Search Results - "Finn, M. G."

Introduction: Click Chemistry by Devaraj, Neal K, Finn, M. G

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Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry by Dong, Jiajia, Krasnova, Larissa, Finn, M. G., Sharpless, K. Barry

“…Aryl sulfonyl chlorides (e.g. Ts‐Cl) are beloved of organic chemists as the most commonly used SVI electrophiles, and the parent sulfuryl chloride, O2SVICl2,…”
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Analysis and Optimization of Copper-Catalyzed Azide-Alkyne Cycloaddition for Bioconjugation by Hong, Vu, Presolski, Stanislav I, Ma, Celia, Finn, M.G

“…How to click with biomolecules: Copper‐catalyzed azide–alkyne cycloaddition has been optimized for use with biological molecules. The key development is the…”
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In situ click chemistry: probing the binding landscapes of biological molecules by Mamidyala, Sreeman K, Finn, M G

“…Combinatorial approaches to the discovery of new functional molecules are well established among chemists and biologists, inspired in large measure by the…”
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Thiabicyclononane-Based Antimicrobial Polycations by Geng, Zhishuai, Finn, M. G

“…Bicyclo­[3.3.1]­nonane (BCN) polycations were synthesized by the reaction of the bivalent electrophile thiabicyclo[3.3.1]­nonane dinitrate with a series of…”
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N -Aryl–linked spirocyclic polymers for membrane separations of complex hydrocarbon mixtures by Thompson, Kirstie A., Mathias, Ronita, Kim, Daeok, Kim, Jihoon, Rangnekar, Neel, Johnson, J. R., Hoy, Scott J., Bechis, Irene, Tarzia, Andrew, Jelfs, Kim E., McCool, Benjamin A., Livingston, Andrew G., Lively, Ryan P., Finn, M. G.

“…Separating organics without distillation Hydrocarbon distillation is a widespread and energy-intensive process. Membranes might offer an alternative approach,…”
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Protective Epitope Discovery and Design of MUC1-based Vaccine for Effective Tumor Protections in Immunotolerant Mice by Wu, Xuanjun, Yin, Zhaojun, McKay, Craig, Pett, Christian, Yu, Jin, Schorlemer, Manuel, Gohl, Trevor, Sungsuwan, Suttipun, Ramadan, Sherif, Baniel, Claire, Allmon, Anthony, Das, Rupali, Westerlind, Ulrika, Finn, M. G, Huang, Xuefei

“…Human mucin-1 (MUC1) is a highly attractive antigen for the development of anticancer vaccines. However, in human clinical trials of multiple MUC1 based…”
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Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents by Blanchard, Emmeline L., Vanover, Daryll, Bawage, Swapnil Subhash, Tiwari, Pooja Munnilal, Rotolo, Laura, Beyersdorf, Jared, Peck, Hannah E., Bruno, Nicholas C., Hincapie, Robert, Michel, Frank, Murray, Jackelyn, Sadhwani, Heena, Vanderheyden, Bob, Finn, M. G., Brinton, Margo A., Lafontaine, Eric R., Hogan, Robert J., Zurla, Chiara, Santangelo, Philip J.

“…Cas13a has been used to target RNA viruses in cell culture, but efficacy has not been demonstrated in animal models. In this study, we used messenger RNA…”
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Engineering the PP7 Virus Capsid as a Peptide Display Platform by Zhao, Liangjun, Kopylov, Mykhailo, Potter, Clinton S, Carragher, Bridget, Finn, M. G

“…As self-assembling polyvalent nanoscale structures that can tolerate substantial genetic and chemical modification, virus-like particles are useful in a…”
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Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung by Rotolo, Laura, Vanover, Daryll, Bruno, Nicholas C., Peck, Hannah E., Zurla, Chiara, Murray, Jackelyn, Noel, Richard K., O’Farrell, Laura, Araínga, Mariluz, Orr-Burks, Nichole, Joo, Jae Yeon, Chaves, Lorena C. S., Jung, Younghun, Beyersdorf, Jared, Gumber, Sanjeev, Guerrero-Ferreira, Ricardo, Cornejo, Santiago, Thoresen, Merrilee, Olivier, Alicia K., Kuo, Katie M., Gumbart, James C., Woolums, Amelia R., Villinger, Francois, Lafontaine, Eric R., Hogan, Robert J., Finn, M. G., Santangelo, Philip J.

