Search Results - "Finlay‐Jones, J. J."

Modulation of the immune system by UV radiation: more than just the effects of vitamin D? by Hart, Prue H, Gorman, Shelley, Finlay-Jones, John J

“…Key Points Ultraviolet (UV) irradiation of skin and consequent suppression of local and systemic immune responses have been associated with reduced severity of…”
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Tea tree oil reduces histamine-induced skin inflammation by Koh, K.J., Pearce, A.L., Marshman, G., Finlay-Jones, J.J., Hart, P.H.

“…Summary Background  Tea tree oil is the essential oil steam‐distilled from Melaleuca alternifolia , an Australian native plant. In recent years it has become…”
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Suppression of the asthmatic phenotype by ultraviolet B-induced, antigen-specific regulatory cells by McGlade, J. P., Gorman, S., Zosky, G. R., Larcombe, A. N., Sly, P. D., Finlay-Jones, J. J., Turner, D. J., Hart, P. H.

“…Summary Background Over recent decades, there has been a significant global increase in the prevalence of asthma, an inflammatory disease of the respiratory…”
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Dermal mast cells determine susceptibility to ultraviolet B-induced systemic suppression of contact hypersensitivity responses in mice by Hart, P H, Grimbaldeston, M A, Swift, G J, Jaksic, A, Noonan, F P, Finlay-Jones, J J

“…Different strains of mice have varying susceptibilities to ultraviolet radiation (UV) of wavelength 280-320 nm (UVB) for 50% suppression of systemic contact…”
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Differential responses of human monocytes and macrophages to IL-4 and IL-13 by Hart, Prue H., Bonder, Claudine S., Balogh, Julianna, Dickensheets, Harold L., Donnelly, Raymond P., Finlay‐Jones, John J.

“…The primary interleukin‐4 (IL‐4) receptor complex on monocytes (type I IL‐4 receptor) includes the 140‐kDa α chain (IL‐4Rα) and the IL‐2 receptor γ chain, γc,…”
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S100A8 Induction in Keratinocytes by Ultraviolet A Irradiation Is Dependent on Reactive Oxygen Intermediates by Grimbaldeston, Michele A., Geczy, Carolyn L., Tedla, Nicodemus, Finlay-Jones, John J., Hart, Prue H.

“…Cutaneous exposure to ultraviolet (UV) A (320–400 nm) results in the formation of damaging reactive oxygen intermediates, which are implicated as mediators of…”
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Terpinen-4-ol, the main component of the essential oil of Melaleuca alternifolia (tea tree oil), suppresses inflammatory mediator production by activated human monocytes by Hart, P H, Brand, C, Carson, C F, Riley, T V, Prager, R H, Finlay-Jones, J J

“…To evaluate potential antiinflammatory properties of tea tree oil, the essential oil steam distilled from the Australian native plant, Melaleuca alternifolia…”
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The controversial role of vitamin D in the skin: immunosuppression vs. photoprotection by Kuritzky, L. A., Finlay-Jones, J. J., Hart, P. H.

“…Summary Vitamin D is produced in the skin by ultraviolet (UV) B radiation (290–320 nm). The active metabolite 1,25‐dihydroxyvitamin D3 [1,25(OH)2D3] is made…”
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Association between melanoma and dermal mast cell prevalence in sun-unexposed skin by Grimbaldeston, M.A., Pearce, A.L., Robertson, B.O., Coventry, B.J., Marshman, G., Finlay-Jones, J.J., Hart, P.H.

“…Summary Background  Both exposure to intermittent intense sunlight during childhood and ultraviolet (UV) radiation‐induced immunomodulation have been directly…”
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The effect of ultraviolet radiation exposure on the prevalence of mast cells in human skin by Grimbaldeston, M.A., Simpson, A., Finlay-Jones, J.J., Hart, P.H.

