Search Results - "Fioretti, C."

Narrating positive versus negative memories of illness: does narrating influence the emotional tone of memories? by Fioretti, C., Smorti, A.

“…Psychoncological studies have recognised a reduced autobiographical memory in cancer patients, furthermore cognitive studies have found that narrative is an…”
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Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease by Romani, Luigina, Puccetti, Paolo, Fallarino, Francesca, De Luca, Antonella, Montagnoli, Claudia, D'Angelo, Carmen, Zelante, Teresa, Vacca, Carmine, Bistoni, Francesco, Fioretti, Maria C, Grohmann, Ursula, Segal, Brahm H

“…Half a century ago, chronic granulomatous disease (CGD) was first described as a disease fatally affecting the ability of children to survive infections…”
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Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation by Grohmann, Ursula, Nicoletti, Ferdinando, Volpi, Claudia, Bruno, Valeria, Puccetti, Paolo, Fioretti, Maria C, Busceti, Carla, Vacca, Carmine, Di Marco, Roberto, Fallarino, Francesca, Battaglia, Giuseppe, Fazio, Francesco, Bicciato, Silvio, Notartomaso, Serena

“…Excessive glutamate seen in multiple sclerosis leads to excitotoxicity and neuronal dysfunction. Fallarino et al . find that the clinical signs and…”
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SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis by Orabona, Ciriana, Pallotta, Maria T, Volpi, Claudia, Fallarino, Francesca, Vacca, Carmine, Bianchi, Roberta, Belladonna, Maria L, Fioretti, Maria C, Grohmann, Ursula, Puccetti, Paolo

“…Despite their common ability to activate intracellular signaling through CD80/CD86 molecules, cytotoxic T lymphocyte antigen 4 (CTLA-4)-Ig and CD28-Ig bias the…”
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Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy by Bianchi, Roberta, Grohmann, Ursula, Belladonna, Maria L, Nocentini, Giuseppe, Riccardi, Carlo, Romani, Luigina, Volpi, Claudia, Bistoni, Francesco, Puccetti, Paolo, Fioretti, Maria C, Ayroldi, Emira, Orabona, Ciriana, Vacca, Carmine, Fallarino, Francesca, Bozza, Silvia, Boon, Louis

“…Glucocorticoid-induced tumor necrosis factor receptor (GITR) on T cells and its natural ligand, GITRL, on accessory cells contribute to the control of immune…”
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IDO Mediates TLR9-Driven Protection from Experimental Autoimmune Diabetes by Fallarino, Francesca, Volpi, Claudia, Zelante, Teresa, Vacca, Carmine, Calvitti, Mario, Fioretti, Maria C, Puccetti, Paolo, Romani, Luigina, Grohmann, Ursula

“…Originally predicated on the recognition of an increasing prevalence of allergy, the hygiene hypothesis was later found to accommodate the contrasting…”
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Vitamin D supplementation at different doses affects the vagal component of the baroreceptor reflex and the Bezold-Jarisch reflex in eutrophic rats by Fioretti, Alexandre C., Dsouki, Nuha A., do Vale, Barbara, de Carvalho, Rodrigo P., Dias, Daniel P. M., Venancio, Daniel P., Fonseca, Fernando L. A., Sato, Monica A.

“…Vitamin D has been used to prevent several diseases. The 1,25 (OH) 2D3, the active form of vitamin D (VitD), participates in calcium metabolism, and has direct…”
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A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice by Grohmann, Ursula, Fallarino, Francesca, Bianchi, Roberta, Orabona, Ciriana, Vacca, Carmine, Fioretti, Maria C, Puccetti, Paolo

“…The predisposition of nonobese diabetic (NOD) mice to develop autoimmunity reflects deficiencies in both peripheral and central tolerance. Several defects have…”
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Kynurenine Pathway Enzymes in Dendritic Cells Initiate Tolerogenesis in the Absence of Functional IDO by Belladonna, Maria L, Grohmann, Ursula, Guidetti, Paolo, Volpi, Claudia, Bianchi, Roberta, Fioretti, Maria C, Schwarcz, Robert, Fallarino, Francesca, Puccetti, Paolo

“…Dendritic cell (DC) tryptophan catabolism has emerged in recent years as a major mechanism of peripheral tolerance. However, there are features of this…”
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T cell apoptosis by tryptophan catabolism by Fallarino, F, Grohmann, U, Vacca, C, Bianchi, R, Orabona, C, Spreca, A, Fioretti, M C, Puccetti, P

