Search Results - "Finneman, Jari I"

Systematic Investigation of EDC/sNHS-Mediated Bioconjugation Reactions for Carboxylated Peptide Substrates by Totaro, Kyle A, Liao, Xiaoli, Bhattacharya, Keshab, Finneman, Jari I, Sperry, Justin B, Massa, Mark A, Thorn, Jennifer, Ho, Sa V, Pentelute, Bradley L

“…1-Ethyl-3-(3-(dimethylamino)­propyl)­carbodiimide (EDC) bioconjugations have been utilized in preparing variants for medical research. While there have been…”
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Anti-nicotine vaccines: Comparison of adjuvanted CRM197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates by McCluskie, Michael J., Thorn, Jennifer, Gervais, David P., Stead, David R., Zhang, Ningli, Benoit, Michelle, Cartier, Janna, Kim, In-Jeong, Bhattacharya, Keshab, Finneman, Jari I., Merson, James R., Davis, Heather L.

“…Anti-nicotine vaccines comprise nicotine-like haptens conjugated to a carrier protein plus adjuvant(s). Unfortunately, those tested clinically have failed to…”
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Molecular attributes of conjugate antigen influence function of antibodies induced by anti-nicotine vaccine in mice and non-human primates by McCluskie, Michael J., Thorn, Jennifer, Mehelic, Paul R., Kolhe, Parag, Bhattacharya, Keshab, Finneman, Jari I., Stead, David R., Piatchek, Michele Bailey, Zhang, Ningli, Chikh, Ghania, Cartier, Janna, Evans, Dana M., Merson, James R., Davis, Heather L.

“…Anti-nicotine vaccines aim to prevent nicotine entering the brain, and thus reduce or eliminate the reward that drives nicotine addiction. Those tested in…”
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Process development of a FGF21 protein–antibody conjugate by Dirksen, Anouk, Davis, Keith A., Collins, Joe T., Bhattacharya, Keshab, Finneman, Jari I., Pepin, Erin L., Ryczek, Jeffrey S., Brown, Paul W., Wellborn, William B., Mangalathillam, Ratish, Evans, Brad P., Pozzo, Mark J., Finn, Rory F.

“…A scalable, viable process was developed for the Fibroblast Growth Factor 21 (FGF21) protein‐antibody conjugate, CVX‐343, an extended half‐life therapeutic for…”
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Novel approach for optimization of a 'difficult' peptide synthesis by utilizing quantitative reaction monitoring assays by Finneman, Jari I., Pozzo, Mark J.

“…Three different synthetic strategies were tested to synthesize EGFRvIII peptide (1), which is a functional variant of the epidermal growth factor receptor, a…”
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Studies of the Mechanisms of Adduction of 2‘-Deoxyadenosine with Styrene Oxide and Polycyclic Aromatic Hydrocarbon Dihydrodiol Epoxides by Kim, Hye-Young H, Finneman, Jari I, Harris, Constance M, Harris, Thomas M

“…The mechanism of adduction of 2‘-deoxyadenosine by styrene oxide and polycyclic aromatic hydrocarbon dihydrodiol epoxides has been explored using 15N6-labeled…”
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Mechanisms of Benzyl Group Transfer in the Decay of (E)-Arylmethanediazoates and Aryldiazomethanes in Aqueous Solutions by Finneman, Jari I, Fishbein, James C

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Mechanisms of Decomposition of (Z)-2,2,2-Trifluoro-1-arylethanediazoates in Aqueous Media by Finneman, Jari I, Fishbein, James C

“…A study of the kinetics of decay of three (Z)-2,2,2-trifluoro-1-arylethanediazoates at 25 °C in aqueous media, 4% 2-propanol by volume, ionic strength 1 M…”
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Changes in Transition State Structure for Protonation of Aryldiazomethanes in Aqueous Solutions by Finneman, Jari I, Fishbein, James C

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Anti-nicotine vaccines: Comparison of adjuvanted CRM 197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates by McCluskie, Michael J., Thorn, Jennifer, Gervais, David P., Stead, David R., Zhang, Ningli, Benoit, Michelle, Cartier, Janna, Kim, In-Jeong, Bhattacharya, Keshab, Finneman, Jari I., Merson, James R., Davis, Heather L.

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(E)-2-Butanediazoic acid decomposes via a diazonium ion intermediate by Finneman, Jari I, Ho, Jian, Fishbein, James C

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P rocess development of a FGF21 protein–antibody conjugate by Dirksen, Anouk, Davis, Keith A., Collins, Joe T., Bhattacharya, Keshab, Finneman, Jari I., Pepin, Erin L., Ryczek, Jeffrey S., Brown, Paul W., Wellborn, William B., Mangalathillam, Ratish, Evans, Brad P., Pozzo, Mark J., Finn, Rory F.

“…A scalable, viable process was developed for the Fibroblast Growth Factor 21 (FGF21) protein‐antibody conjugate, CVX‐343, an extended half‐life therapeutic for…”
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Mechanism of decomposition of (E)-methanediazoate in aqueous solutions by Hovinen, Jari, Finneman, Jari I., Satapathy, Surya N., Ho, Jian, Fishbein, James C.

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