Search Results - "Fiorenza, M. T."
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Altered localization and functionality of TAR DNA Binding Protein 43 (TDP-43) in niemann- pick disease type C
Published in Acta neuropathologica communications (18-05-2016)“…Niemann-Pick type C (NPC) disease is a lysosomal storage disorder characterized by the occurrence of visceral and neurological symptoms. At present, the…”
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TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia
Published in Cell death & disease (01-01-2016)“…Chronic lymphocytic leukemia (CLL) is a B-cell malignancy with a mature phenotype. In spite of its relatively indolent nature, no radical cure is as yet…”
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A marked paucity of granule cells in the developing cerebellum of the Npc1−/− mouse is corrected by a single injection of hydroxypropyl-β-cyclodextrin
Published in Neurobiology of disease (01-10-2014)“…Abstract In this study we show that postnatal development of cerebellar granule neurons (GNs) is defective in Npc1−/− mice. Compared to age-matched wild-type…”
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Strain‐specific proportion of the two isoforms of the dopamine D2 receptor in the mouse striatum: associated neural and behavioral phenotypes
Published in Genes, brain and behavior (01-10-2010)“…Genetic variability in the proportion of the two alternative dopamine D2 receptor (D2R) mRNA splice variants, D2R‐long (D2L) and D2R‐short (D2S), influence…”
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TCL1 promotes blastomere proliferation through nuclear transfer, but not direct phosphorylation, of AKT PKB in early mouse embryos
Published in Cell death and differentiation (01-02-2008)Get full text
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Quantitative RT-PCR amplification of RNA in single mouse oocytes and preimplantation embryos
Published in BioTechniques (01-04-1998)“…We describe a simple whole-cell method for quantitative reverse transcription (RT) PCR amplification of RNA that consistently allows the analysis of trace…”
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Hyperthermia specifically inhibits bivalent chromosome disjunction in maturing mouse oocytes
Published in Biology of reproduction (01-04-1992)“…The effect of hyperthermia on mammalian oocyte maturation was studied by allowing preovulatory mouse oocytes to mature spontaneously for 17 h in vitro under…”
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Developmental regulation of heat-shock response in mouse oogenesis: Identification of differentially responsive oocyte classes during Graafian follicle development
Published in Developmental biology (01-04-1991)“…The response to heat (hs response) of dictyate mouse oocytes at various differentiation stages was analyzed in vitro, by determining patterns of oocyte…”
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TCL1 Participates in Early Embryonic Development and Is Overexpressed in Human Seminomas
Published in Proceedings of the National Academy of Sciences - PNAS (03-09-2002)“…Overexpression of the TCL1 oncogene has been shown to play a causative role in T cell leukemias of humans and mice. The characterization of Tcl1-deficient mice…”
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A developmentally regulated GAGA box-binding factor and Sp1 are required for transcription of the hsp70.1 gene at the onset of mouse zygotic genome activation
Published in Development (Cambridge) (01-04-2000)“…We have investigated the onset of zygotic genome transcription in early two-cell mouse embryos by analyzing the regulation of hsp70.1, one of the first genes…”
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Early Transcriptional Activation of the Hsp70.1 Gene by Osmotic Stress in One-Cell Embryos of the Mouse
Published in Biology of reproduction (01-06-2004)“…In fertilized mouse eggs, de novo transcription of embryonic genes is first observed during the S phase of the one-cell stage. This transcription, however, is…”
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Complex expression of murine heat shock transcription factors
Published in Nucleic acids research (11-02-1995)“…A central step in the transcriptional activation of heat shock genes Is the binding of the heat shock factor (HSF) to upstream heat shock elements (HSEs). In…”
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Growing Dictyate Oocytes, but Not Early Preimplantation Embryos, of the Mouse Display High Levels of DNA Homologous Recombination by Single-Strand Annealing and Lack DNA Nonhomologous End Joining
Published in Developmental biology (01-05-2001)“…We have investigated the ability of growing dictyate oocytes and early preimplantation embryos of the mouse to process extrachromosomal DNA molecules with free…”
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Expression screening for Lhx3 downstream genes identifies Thg-1pit as a novel mouse gene involved in pituitary development
Published in Gene (31-10-2001)“…Thg-1pit, a novel mouse gene, was detected in a screen for genes that are differentially expressed in the developing pituitary of wild-type and Lhx3 null…”
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Developmental Activation of an Episomic hsp70 Gene Promoter in Two-Cell Mouse Embryos by Transcription Factor Sp1
Published in Nucleic acids research (01-04-1997)“…To investigate the control of zygotic genome expression in two-cell mouse embryos, we studied transcription factors required for transient expression of…”
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Molecular cloning and expression analysis of MPPα-2, a novel mouse transcript detected in a differential screen of pituitary libraries
Published in Biochimica et biophysica acta (19-08-2002)“…We identified a novel isoform transcript, MPPα-2, of the mouse Mg 2+-dependent protein phosphatase (MPP) alpha gene. The amino acid sequence encoded by MPPα-2…”
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THG-1pit moves to nucleus at the onset of cerebellar granule neurons apoptosis
Published in Molecular and cellular neuroscience (01-02-2009)“…Thg-1pit (Tsc22d4), a murine gene belonging to the TGF-β1-stimulated clone 22 domain (TSC22D) family, is expressed in developing and adult cerebellar granule…”
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Hedgehog Antagonist RENKCTD11 Regulates Proliferation and Apoptosis of Developing Granule Cell Progenitors
Published in The Journal of neuroscience (07-09-2005)“…During the early development of the cerebellum, a burst of granule cell progenitor (GCP) proliferation occurs in the outer external granule layer (EGL), which…”
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Enhancement of mouse sperm motility by the PI3-kinase inhibitor LY294002 does not result in toxic effects on preimplantation embryo development
Published in Human reproduction (Oxford) (01-12-2005)“…BACKGROUND: A reduced number of progressively motile sperm (as may occur in cases of asthenozoospermia or when cryopreserved spermatozoa are used for…”
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