Search Results - "Finlayson, Neil"

Full spectrum fluorescence lifetime imaging with 0.5 nm spectral and 50 ps temporal resolution by Williams, Gareth O. S., Williams, Elvira, Finlayson, Neil, Erdogan, Ahmet T., Wang, Qiang, Fernandes, Susan, Akram, Ahsan R., Dhaliwal, Kev, Henderson, Robert K., Girkin, John M., Bradley, Mark

“…The use of optical techniques to interrogate wide ranging samples from semiconductors to biological tissue for rapid analysis and diagnostics has gained wide…”
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Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: A randomized double blinded phase I/IIa trial by Chandra, Janin, Woo, Wai-Ping, Dutton, Julie L, Xu, Yan, Li, Bo, Kinrade, Sally, Druce, Julian, Finlayson, Neil, Griffin, Paul, Laing, Kerry J, Koelle, David M, Frazer, Ian H

“…Genital herpes simplex infection affects more than 500 million people worldwide. We have previously shown that COR-1, a therapeutic HSV-2 polynucleotide…”
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DNA Vaccine Encoding HPV16 Oncogenes E6 and E7 Induces Potent Cell-mediated and Humoral Immunity Which Protects in Tumor Challenge and Drives E7-expressing Skin Graft Rejection by Chandra, Janin, Dutton, Julie L, Li, Bo, Woo, Wai-Ping, Xu, Yan, Tolley, Lynn K, Yong, Michelle, Wells, James W, R Leggatt, Graham, Finlayson, Neil, Frazer, Ian H

“…We have previously shown that a novel DNA vaccine technology of codon optimization and the addition of ubiquitin sequences enhanced immunogenicity of a herpes…”
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A phase Ib study to assess the safety of the human papillomavirus DNA vaccine (AMV002) in combination with durvalumab for HPV-associated oropharyngeal squamous cell carcinoma by Ladwa, Rahul, Chandra, Janin, Woo, Wai-Ping, Finlayson, Neil, Liu, Howard, McGrath, Margaret, See, Adrienne, Hughes, Brett G, Cooper, Caroline L, Jackson, Jim E, Dzienis, Marcin, Xu, Yan, Panizza, Benedict, Frazer, Ian, Porceddu, Sandro V

“…Programmed cell death ligand 1 (PD-L1) inhibitors have limited efficacy as monotherapy in patients with recurrent/metastatic (R/M) Human Papilloma Virus (HPV)…”
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Red-Shifted Environmental Fluorophores and Their Use for the Detection of Gram-Negative Bacteria by Megia-Fernandez, Alicia, Klausen, Maxime, Mills, Bethany, Brown, Gillian E., McEwan, Heather, Finlayson, Neil, Dhaliwal, Kevin, Bradley, Mark

“…Two novel, water-soluble, merocyanine fluorophores were readily prepared by microwave-assisted synthesis. Full optical characterization was performed in a…”
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Spectral analysis of nonlinear systems by Black, Sandy, Christie, David, Finlayson, Neil

“…Two separate nonlinear differential systems are investigated in the frequency and time domains using plots generated by Mathematica. Spectral density plots are…”
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A CMOS SPAD Line Sensor With Per-Pixel Histogramming TDC for Time-Resolved Multispectral Imaging by Erdogan, Ahmet T., Walker, Richard, Finlayson, Neil, Krstajic, Nikola, Williams, Gareth, Girkin, John, Henderson, Robert

“…A 512 <inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula> 16 single photon avalanche diode (SPAD)-based line sensor is designed in…”
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Fast and Robust Single-Exponential Decay Recovery From Noisy Fluorescence Lifetime Imaging by Taimori, Ali, Humphries, Duncan, Williams, Gareth, Dhaliwal, Kevin, Finlayson, Neil, Hopgood, James

“…Fluorescence lifetime imaging is a valuable technique for probing characteristics of wide ranging samples and sensing of the molecular environment. However,…”
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A Novel Fit-Flexible Fluorescence Soft Imager: Tri-Sensing of Intensity, Fall-Time, and Life Profile by Taimori, Ali, Mills, Bethany, Gaughan, Erin, Ali, Aysha, Dhaliwal, Kevin, Williams, Gareth, Finlayson, Neil, Hopgood, James R.

“…Time-resolved fluorescence imaging techniques, like confocal fluorescence lifetime imaging microscopy, are powerful photonic instrumentation tools of modern…”
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A High Dynamic Range 128 × 120 3-D Stacked CMOS SPAD Image Sensor SoC for Fluorescence Microendoscopy by Erdogan, Ahmet T., Al Abbas, Tarek, Finlayson, Neil, Hopkinson, Charlotte, Gyongy, Istvan, Almer, Oscar, Dutton, Neale A. W., Henderson, Robert K.