“…Messenger RNA has now been used to vaccinate millions of people. However, the diversity of pulmonary pathologies, including infections, genetic disorders,…”
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Solution-processable polytriazoles from spirocyclic monomers for membrane-based hydrocarbon separations by Bruno, Nicholas C., Mathias, Ronita, Lee, Young Joo, Zhu, Guanghui, Ahn, Yun-Ho, Rangnekar, Neel D., Johnson, J. R., Hoy, Scott, Bechis, Irene, Tarzia, Andrew, Jelfs, Kim E., McCool, Benjamin A., Lively, Ryan, Finn, M. G.

“…The thermal distillation of crude oil mixtures is an energy-intensive process, accounting for nearly 1% of global energy consumption. Membrane-based…”
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Thiol-Selective Fluorogenic Probes for Labeling and Release by Hong, Vu, Kislukhin, Alexander A, Finn, M. G

“…Thiol alkylation is a powerful technique for the labeling of proteins. We report a new class of highly reactive, selective, and fluorogenic probes for thiols…”
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Glycan-Modified Virus-like Particles Evoke T Helper Type 1‑like Immune Responses by Alam, Mohammad Murshid, Jarvis, Cassie M, Hincapie, Robert, McKay, Craig S, Schimer, Jiri, Sanhueza, Carlos A, Xu, Ke, Diehl, Roger C, Finn, M. G, Kiessling, Laura L

“…Dendritic cells (DCs) are highly effective antigen-presenting cells that shape immune responses. Vaccines that deliver antigen to the DCs can harness their…”
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Bioconjugation by Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition by Wang, Qian, Chan, Timothy R, Hilgraf, Robert, Fokin, Valery V, Sharpless, K. Barry, Finn, M. G

“…The copper-catalyzed cycloaddition reaction between azides and alkynes functions efficiently in aqueous solution in the presence of a tris(triazolyl)amine…”
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Ligand-Accelerated Cu-Catalyzed Azide−Alkyne Cycloaddition:  A Mechanistic Report by Rodionov, Valentin O, Presolski, Stanislav I, Díaz Díaz, David, Fokin, Valery V, Finn, M. G

“…The experimental rate law for the Cu(I)-catalyzed azide−alkyne cycloaddition (CuAAC) reaction was found to vary in complex ways with concentration, the…”
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Core-Clickable PEG-Branch-Azide Bivalent-Bottle-Brush Polymers by ROMP: Grafting-Through and Clicking-To by Johnson, Jeremiah A, Lu, Ying Y, Burts, Alan O, Lim, Yeon-Hee, Finn, M. G, Koberstein, Jeffrey T, Turro, Nicholas J, Tirrell, David A, Grubbs, Robert H

“…The combination of highly efficient polymerizations with modular “click” coupling reactions has enabled the synthesis of a wide variety of novel nanoscopic…”
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Synthesis and Immunological Evaluation of Disaccharide Bearing MUC‑1 Glycopeptide Conjugates with Virus-like Particles by Wu, Xuanjun, McKay, Craig, Pett, Christian, Yu, Jin, Schorlemer, Manuel, Ramadan, Sherif, Lang, Shuyao, Behren, Sandra, Westerlind, Ulrika, Finn, M. G, Huang, Xuefei

“…Mucin-1 (MUC1) is a highly attractive antigenic target for anticancer vaccines. Naturally existing MUC1 can contain multiple types of O-linked glycans,…”
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Azide-Substituted Polylactide: A Biodegradable Substrate for Antimicrobial Materials via Click Chemistry Attachment of Quaternary Ammonium Groups by Kalelkar, Pranav P, Geng, Zhishuai, Finn, M. G, Collard, David M

“…Polylactide (PL) co-polymers substituted with pendant azide groups (azido-PL) were synthesized by the nucleophilic conjugate addition of 3-azido-1-propanethiol…”
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Taming Chlorine Azide: Access to 1,2-Azidochlorides from Alkenes by Valiulin, Roman A, Mamidyala, Sreeman, Finn, M. G

“…The in situ preparation and trapping of chlorine azide provided a versatile one-pot method for the azidochlorination of alkenes. Gaseous ClN3 generated from…”
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Data-driven predictions of complex organic mixture permeation in polymer membranes by Lee, Young Joo, Chen, Lihua, Nistane, Janhavi, Jang, Hye Youn, Weber, Dylan J., Scott, Joseph K., Rangnekar, Neel D., Marshall, Bennett D., Li, Wenjun, Johnson, J. R., Bruno, Nicholas C., Finn, M. G., Ramprasad, Rampi, Lively, Ryan P.

“…Membrane-based organic solvent separations are rapidly emerging as a promising class of technologies for enhancing the energy efficiency of existing separation…”
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