“…Indoleamine 2,3-dioxygenase (IDO) is a tryptophan-catabolizing enzyme that, expressed by different cell types, has regulatory effects on T cells resulting from…”
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CTLA-4-Ig regulates tryptophan catabolism in vivo by Grohmann, Ursula, Orabona, Ciriana, Fallarino, Francesca, Vacca, Carmine, Calcinaro, Filippo, Falorni, Alberto, Candeloro, Paola, Belladonna, Maria L, Bianchi, Roberta, Fioretti, Maria C, Puccetti, Paolo

“…Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) plays a critical role in peripheral tolerance. However, regulatory pathways initiated by the interactions…”
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Functional Plasticity of Dendritic Cell Subsets as Mediated by CD40 Versus B7 Activation by Grohmann, Ursula, Bianchi, Roberta, Orabona, Ciriana, Fallarino, Francesca, Vacca, Carmine, Micheletti, Alessandra, Fioretti, Maria C, Puccetti, Paolo

“…Murine dendritic cells (DCs) can present Ag in an immunogenic or tolerogenic fashion, the distinction depending on either the occurrence of specialized DC…”
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CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice by Fallarino, Francesca, Bianchi, Roberta, Orabona, Ciriana, Vacca, Carmine, Belladonna, Maria L, Fioretti, Maria C, Serreze, David V, Grohmann, Ursula, Puccetti, Paolo

“…Prediabetes and diabetes in nonobese diabetic (NOD) mice have been targeted by a variety of immunotherapies, including the use of a soluble form of cytotoxic T…”
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CD40 Ligation Ablates the Tolerogenic Potential of Lymphoid Dendritic Cells by Grohmann, Ursula, Fallarino, Francesca, Silla, Silvia, Bianchi, Roberta, Belladonna, Maria L, Vacca, Carmine, Micheletti, Alessandra, Fioretti, Maria C, Puccetti, Paolo

“…The outcome of dendritic cell (DC) presentation of P815AB, a tolerogenic tumor/self peptide, depends on a balance between the respective immunogenic and…”
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IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production by Grohmann, Ursula, Belladonna, Maria L, Bianchi, Roberta, Orabona, Ciriana, Ayroldi, Emira, Fioretti, Maria C, Puccetti, Paolo

“…We analyzed the expression of an IL-12 receptor by fresh dendritic cells (DC) and a DC line. Using RT-PCR, RNAse protection, and electrophoretic mobility shift…”
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Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells by Fallarino, Francesca, Vacca, Carmine, Orabona, Ciriana, Belladonna, Maria L., Bianchi, Roberta, Marshall, Brendan, Keskin, Derin B., Mellor, Andrew L., Fioretti, Maria C., Grohmann, Ursula, Puccetti, Paolo

“…Immunoregulatory antigen-presenting cells (APC) play an important role in maintaining T cell homeostasis and self-tolerance. In particular, recent evidence…”
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T cell apoptosis by kynurenines by Fallarino, Francesca, Grohmann, Ursula, Vacca, Carmine, Orabona, Ciriana, Spreca, Antonio, Fioretti, Maria C, Puccetti, Paolo

“…Indoleamine 2,3-dioxygenase (IDO) is a tryptophan-catabolizing enzyme that, expressed by different cell types, has regulatory effects on T cells resulting from…”
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Positive regulatory role of IL-12 in macrophages and modulation by IFN-gamma by Grohmann, U, Belladonna, M L, Vacca, Carmine, Bianchi, R, Fallarino, F, Orabona, C, Fioretti, M C, Puccetti, P

“…Similar to myeloid dendritic cells, murine macrophages and macrophage cell lines were found to express a surface receptor for IL-12. As a result, peritoneal…”
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Th1 and Th2 Cell Clones to a Poorly Immunogenic Tumor Antigen Initiate CD8+ T Cell-Dependent Tumor Eradication In Vivo by Fallarino, Francesca, Grohmann, Ursula, Bianchi, Roberta, Vacca, Carmine, Fioretti, Maria C, Puccetti, Paolo

“…Although CD8(+) T cells play a central role as immune effectors, CD4(+) T cells act to control the activation and persistence of the CD8(+) T cell response in…”
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Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12 by Orabona, Ciriana, Tomasello, Elena, Fallarino, Francesca, Bianchi, Roberta, Volpi, Claudia, Bellocchio, Silvia, Romani, Luigina, Fioretti, Maria C., Vivier, Eric, Puccetti, Paolo, Grohmann, Ursula

“…DAP12 is an immunoreceptor tyrosine‐based activation motif‐bearing membrane adapter molecule expressed by different cell types. Although several receptors…”
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