Search Results - "Finucane, F."

Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals by Finucane, F. M, Luan, J, Wareham, N. J, Sharp, S. J, O'Rahilly, S, Balkau, B, Flyvbjerg, A, Walker, M, Højlund, K, Nolan, J. J, Savage, D. B

“…Aims/hypothesis Obesity is the dominant cause of insulin resistance. In adult humans it is characterised by a combination of adipocyte hypertrophy and, to a…”
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SGLT2 inhibitor-induced euglycaemic diabetic ketoacidosis may be due to abrupt, severe and transient impaired glucose sensing in susceptible individuals with a hitherto unrecognised beta cell SGLT variant by Finucane, F.M.

“…Euglycaemic diabetic ketoacidosis (EDKA) is a rare complication of treatment with SGLT2 inhibitors in patients with type 2 diabetes. Uncertainty remains about…”
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effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial by Finucane, F. M, Sharp, S. J, Purslow, L. R, Horton, K, Horton, J, Savage, D. B, Brage, S, Besson, H, De Lucia Rolfe, E, Sleigh, A, Martin, H. J, Aihie Sayer, A, Cooper, C, Ekelund, U, Griffin, S. J, Wareham, N. J

“…Aims/hypothesis We sought to determine the effect of an aerobic exercise intervention on clustered metabolic risk and related outcomes in healthy older adults…”
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The leptin to adiponectin ratio (LAR) is reduced by sleeve gastrectomy in adults with severe obesity: a prospective cohort study by Rafey, M. F., Fang, C. E. H., Ioana, I., Griffin, H., Hynes, M., O’Brien, T., McAnena, O., O’Shea, P., Collins, C., Davenport, C., Finucane, F. M.

“…Bariatric surgery is known to reduce leptin and increase adiponectin levels, but the influence of sleeve gastrectomy on the leptin: adiponectin ratio (LAR), a…”
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Incidence and pathophysiology of severe hyponatraemia in neurosurgical patients by Sherlock, M, O’Sullivan, E, Agha, A, Behan, L A, Owens, D, Finucane, F, Rawluk, D, Tormey, W, Thompson, C J

“…Background:Hyponatraemia is a well-recognised complication of neurosurgical conditions, but the incidence and implications have not been well…”
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Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in beta cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training by Burns, N, Finucane, F. M, Hatunic, M, Gilman, M, Murphy, M, Gasparro, D, Mari, A, Gastaldelli, A, Nolan, J. J

“…Aims/hypothesis Early-onset type 2 diabetes is associated with marked visceral obesity and extreme insulin resistance, but its pathogenesis and response to…”
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Radiological remission and recovery of thirst appreciation after infliximab therapy in adipsic diabetes insipidus secondary to neurosarcoidosis by O'Reilly, M W, Sexton, D J, Dennedy, M C, Counihan, T J, Finucane, F M, O'Brien, T, O'Regan, A W

“…Neurosarcoidosis is a rare and aggressive variant of systemic sarcoidosis which may result in hypothalamic-pituitary dysfunction. We report a case of…”
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Abnormal regulation of thirst and vasopressin secretion following surgery for craniopharyngioma by Smith, D., Finucane, F., Phillips, J., Baylis, P. H., Finucane, J., Tormey, W., Thompson, C. J.

“…Summary objective  In this study we aimed to establish the frequency of postoperative diabetes insipidus and the incidence and characteristics of abnormalities…”
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Plasma visfatin is reduced after aerobic exercise in early onset type 2 diabetes mellitus by Brema, I., Hatunic, M., Finucane, F., Burns, N., Nolan, J. J., Haider, D., Wolzt, M., Ludvik, B.

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Glycaemic control is harder to achieve than blood pressure or lipid control in Irish adults with type 1 diabetes by Cotter, T.G, Dinneen, S.F, Healy, D.A, Bell, M.J, Cunningham, A, O'Shea, P.M, Dunne, F, O’Brien, T, Finucane, F.M

“…Highlights • We sought to determine the extent to which targets for glycaemic control and vascular risk factor reduction are met in an Irish university…”
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Should we screen for childhood obesity? by Geoghegan, R., Kelly, C., Finucane, F. M.

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Obesity in Irish youth: epidemiology and implications by Finucane, F. M.

“…The worldwide epidemic of type 2 diabetes has been paralleled by a marked increase in the prevalence of obesity, particularly in younger people. This will…”
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Genomic variants at the PINK1 locus are associated with transcript abundance and plasma nonesterified fatty acid concentrations in European whites by Franks, P.W, Scheele, C, Loos, R.J.F, Nielsen, A.R, Finucane, F.M, Wahlestedt, C, Pedersen, B.K, Wareham, N.J, Timmons, J.A

“…The purpose of this study was to characterize associations between PINK1 genotypes, PINK1 transcript levels, and metabolic phenotypes in healthy adults and…”
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Reduced insulin requirements during participation in the DAFNE (dose adjustment for normal eating) structured education programme by Leelarathna, L, Ward, C, Davenport, K, Donald, S, Housden, A, Finucane, F.M, Evans, M

“…Abstract Dose adjustment for normal eating (DAFNE) is a well-established structured education programme for patients with type 1 diabetes. We conducted a…”
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Altered respiratory function is associated with increased metabolic risk, independently of adiposity, fitness and physical activity by Steele, R. M., Finucane, F. M., Simmons, R. K., Griffin, S. J., Wareham, N. J., Ekelund, U.

“…Aims  Reduced lung function is associated with an adverse metabolic risk profile, even after adjusting for body fatness. However, previous observations may…”
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The corporate political activity of the food industry in Ireland: an analysis and proposed solutions by Campbell, N, Finucane, F, Walsh, M, Reilly, K

“…Abstract Background The study consisted of mapping the corporate political activity (CPA) of the food industry in Ireland. Following that study, we plan to…”
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An intensive nurse-led, multi-interventional clinic is more successful in achieving vascular risk reduction targets than standard diabetes care by MacMahon Tone, J., Agha, A., Sherlock, M., Finucane, F., Tormey, W., Thompson, C. J.

“…Background The aim of this research was to determine whether an intensive, nurse-led clinic could achieve recommended vascular risk reduction targets in…”
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Mortality among diabetics in a national sample by Kleinman, J C, Donahue, R P, Harris, M I, Finucane, F F, Madans, J H, Brock, D B

“…The authors compare the mortality experience of a national sample of diabetic men and women with their nondiabetic counterparts. The study population consists…”
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Propylthiouracil induced C-ANCA positive agranulocytosis complicating Graves’ thyrotoxicosis in pregnancy by Finucane, F. M., O’Connell, J., Kinsley, B. T.

“…Background Thionamide induced agranulocytosis is associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCA) in some patients. This poses a…”
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Elevated blood pressure in overweight and obese Irish children by Finucane, F. M., Pittock, S., Fallon, M., Hatunic, M., Ong, K., Burns, N., Costigan, C., Murphy, N., Nolan, J. J.

“…Background The Irish childhood obesity epidemic, one of the highest ranking internationally, represents a major threat to public health. We sought to perform a…”
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