Search Results - "Finnström, Niklas"
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EXPRESSION OF CYP3A ISOFORMS AND P-GLYCOPROTEIN IN HUMAN STOMACH, JEJUNUM AND ILEUM
Published in Clinical and experimental pharmacology & physiology (01-11-2007)“…SUMMARY 1 CYP3A isoforms metabolise a diverse array of clinically important drugs and P‐glycoprotein (P‐gp), a transmembrane efflux pump, can extrude a wide…”
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Cytochromes P450 and MDR1 mRNA expression along the human gastrointestinal tract
Published in British journal of clinical pharmacology (01-07-2005)“…Aim The aim of this study was to quantify the mRNA expression of three cytochromes P450 (CYP) and P‐glycoprotein (P‐gp) in the human gastrointestinal (GI)…”
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Expression of cytochromes P450 3A and P-glycoprotein in human large intestine in paired tumour and normal samples
Published in Basic & clinical pharmacology & toxicology (01-04-2007)“…Our objective was to investigate the expression of different cytochromes P450 3A (CYP3A4, CYP3A5, and CYP3A7) and P-glycoprotein (ABCB1) genes along the human…”
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Aspergillus PCR: One Step Closer to Standardization
Published in Journal of Clinical Microbiology (01-04-2010)“…PCR has been used as an aid in the diagnosis of invasive aspergillosis for almost 2 decades. A lack of standardization has limited both its acceptance as a…”
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Evaluation of Aspergillus PCR Protocols for Testing Serum Specimens
Published in Journal of Clinical Microbiology (01-11-2011)“…OA Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Critical Stages of Extracting DNA from Aspergillus fumigatus in Whole-Blood Specimens
Published in Journal of Clinical Microbiology (01-10-2010)“…A standardized protocol for extracting DNA from Aspergillus fumigatus has been proposed by the European Aspergillus PCR Initiative (EAPCRI). Using…”
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Expression of cytochrome P450 and MDR1 in patients with proctitis
Published in Upsala journal of medical sciences (2007)“…Background. The aim of this study was to investigate the effect of inflammation on the gene expression of three cytochrome P450's (CYP) and P-glycoprotein…”
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Expression of Cytochromes P450 3A and P‐Glycoprotein in Human Large Intestinse in Paired Tumour and Normal Samples
Published in Basic & clinical pharmacology & toxicology (01-04-2007)“…: Our objective was to investigate the expression of different cytochromes P450 3A (CYP3A4, CYP3A5, and CYP3A7) and P‐glycoprotein (ABCB1) genes along the…”
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Analysis of varicella-zoster virus and herpes simplex virus in various clinical samples by the use of different PCR assays
Published in Journal of virological methods (01-09-2009)“…Rapid and reliable detection of varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) and -2 (HSV-2) is of clinical significance in…”
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Gene Expression of a Novel Cytochrome P450 of the CYP4F Subfamily in Human Seminal Vesicles
Published in Biochemical and biophysical research communications (22-07-1999)“…19R-Hydroxyprostaglandins are major components of human seminal fluid. They are apparently formed in the seminal vesicles by NADPH-dependent ω2-hydroxylation…”
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Independent patterns of cytochrome P450 gene expression in liver and blood in patients with suspected liver disease
Published in European journal of clinical pharmacology (01-08-2001)“…Assessment of liver metabolism using blood samples was tested by comparison of cytochrome P450 (CYP) gene expression in paired liver and blood samples from 13…”
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Independent patterns of cytochrome P 450 gene expression in liver and blood in patients with suspected liver disease
Published in European journal of clinical pharmacology (01-08-2001)Get full text
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Effect of cyclophosphamide on gene expression of cytochromes P450 and β-actin in the HL-60 cell line
Published in European journal of pharmacology (09-08-2002)“…Many studies have demonstrated that cyclophosphamide (CPA) can affect hepatic cytochrome P450 (CYP) isoenzyme activity in animals. We have investigated the…”
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Hepatitis B virus DNA quantitation and detection of core promoter, precore and polymerase mutations in chronic hepatitis B: evaluation and clinical usefulness of three new commercial assays
Published in Le infezioni in medicina (01-06-2005)“…HBV-DNA quantitation, the HBe antigen status and the appearance of mutations in the core promoter, precore and polymerase regions are important elements in the…”
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Insulin-like growth factor 1 (IGF-I) effects on sex-specific cytochrome P450 enzymes in normal and hypophysectomised male rats
Published in Biochemical pharmacology (15-08-1998)“…The role of growth hormone (GH) in the regulation of the sex-differentiated rat cytochrome P450 (CYP) enzymes has been extensively studied. However, little is…”
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Independent patterns of cytochrome P sub(450) gene expression in liver and blood in patients with suspected liver disease
Published in European journal of clinical pharmacology (01-08-2001)“…Objective: Assessment of liver metabolism using blood samples was tested by comparison of cytochrome P sub(450) (CYP) gene expression in paired liver and blood…”
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Gene Expression of Cytochrome P450 1B1 and 2D6 in Leukocytes in Human Pregnancy
Published in Pharmacology & toxicology (01-06-2003)“…: We investigated the influence of human pregnancy on gene expression of two cytochrome P450 enzymes in white blood cells. Cytochrome P450 1B1 (CYP1B1)…”
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Amino Acid Differences at Positions 10, 11, and 104 Explain the Profound Catalytic Differences between Two Murine Pi-Class Glutathione S-Transferases
Published in Biochemistry (Easton) (18-07-1995)“…The glutathione S-transferases play a pivotal role in the detoxification of toxic and carcinogenic electrophiles. We have previously reported the isolation of…”
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Quantitation of cytochrome P450 mRNAs in patients with suspected liver diseases as assessed by reverse transcriptase-polymerase chain reaction
Published in The Journal of laboratory and clinical medicine (01-08-1999)“…The cytochrome P450 system (CYP) is vital for the oxidation and detoxification of numerous drugs and other xenobiotics in the liver. Many of the CYP enzymes…”
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