“…A miniaturized 1.4 mm <inline-formula> <tex-math notation="LaTeX">\times \,\, 1.4 </tex-math></inline-formula> mm, <inline-formula> <tex-math…”
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Development of a high-speed line-scanning fluorescence lifetime imaging microscope for biological imaging by Mai, Hanning, Jarman, Anneliese, Erdogan, Ahmet T, Treacy, Conor, Finlayson, Neil, Henderson, Robert K, Poland, Simon P

“…We report the development of a novel line-scanning microscope capable of acquiring high-speed time-correlated single-photon counting (TCSPC)-based fluorescence…”
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Solitary pulmonary nodule imaging approaches and the role of optical fibre-based technologies by Fernandes, Susan, Williams, Gareth, Williams, Elvira, Ehrlich, Katjana, Stone, James, Finlayson, Neil, Bradley, Mark, Thomson, Robert R, Akram, Ahsan R, Dhaliwal, Kevin

“…Solitary pulmonary nodules (SPNs) are a clinical challenge, given there is no single clinical sign or radiological feature that definitively identifies a…”
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A CMOS SPAD Sensor With a Multi-Event Folded Flash Time-to-Digital Converter for Ultra-Fast Optical Transient Capture by Al Abbas, Tarek, Dutton, Neale A. W., Almer, Oscar, Finlayson, Neil, Della Rocca, Francescopaolo Mattioli, Henderson, Robert

“…A digital silicon photomultiplier in 130-nm CMOS imaging technology implements time-correlated single photon counting at an order of magnitude beyond the…”
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Combined fluorescence lifetime and surface topographical imaging of biological tissue by Hopkinson, Charlotte, Matheson, Andrew B, Finlayson, Neil, Tanner, Michael G, Akram, Ahsan R, Henderson, Robert K

“…In this work a combined fluorescence lifetime and surface topographical imaging system is demonstrated. Based around a 126 × 192 time resolved single photon…”
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ATLAS: a large array, on-chip compute SPAD camera for multispeckle diffuse correlation spectroscopy by Gorman, Alistair, Finlayson, Neil, Erdogan, Ahmet T., Fisher, Lars, Wang, Yining, Mattioli Della Rocca, Francescopaolo, Mai, Hanning, Sie, Edbert J., Marsili, Francesco, Henderson, Robert K.

“…We present ATLAS, a 512 × 512 single-photon avalanche diode (SPAD) array with embedded autocorrelation computation, implemented in 3D-stacked CMOS technology,…”
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Applications of machine learning in time-domain fluorescence lifetime imaging: a review by Gouzou, Dorian, Taimori, Ali, Haloubi, Tarek, Finlayson, Neil, Wang, Qiang, Hopgood, James R, Vallejo, Marta

“…Many medical imaging modalities have benefited from recent advances in Machine Learning (ML), specifically in deep learning, such as neural networks. Computers…”
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A layer-level multi-scale architecture for lung cancer classification with fluorescence lifetime imaging endomicroscopy by Wang, Qiang, Hopgood, James R., Fernandes, Susan, Finlayson, Neil, Williams, Gareth O. S., Akram, Ahsan R., Dhaliwal, Kevin, Vallejo, Marta

“…In this paper, we introduce our unique dataset of fluorescence lifetime imaging endo/microscopy (FLIM), containing over 100,000 different FLIM images collected…”
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Deep learning-assisted co-registration of full-spectral autofluorescence lifetime microscopic images with H E-stained histology images by Qiang Wang, Susan Fernandes, Gareth O. S. Williams, Neil Finlayson, Ahsan R. Akram, Kevin Dhaliwal, James R. Hopgood, Marta Vallejo

“…Using unsupervised image-to-image synthesis, homography regression-based co-registration of fluorescence-histology images is improved and can be used on…”
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A 512×512 SPAD Laser Speckle Autocorrelation Imager in Stacked 65/40nm CMOS by Della Rocca, Francescopaolo Mattioli, Sie, Edbert J., Erdogan, Ahmet T., Fisher, Lars, Matheson, Andrew B., Finlayson, Neil, Gorman, Alistair, Gyongy, Istvan, Mai, Hanning, Lachaud, Thierry, Forsyth, Russell, Marsili, Francesco, Henderson, Robert K.

“…We present a single-photon avalanche diode (SPAD) autocorrelation imager implemented in 65/40nm 3D-stacked CMOS for laser speckle blood flow monitoring. The…”
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An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1 by Dutton, Julie L., Woo, Wai-Ping, Chandra, Janin, Xu, Yan, Li, Bo, Finlayson, Neil, Griffin, Paul, Frazer, Ian H.

“…This paper describes a single site, open-label Phase I clinical trial evaluating the safety, tolerability and immunogenicity in healthy volunteers of a herpes…”
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