Search Results - "Finniff, Bridget A."

Protocol for modeling acquired resistance to targeted therapeutics in adherent and suspension cancer cell lines via in situ resistance assay by Sealover, Nancy E., Hughes, Jacob M., Theard, Patricia L., Chatterjee, Deepan, Linke, Amanda J., Finniff, Bridget A., Daley, Brianna R., Lewis, Robert E., Kortum, Robert L.

“…Acquired resistance to oncogene-targeted therapies is the major driver of mortality for patients with cancer. Here, we present a 6-to-16-week assay to model…”
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SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma by Daley, Brianna R, Sealover, Nancy E, Finniff, Bridget A, Hughes, Jacob M, Sheffels, Erin, Gerlach, Daniel, Hofmann, Marco H, Kostyrko, Kaja, LaMorte, Joseph P, Linke, Amanda, Beckley, Zaria, Frank, Andrew M, Lewis, Robert E, Wilkerson, Matthew D, Dalgard, Clifton, Kortum, Robert L

“…The clinical effectiveness of KRASG12C inhibitors (G12Ci) is limited both by intrinsic and acquired resistance, necessitating the development of combination…”
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