Search Results - "Fiorella, M"
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Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial
Published in Lancet neurology (2013)“…Summary Background Patients with advanced Parkinson's disease often have rapid swings between mobility and immobility, and many respond unsatisfactorily to…”
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Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides
Published in Nature communications (16-02-2021)“…In the cell, DNA is arranged into highly-organised and topologically-constrained (supercoiled) structures. It remains unclear how this supercoiling affects the…”
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Retigabine, a potassium channel opener, restores thalamocortical neuron functionality in a murine model of autoimmune encephalomyelitis
Published in Brain, behavior, and immunity (01-11-2024)“…•Induction of a cortical inflammatory lesion affects the excitability of ipsilateral thalamic neurons in the EAE model of MS.•Kv7.3 channels regulate the…”
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4
Ferulic Acid Improves Cognitive Skills Through the Activation of the Heme Oxygenase System in the Rat
Published in Molecular neurobiology (01-02-2018)“…Over the last years, many studies reported on the antioxidant effects of ferulic acid (FA) in preclinical models of dementia through the activation of the heme…”
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A Large‐Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands
Published in Movement disorders (01-09-2020)“…Background The most common genetic risk factor for Parkinson's disease known is a damaging variant in the GBA1 gene. The entire GBA1 gene has rarely been…”
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Directional steering: A novel approach to deep brain stimulation
Published in Neurology (23-09-2014)“…OBJECTIVE:The aim of this study was to investigate whether directional steering through a novel 32-contact electrode is safe and can modulate the thresholds…”
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Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG‐6 expression in a tumor type‐specific manner
Published in The FEBS journal (01-09-2019)“…Hyaluronan is a glycosaminoglycan normally present in the extracellular matrix in most tissues. Hyaluronan is a crucial player in many processes associated…”
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Targeting the Tumor Extracellular Matrix by the Natural Molecule 4-Methylumbelliferone: A Complementary and Alternative Cancer Therapeutic Strategy
Published in Frontiers in oncology (04-10-2021)“…In antineoplastic therapy, one of the challenges is to adjust the treatment to the needs of each patient and reduce the toxicity caused by conventional…”
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Postoperative Curving and Upward Displacement of Deep Brain Stimulation Electrodes Caused by Brain Shift
Published in Neurosurgery (01-07-2010)“…Abstract BACKGROUND Accurate electrode position is important for the efficacy of deep brain stimulation (DBS). Several reports revealed errors during…”
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Poly(aspartic acid) Biohydrogel as the Base of a New Hybrid Conducting Material
Published in International journal of molecular sciences (06-12-2021)“…In the present study, a composite made of conducting polymer, poly(3,4-ethylenedioxythiophene) (PEDOT), and a biodegradable hydrogel of poly(aspartic acid)…”
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The effects of sulfated hyaluronan in breast, lung and colorectal carcinoma and monocytes/macrophages cells: Its role in angiogenesis and tumor progression
Published in IUBMB life (01-10-2022)“…Hyaluronan (HA) is a component of the extracellular matrix (ECM) it is the main non‐sulfated glycosaminoglycan able to modulate cell behavior in the healthy…”
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Coexistence of deep brain stimulators and cardiac implantable electronic devices: A systematic review of safety
Published in Parkinsonism & related disorders (01-07-2021)“…As the number of patients implanted with deep brain stimulation systems increases, coexistence with cardiac implantable electronic devices (CIEDs) poses…”
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Mycobacterium bovis Infection of a Deep Brain Stimulation System Following Intravesical Bacillus Calmette-Guérin (BCG) Instillation
Published in Journal of Parkinson's disease (01-01-2024)“…Deep brain stimulation (DBS) is an advanced treatment in Parkinson’s disease. We describe a 71-year-old patient in whom the DBS got infected with Mycobacterium…”
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Genetic insights into Graminella nigrifrons Competence for maize fine streak virus infection and transmission
Published in PloS one (24-11-2014)“…Most plant-infecting rhabdoviruses are transmitted by one or a few closely related insect species. Additionally, intraspecific differences in transmission…”
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Fecal microbiota transplantation for Parkinson's disease using levodopa – carbidopa intestinal gel percutaneous endoscopic gastro-jejeunal tube
Published in Parkinsonism & related disorders (01-06-2023)“…We report a patient with a 5-year diagnosis of akinetic-rigid Parkinson's disease under treatment with Levodopa-Carbidopa Intestinal Gel therapy through a…”
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Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells
Published in Biomolecules (Basel, Switzerland) (09-02-2021)“…UDP-glucose-dehydrogenase (UGDH) synthesizes UDP-glucuronic acid. It is involved in epirubicin detoxification and hyaluronan synthesis. This work aimed to…”
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Phosphoinositide 3-kinase δ inhibition promotes antitumor responses but antagonizes checkpoint inhibitors
Published in JCI insight (07-06-2018)“…Multiple modes of immunosuppression restrain immune function within tumors. We previously reported that phosphoinositide 3-kinase δ (PI3Kδ) inactivation in…”
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Adenoid tissue rhinopharyngeal obstruction grading based on fiberendoscopic findings: a novel approach to therapeutic management
Published in International journal of pediatric otorhinolaryngology (01-12-2003)“…Objective: A grading into four classes of hypertrophied adenoid rhinopharyngeal obstructions in children on the basis of fiberendoscopic findings to outline an…”
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Co-treatment of tumor cells with hyaluronan plus doxorubicin affects endothelial cell behavior independently of VEGF expression
Published in Oncotarget (27-11-2018)“…Hyaluronan, the main glycosaminoglycan of extracellular matrices, is concentrated in tissues with high cell proliferation and migration rates. In cancer,…”
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Postoperative Displacement of Deep Brain Stimulation Electrodes Related to Lead-Anchoring Technique
Published in Neurosurgery (01-10-2013)“…Abstract BACKGROUND: Displacement of deep brain stimulation (DBS) electrodes may occur after surgery, especially due to large subdural air collections, but…”
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