Search Results - "Finzi, Diana"

Quantitating Protein Synthesis, Degradation, and Endogenous Antigen Processing by Princiotta, Michael F., Finzi, Diana, Qian, Shu-Bing, Gibbs, James, Schuchmann, Sebastian, Buttgereit, Frank, Bennink, Jack R., Yewdell, Jonathan W.

“…Using L929 cells, we quantitated the macroeconomics of protein synthesis and degradation and the microeconomics of producing MHC class I associated peptides…”
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Viral Alteration of Cellular Translational Machinery Increases Defective Ribosomal Products by BERGLUND, Peter, FINZI, Diana, BENNINK, Jack R, YEWDELL, Jonathan W

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Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy by Finzi, Diana, Hermankova, Monika, Pierson, Theodore, Carruth, Lucy M., Buck, Christopher, Chaisson, Richard E., Quinn, Thomas C., Chadwick, Karen, Margolick, Joseph, Brookmeyer, Ronald, Gallant, Joel, Markowitz, Martin, Ho, David D., Richman, Douglas D., Siliciano, Robert F.

“…The hypothesis that quiescent CD4$^+$ T lymphocytes carrying proviral DNA provide a reservoir for human immunodeficiency virus-type 1 (HIV-1) in patients on…”
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Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection by Chun, Tae-Wook, Carruth, Lucy, Finzi, Diana, Shen, Xuefei, DiGiuseppe, Joseph A, Taylor, Harry, Hermankova, Monika, Chadwick, Karen, Margolick, Joseph, Quinn, Thomas C, Kuo, Yen-Hong, Brookmeyer, Ronald, Zeiger, Martha A, Barditch-Crovo, Patricia, Siliciano, Robert F

“…The capacity of HIV-1 to establish latent infection of CD4+ T cells may allow viral persistence despite immune responses and antiretroviral therapy…”
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Characterization of Chemokine Receptor Utilization of Viruses in the Latent Reservoir for Human Immunodeficiency Virus Type 1 by Pierson, T, Hoffman, T L, Blankson, J, Finzi, D, Chadwick, K, Margolick, J B, Buck, C, Siliciano, J D, Doms, R W, Siliciano, R F

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Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4 + T cells by Siliciano, Robert F, Siliciano, Janet D, Kajdas, Joleen, Finzi, Diana, Quinn, Thomas C, Chadwick, Karen, Margolick, Joseph B, Kovacs, Colin, Gange, Stephen J

“…Latent HIV-1 persists in resting memory CD4+ T cells, even in patients receiving highly active antiretroviral therapy (HAART). It has been unclear how stable…”
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Progress Toward Curing HIV Infections With Hematopoietic Stem Cell Transplantation by Smiley, Stephen T., Singh, Anjali, Read, Sarah W., Sharma, Opendra K., Finzi, Diana, Lane, Clifford, Rice, Jeffrey S.

“…Combination antiretroviral therapy can suppress human immunodeficiency virus (HIV) infection but cannot completely eradicate the virus. A major obstacle in the…”
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Latent infection of CD4 + T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy by Siliciano, Robert F, Finzi, Diana, Blankson, Joel, Siliciano, Janet D, Margolick, Joseph B, Chadwick, Karen, Pierson, Theodore, Smith, Kendall, Lisziewicz, Julianna, Lori, Franco, Flexner, Charles, Quinn, Thomas C, Chaisson, Richard E, Rosenberg, Eric, Walker, Bruce, Gange, Stephen, Gallant, Joel

“…Combination therapy for HIV-1 infection can reduce plasma virus to undetectable levels, indicating that prolonged treatment might eradicate the infection…”
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Viral Dynamics in HIV-1 Infection by Finzi, Diana, Siliciano, Robert F

“…A great deal of progress has been made in understanding the molecular biology of HIV-1 replication. Nevertheless, critical aspects of AIDS pathogenesis remain…”
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Defective virus drives human immunodeficiency virus infection, persistence, and pathogenesis by Finzi, Diana, Plaeger, Susan F, Dieffenbach, Carl W

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In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency by Chun, Tae-Wook, Finzi, Diana, Margolick, Joseph, Chadwick, Karen, Schwartz, David, Siliciano, Robert F

“…Although it is presumed that the integration of HIV-1 into the genome of infected CD4+ T lymphocytes allows viral persistence, there has been little direct…”
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A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children by Persaud, D, Pierson, T, Ruff, C, Finzi, D, Chadwick, K R, Margolick, J B, Ruff, A, Hutton, N, Ray, S, Siliciano, R F

“…HIV-1 persists in a latent state in resting CD4(+) T lymphocytes of infected adults despite prolonged highly active antiretroviral therapy (HAART). To…”
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Defining and solving the essential protein–protein interactions in HIV infection by Finzi, Diana, Dieffenbach, Carl W., Basavappa, Ravi

“…The structure determination of macromolecular complexes is entering a new era. The methods of optical microscopy, electron microscopy, X-ray crystallography,…”
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Biphasic Decay of Latently Infected CD4+ T Cells in Acute Human Immunodeficiency Virus Type 1 Infection by Blankson, Joel N., Finzi, Diana, Pierson, Theodore C., Sabundayo, Beulah P., Chadwick, Karen, Margolick, Joseph B., Quinn, Thomas C., Siliciano, Robert F.

“…Latent infection of resting CD4+ T cells represents a major barrier to eradication of human immunodeficiency virus type 1 (HIV-1). The establishment and rate…”
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Treatment of Human Immunodeficiency Virus Infection with Hydroxyurea, Didanosine, and a Protease Inhibitor before Seroconversion Is Associated with Normalized Immune Parameters and Limited Viral Reservoir by Lori, Franco, Jessen, Heiko, Lieberman, Judy, Finzi, Diana, Rosenberg, Eric, Tinelli, Carmine, Walker, Bruce, Siliciano, Robert F., Lisziewicz, Julianna

“…Current treatments for human immunodeficiency virus (HIV) require uninterrupted drug administration because they are unable to reconstitute the immune response…”
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The Possible Role of Hepatitis A Virus in the Pathogenesis of Atherosclerosis by Zhu, Jianhui, Quyyumi, Arshed A., Norman, James E., Costello, Rene, Csako, Gyorgy, Epstein, Stephen E.

“…The possible association between hepatitis A virus (HAV) infection and coronary artery disease (CAD) was studied. Blood from 391 patients undergoing coronary…”
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HIV-1 suppression by early treatment with hydroxyurea, didanosine, and a protease inhibitor by Lisziewicz, Julianna, Jessen, Heiko, Finzi, Diana, Siliciano, Robert F, Lori, Franco

“…A study investigated the antiviral efficacy of combination therapies for HIV-1 suppression by targeting simultaneously reservoir cells and the virus. The…”
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Treatment of human immunodeficiency virus infection with hydroxyurea, didanosine, and a protease inhibitor before serconversion is associated with normalized immune parameters by Franco, Lori, Jessen, Heiko, Lieberman, Judy, Finzi, Diana

“…Current treatments for human immunodeficiency virus (HIV) require uninterrupted drug administration because they are unable to reconstitute the immune response…”
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Taking aim at HIV replication by Finzi, Diana, Siliciano, Robert F

“…Impressive progress has been made in the development of drugs that inhibit human immunodeficiency virus replication. A new study indicates that mycophenolic…”
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Latently infected resting CD4 T cells: A barrier to HIV -1 eradication by Finzi, Diana

“…Treatment of HIV-infected patients with highly active antiretroviral therapy (HAART) results in a dramatic decrease in plasma viral load to undetectable…”
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