Search Results - "Finno, C. J."

Functional phenotyping of the CYP2D6 probe drug codeine in the horse by Gretler, S R, Finno, C J, Kass, P H, Knych, H K

“…In humans, the drug metabolizing enzyme CYP2D6 is highly polymorphic resulting in substantial differences in the metabolism of drugs including…”
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Identification of long non-coding RNA in the horse transcriptome by Scott, E Y, Mansour, T, Bellone, R R, Brown, C T, Mienaltowski, M J, Penedo, M C, Ross, P J, Valberg, S J, Murray, J D, Finno, C J

“…Efforts to resolve the transcribed sequences in the equine genome have focused on protein-coding RNA. The transcription of the intergenic regions, although…”
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Applied equine genetics by Finno, C. J, Bannasch, D. L

“…Genome sequencing of the domestic horse and subsequent advancements in the field of equine genomics have led to an explosion in the development of tools for…”
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Tissue resolved, gene structure refined equine transcriptome by Mansour, T A, Scott, E Y, Finno, C J, Bellone, R R, Mienaltowski, M J, Penedo, M C, Ross, P J, Valberg, S J, Murray, J D, Brown, C T

“…Transcriptome interpretation relies on a good-quality reference transcriptome for accurate quantification of gene expression as well as functional analysis of…”
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Deletion of 2.7 kb near HOXD3 in an Arabian horse with occipitoatlantoaxial malformation by Bordbari, M. H., Penedo, M. C. T., Aleman, M., Valberg, S. J., Mickelson, J., Finno, C. J.

“…Summary In the horse, the term occipitoatlantoaxial malformation (OAAM) is used to describe a developmental defect in which the first cervical vertebra (atlas)…”
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The tocopherol transfer protein mediates vitamin E trafficking between cerebellar astrocytes and neurons by Ulatowski, L., Ghelfi, Mikel, West, Ryan, Atkinson, J., Finno, C.J., Manor, D.

“…Alpha-tocopherol (vitamin E) is an essential nutrient that functions as a major lipid-soluble antioxidant in humans. The alpha-tocopherol transfer protein…”
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Endogenous Transplacental Transmission of Neospora hughesi in Naturally Infected Horses by Pusterla, N, Conrad, P. A, Packham, A. E, Mapes, S. M, Finno, C. J, Gardner, I. A, Barr, B. C, Ferraro, G. L, Wilson, W. D

“…Over a 2-yr study period, we investigated possible endogenous transplacental transmission of Neospora hughesi in 74 mare and foal pairs following the diagnosis…”
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Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post‐genome era by Raudsepp, T., Finno, C. J., Bellone, R. R., Petersen, J. L.

“…Summary The horse reference genome from the Thoroughbred mare Twilight has been available for a decade and, together with advances in genomics technologies,…”
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A Comparative Review of Vitamin E and Associated Equine Disorders by Finno, C.J., Valberg, S.J.

“…Vitamin E is a primary chain‐breaking antioxidant that prevents cyclic propagation of lipid peroxidation. Across species, vitamin E is essential for normal…”
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Hoof wall separation disease: A review by Finno, C. J.

“…Summary Hoof wall separation disease (HWSD) is a genetic defect in Connemara ponies characterized by separation and cracking of the dorsal hoof wall. The…”
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Clinical and histopathological features of myofibrillar myopathy in Warmblood horses by Valberg, S. J., Nicholson, A. M., Lewis, S. S., Reardon, R. A., Finno, C. J.

“…Summary Background To report a novel exertional myopathy, myofibrillar myopathy (MFM) in Warmblood (WB) horses. Objectives To 1) describe the distinctive…”
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Suspected myofibrillar myopathy in Arabian horses with a history of exertional rhabdomyolysis by Valberg, S. J., McKenzie, E. C., Eyrich, L. V., Shivers, J., Barnes, N. E., Finno, C. J.

“…Summary Reasons for performing study Although exertional rhabdomyolysis (ER) is common in Arabian horses, there are no dedicated studies describing…”
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Warmblood fragile foal syndrome type 1 mutation (PLOD1 c.2032G>A) is not associated with catastrophic breakdown and has a low allele frequency in the Thoroughbred breed by Bellone, R. R., Ocampo, N. R., Hughes, S. S., Le, V., Arthur, R., Finno, C. J., Penedo, M. C. T.

“…Summary Background Catastrophic fractures are among the most common cause of fatalities in racehorses. Several factors, including genetics, likely contribute…”
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Investigation of Known Genetic Mutations of Arabian Horses in Egyptian Arabian Foals with Juvenile Idiopathic Epilepsy by Aleman, M., Finno, C.J., Weich, K., Penedo, M.C.T.

“…Background The carrier status of lavender foal syndrome (LFS), cerebellar abiotrophy (CA), severe combined immunodeficiency (SCID), and occipitoatlantoaxial…”
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Effects of feeding two RRR‐α‐tocopherol formulations on serum, cerebrospinal fluid and muscle α‐tocopherol concentrations in horses with subclinical vitamin E deficiency by Brown, J. C., Valberg, S. J., Hogg, M., Finno, C. J.

“…Summary Background Alpha‐tocopherol (α‐TP) supplementation is recommended for the prevention of various equine neuromuscular disorders. Formulations available…”
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Variation in MUTYH expression in Arabian horses with Cerebellar Abiotrophy by Scott, E.Y., Woolard, K.D., Finno, C.J., Penedo, M.C.T., Murray, J.D.

“…•Equine CA is associated with a SNP compromising MUTYH expression.•Horses with CA demonstrate altered methylation patterns in the MUTYH promoter.•Horses with…”
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Blood and Cerebrospinal Fluid α‐Tocopherol and Selenium Concentrations in Neonatal Foals with Neuroaxonal Dystrophy by Finno, C.J., Estell, K.E., Katzman, S., Winfield, L., Rendahl, A., Textor, J., Bannasch, D.L., Puschner, B.

“…BACKGROUND: Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (NAD/EDM) is a neurodegenerative disorder affecting genetically predisposed…”
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Generation of an equine biobank to be used for Functional Annotation of Animal Genomes project by Burns, E. N., Bordbari, M. H., Mienaltowski, M. J., Affolter, V. K., Barro, M. V., Gianino, F., Gianino, G., Giulotto, E., Kalbfleisch, T. S., Katzman, S. A., Lassaline, M., Leeb, T., Mack, M., Müller, E. J., MacLeod, J. N., Ming‐Whitfield, B., Alanis, C. R., Raudsepp, T., Scott, E., Vig, S., Zhou, H., Petersen, J. L., Bellone, R. R., Finno, C. J.

“…Summary The Functional Annotation of Animal Genomes (FAANG) project aims to identify genomic regulatory elements in both sexes across multiple stages of…”
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Evidence of the Primary Afferent Tracts Undergoing Neurodegeneration in Horses With Equine Degenerative Myeloencephalopathy Based on Calretinin Immunohistochemical Localization by Finno, C. J., Valberg, S. J., Shivers, J., D’Almeida, E., Armién, A. G.

“…Equine degenerative myeloencephalopathy (EDM) is characterized by a symmetric general proprioceptive ataxia in young horses, and is likely underdiagnosed for 2…”
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Concurrent Equine Degenerative Myeloencephalopathy and Equine Motor Neuron Disease in Three Young Horses by Finno, C.J., Miller, A.D., Sisó, S., Divers, T., Gianino, G., Barro, M.V., Valberg, S.J.

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