejos, Antonio A., Fiori, Mariana C., Altenberg, Guillermo A., Reuss, Luis, Retamal, Mauricio A.

“…Hemichannels (HCs) are hexamers of connexins that can form gap-junction channels at points of cell contacts or “free HCs” at non-contacting regions. HCs are…”
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Functional Chimeras of GLIC Obtained by Adding the Intracellular Domain of Anion- and Cation-Conducting Cys-Loop Receptors by Mnatsakanyan, Nelli, Nishtala, Sita Nirupama, Pandhare, Akash, Fiori, Mariana C, Goyal, Raman, Pauwels, Jonathan E, Navetta, Andrew F, Ahrorov, Afzal, Jansen, Michaela

“…Pentameric ligand-gated ion channels (pLGICs), also called Cys-loop receptors in eukaryotic superfamily members, play diverse roles in neurotransmission and…”
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Inhibition of Connexin Hemichannels by New Amphiphilic Aminoglycosides without Antibiotic Activity by AlFindee, Madher N., Subedi, Yagya P., Fiori, Mariana C., Krishnan, Srinivasan, Kjellgren, Abbey, Altenberg, Guillermo A., Chang, Cheng-Wei T.

“…Connexins hemichannels (HCs) from adjacent cells form gap junctional channels that mediate cell-to-cell communication. Abnormal opening of “free” undocked HCs…”
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Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness by Dalamon, Viviana, Fiori, Mariana C., Figueroa, Vania A., Oliva, Carolina A., del Rio, Rodrigo, Gonzalez, Wendy, Canan, Jonathan, Elgoyhen, Ana B., Altenberg, Guillermo A., Retamal, Mauricio A.

“…Gap-junction channels (GJCs) are formed by head-to-head association of two hemichannels (HCs, connexin hexamers). HCs and GJCs are permeable to ions and…”
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