Search Results - "Finn, P D"

Alterations in the endocannabinoid system in the rat valproic acid model of autism by Kerr, D.M., Downey, L., Conboy, M., Finn, D.P., Roche, M.

“…•Prenatal VPA exposure elicits autistic-like behaviour during adolescence.•Social exposure increases hippocampal anandamide levels in VPA exposed rats.•DAGLα…”
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Time-course of nigrostriatal neurodegeneration and neuroinflammation in the 6-hydroxydopamine-induced axonal and terminal lesion models of Parkinson's disease in the rat by Walsh, S, Finn, D.P, Dowd, E

“…Abstract The pathogenesis of Parkinson's disease is thought to involve a self-sustaining cycle of neuroinflammation and neurodegeneration. In order to develop…”
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Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala by Burke, N. N., Geoghegan, E., Kerr, D. M., Moriarty, O., Finn, D. P., Roche, M.

“…The association between chronic pain and depression is widely recognized, the comorbidity of which leads to a heavier disease burden, increased disability and…”
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Enhanced nociceptive responding in two rat models of depression is associated with alterations in monoamine levels in discrete brain regions by Burke, N.N, Hayes, E, Calpin, P, Kerr, D.M, Moriarty, O, Finn, D.P, Roche, M

“…Abstract Altered pain responding in depression is a widely recognized but poorly understood phenomenon. The present study investigated nociceptive responding…”
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The monoacylglycerol lipase inhibitor JZL184 attenuates LPS‐induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action by Kerr, DM, Harhen, B, Okine, BN, Egan, LJ, Finn, DP, Roche, M

“…Background and purpose JZL184 is a selective inhibitor of monoacylglycerol lipase (MAGL), the enzyme that preferentially catabolizes the endocannabinoid…”
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A quasi-steady state mathematical model of an integrated ground source heat pump for building space control by Corberan, J.M., Finn, D.P., Montagud, C.M., Murphy, F.T., Edwards, K.C.

“…This paper is concerned with the development of a mathematical model, capable of describing the quasi-steady state performance of an integrated ground source…”
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The endocannabinoid system in the rat dorsolateral periaqueductal grey mediates fear‐conditioned analgesia and controls fear expression in the presence of nociceptive tone by Olango, WM, Roche, M, Ford, GK, Harhen, B, Finn, DP

“…BACKGROUND AND PURPOSE Endocannabinoids in the midbrain periaqueductal grey (PAG) modulate nociception and unconditioned stress‐induced analgesia; however,…”
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Pharmacological activity of ibuprofen released from mesoporous silica by Lang, Y., Finn, D. P., Pandit, A., Walsh, P. J.

“…Novel drug delivery systems (DDS) to improve the pharmacokinetic profile of hydrophobic drugs following oral administration are an area of keen interest in…”
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Heat transfer correlations for low approach evaporative cooling systems in buildings by Costelloe, B., Finn, D.P.

“…The experimental performance of an open industrial scale cooling tower, utilising small approach temperature differences (1–3 K), for rejection of heat at the…”
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Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats by Finn, D.P., Jhaveri, M.D., Beckett, S.R.G., Roe, C.H., Kendall, D.A., Marsden, C.A., Chapman, V.

“…The analgesic potential of cannabinoids may be hampered by their ability to produce aversive emotion when administered systemically. We investigated the…”
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Co-simulation of a HVAC system-integrated phase change material thermal storage unit by Jones, A.T., Finn, D.P.

“…A co-simulation environment, consisting of a detailed mathematical model of a thermal energy storage unit which is incorporated with an EnergyPlus simulation…”
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Behavioral, central monoaminergic and hypothalamo–pituitary–adrenal axis correlates of fear-conditioned analgesia in rats by Finn, D.P., Jhaveri, M.D., Beckett, S.R.G., Madjd, A., Kendall, D.A., Marsden, C.A., Chapman, V.

“…Fear-conditioned analgesia is an important survival response which is expressed upon re-exposure to a context previously paired with a noxious stimulus. The…”
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Thermal energy storage using phase change material: Analysis of partial tank charging and discharging on system performance in a building cooling application by McKenna, P., Turner, W.J.N., Finn, D.P.

“…•Partial charging of a phase change material thermal energy storage tank is investigated.•The phase change material is water and the application is building…”
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Evidence for differential modulation of conditioned aversion and fear-conditioned analgesia by CB1 receptors by Finn, D. P., Beckett, S. R. G., Richardson, D., Kendall, D. A., Marsden, C. A., Chapman, V.

“…Fear‐conditioned analgesia is an important survival response mediated by substrates controlling nociception and aversion. Cannabinoid1 (CB1) receptors play an…”
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CB1 and CB2 cannabinoid receptor antagonists prevent minocycline-induced neuroprotection following traumatic brain injury in mice by Lopez-Rodriguez, Ana Belen, Siopi, Eleni, Finn, David P, Marchand-Leroux, Catherine, Garcia-Segura, Luis M, Jafarian-Tehrani, Mehrnaz, Viveros, Maria-Paz

“…Traumatic brain injury (TBI) and its consequences represent one of the leading causes of death in young adults. This lesion mediates glial activation and the…”
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Effects of coadministration of cannabinoids and morphine on nociceptive behaviour, brain monoamines and HPA axis activity in a rat model of persistent pain by Finn, D. P., Beckett, S. R. G., Roe, C. H., Madjd, A., Fone, K. C. F., Kendall, D. A., Marsden, C. A., Chapman, V.

“…The antinociceptive effects of Δ9‐tetrahydrocannabinol (Δ9‐THC) have been widely described; however, its therapeutic potential may be limited by secondary…”
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Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate by Rea, K, Roche, M, Finn, D P

“…Recent physiological, pharmacological and anatomical studies provide evidence that one of the main roles of the endocannabinoid system in the brain is the…”
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Geocooling with integrated PCM thermal energy storage in a commercial building by McKenna, P., Turner, W.J.N., Finn, D.P.

“…Geocooling and thermal energy storage (TES) are two strategies that could help alleviate the energy and carbon emission burden from cooling commercial…”
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Endomorphins and activation of the hypothalamo-pituitary-adrenal axis by Coventry, TL, Jessop, DS, Finn, DP, Crabb, MD, Kinoshita, H, Harbuz, MS

“…Endomorphin (EM)-1 and EM-2 are opioid tetrapeptides recently located in the central nervous system and immune tissues with high selectivity and affinity for…”
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Comparison of responses of ventral posterolateral and posterior complex thalamic neurons in naïve rats and rats with hindpaw inflammation: μ-opioid receptor mediated inhibitions by Abdul Aziz, A.A., Finn, D.P., Mason, R., Chapman, V.

“…The aim of the present study was to compare the effects of morphine on thalamic neuronal responses in naïve rats and rats with carrageenan-induced hindpaw…”
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