Search Results - "Fiore, Nancy C."

Cell Proliferation Arrest within Intrathymic Lymphocyte Progenitor Cells Causes Thymic Atrophy Mediated by the Aryl Hydrocarbon Receptor by Laiosa, Michael D, Wyman, Amber, Murante, Francis G, Fiore, Nancy C, Staples, J. Erin, Gasiewicz, Thomas A, Silverstone, Allen E

“…Activation of the aryl hydrocarbon receptor (AHR), a basic helix-loop-helix transcription factor, in lymphocytes by the immunosuppressive environmental…”
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Thymic Alterations Induced by 2,3,7,8-Tetrachlorodibenzo- p-Dioxin Are Strictly Dependent on Aryl Hydrocarbon Receptor Activation in Hemopoietic Cells by Staples, J. Erin, Murante, Francis G, Fiore, Nancy C, Gasiewicz, Thomas A, Silverstone, Allen E

“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related congeners affect the immune system, causing immunosuppression and thymic atrophy in a variety of animal…”
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Differential Effects of Diethylstilbestrol and 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Thymocyte Differentiation, Proliferation, and Apoptosis in bcl-2 Transgenic Mouse Fetal Thymus Organ Culture by Lai, Zhi-Wei, Fiore, Nancy C., Hahn, Peter J., Gasiewicz, Thomas A., Silverstone, Allen E.

“…Both the estrogenic drug diethylstilbestrol (DES) and the pervasive environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) inhibit thymocyte…”
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2,3,7,8-Tetrachlorodibenzo-p-dioxin Causes Alterations in Lymphocyte Development and Thymic Atrophy in Hemopoietic Chimeras Generated from Mice Deficient in ARNT2 by Laiosa, Michael D., Lai, Zhi-Wei, Thurmond, T. Scott, Fiore, Nancy C., DeRossi, Charles, Holdener, Bernadette C., Gasiewicz, Thomas A., Silverstone, Allen E.

“…It is well established that dioxins cause a variety of toxic effects and syndromes including alterations of lymphocyte development. Exposure to the…”
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2,3,7,8-Tetrachlorodibenzo-p-dioxin and Diethylstilbestrol Affect Thymocytes at Different Stages of Development in Fetal Thymus Organ Culture by Lai, Zhi-Wei, Fiore, Nancy C., Gasiewicz, Thomas A., Silverstone, Allen E.

“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and estrogen induce thymic atrophy and alter thymocyte development. In the present study we investigate whether TCDD…”
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Bcl2-Independent Chromatin Cleavage is a Very Early Event during Induction of Apoptosis in Mouse Thymocytes after Treatment with Either Dexamethasone or Ionizing Radiation by Hahn, Peter J., Lai, Zhi-Wei, Nevaldine, Barbara, Schiff, Ninel, Fiore, Nancy C., Silverstone, Allen E.

“…Hahn, P. J., Lai, Z-W., Nevaldine, B., Schiff, N., Fiore, N. C. and Silverstone, A. E. Bcl2-Independent Chromatin Cleavage is a Very Early Event during…”
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Estrogen receptor alpha is necessary in thymic development and estradiol-induced thymic alterations by Staples, J E, Gasiewicz, T A, Fiore, N C, Lubahn, D B, Korach, K S, Silverstone, A E

“…Estrogens affect the development, maturation, and function of multiple organ systems, including the immune system. One of the main targets of estrogens in the…”
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Bc12-independent chromatin cleavage is a very early event during induction of apoptosis in mouse thymocytes after treatment with either dexamethasone or ionizing radiation by HAHN, Peter J, LAI, Zhi-Wei, NEVALDINE, Barbara, SCHIFF, Ninel, FIORE, Nancy C, SILVERSTONE, Allen E

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Overexpression of the Anti-apoptotic Oncogene, bcl-2, in the Thymus Does Not Prevent Thymic Atrophy Induced by Estradiol or 2,3,7,8-Tetrachlorodibenzo-p-Dioxin by Staples, J.Erin, Fiore, Nancy C., Frazier, Donald E., Gasiewicz, Thomas A., Silverstone, Allen E.

“…Dexamethasone (Dex), estradiol (E2), and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) all affect the immune system, causing immunosuppression and thymic atrophy…”
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Dexamethasone, beta-estradiol, and 2,3,7,8-tetrachlorodibenzo-p-dioxin elicit thymic atrophy through different cellular targets by Silverstone, A E, Frazier, Jr, D E, Fiore, N C, Soults, J A, Gasiewicz, T A

“…The effects of single doses of dexamethasone (DEX), beta-estradiol-17-valerate (E2), and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the kinetics of thymic…”
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Serum-mediated leukemia cell destruction in AKR mice by Kassel, R L, Old, L J, Carswell, E A, Fiore, N C, Hardy, Jr, W D

“…AKR mice with spontaneous leukemia were infused with normal serum from a variety of species. Leukemia cell destruction was produced by serum from strains of…”
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Estrogen Receptor {alpha} Is Necessary in Thymic Development and Estradiol-Induced Thymic Alterations by Staples, J. Erin, Gasiewicz, Thomas A, Fiore, Nancy C, Lubahn, Dennis B, Korach, Kenneth S, Silverstone, Allen E

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SERUM-MEDIATED LEUKEMIA CELL DESTRUCTION IN AKR MICE: ROLE OF COMPLEMENT IN THE PHENOMENON by Kassel, Robert L., Old, Lloyd J., Carswell, Elizabeth A., Fiore, Nancy C., Hardy, William D.

“…AKR mice with spontaneous leukemia were infused with normal serum from a variety of species. Leukemia cell destruction was produced by serum from strains of…”
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