“…Summary Background Dermal mast cells have been implicated as important effector cells in innate immunity, hypersensitivity responses and ultraviolet…”
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Sunlight, Immunosuppression And Skin Cancer: Role Of Histamine And Mast Cells by Hart, Prue H, Grimbaldeston, Michele A, Finlay-Jones, John J

“…SUMMARY 1. The development into tumours of skin cells transformed by ultraviolet (UV) B radiation of wavelengths 290–320 nm is enhanced by the ability of UVB…”
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cis-Urocanic Acid Stimulates Neuropeptide Release from Peripheral Sensory Nerves by Khalil, Zeinab, Townley, Scott L., Grimbaldeston, Michele A., Finlay-Jones, John J., Hart, Prue H.

“…Previous studies using an antibody to cis-urocanic acid and mast-cell-depleted mice implicated both cis-urocanic acid and mast cells in the mechanisms by which…”
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Type-1 and type-2 cytokines in human late-gestation decidual tissue by Jones, C A, Finlay-Jones, J J, Hart, P H

“…Evidence suggests that successful pregnancy in rodents requires the preferential stimulation of type-2 cytokine production by gestation-associated tissues. The…”
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Inflammatory processes in a murine model of intra-abdominal abscess formation by Finlay‐Jones, John J., Davies, Kate V. L., Sturm, Lana P., Kenny, Peter A., Hart, Prue H.

“…Abscess formation has been viewed as a host defense strategy to contain the spread of infection. However, abscesses are also serious and life‐threatening…”
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Effect of Both Ultraviolet B Irradiation and Histamine Receptor Function on Allergic Responses to an Inhaled Antigen by McGlade, Jacqueline P, Gorman, Shelley, Lenzo, Jason C, Tan, Jamie W, Watanabe, Takeshi, Finlay-Jones, John J, Thomas, Wayne R, Hart, Prue H

“…Exposure of skin to UVB radiation (290-320 nm) modulates the immune system, with most studies showing a suppression of Th1-driven immune responses. This study…”
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The water-soluble components of the essential oil of Melaleuca alternifolia (tea tree oil) suppress the production of superoxide by human monocytes, but not neutrophils, activated in vitro by Brand, C, Ferrante, A, Prager, R H, Riley, T V, Carson, C F, Finlay-Jones, J J, Hart, P H

“…To evaluate the regulatory properties of the essential oil of Melaleuca alternifolia (tea tree oil) on the production of oxygen derived reactive species by…”
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Nerve Growth Factor, Neuropeptides, and Mast Cells in Ultraviolet-B-Induced Systemic Suppression of Contact Hypersensitivity Responses in Mice by Townley, Scott L., Grimbaldeston, Michele A., Finlay-Jones, John J., Hart, Prue H., Ferguson, Ian, Rush, Robert A., Zhang, Shu-Hua, Zhou, Xin-Fu, Conner, James M.

“…The induction of systemic immunosuppression following ultraviolet B radiation exposure has been linked with the release of inflammatory and immunomodulatory…”
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High Dermal Mast Cell Prevalence is a Predisposing Factor for Basal Cell Carcinoma in Humans by Grimbaldeston, Michele A., Skov, Lone, Baadsgaard, Ole, Skov, Birgit G., Marshman, Gillian, Finlay-Jones, John J., Hart, Prue H.

“…Ultraviolet B radiation (280–320 nm) can initiate skin cancer as well as suppress the immune system, thereby preventing the rejection of ultraviolet-B-induced…”
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Monocytes cultured in cytokine-defined environments differ from freshly isolated monocytes in their responses to IL-4 and IL-10 by Hart, P H, Jones, C A, Finlay-Jones, J J

“…To investigate the regulatory effects of the prototypic Th2 lymphocyte products and potential immunotherapeutic agents interleukin-4 (IL-4) and IL-10 on…”
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A Critical Role for Dermal Mast Cells in Cis-Urocanic Acid-induced Systemic Suppression of Contact Hypersensitivity Responses in Mice by Hart, Prue H., Grimbaldeston, Michele A., Swift, Georgina J., Hosszu, Emma K., Finlay-Jones, John J.

“…Many studies have implicated cu‐urocanic acid (cu‐UCA) in UVB‐induced immunomodulation. The strongest evidence came from studies in mice whereby a cis‐UCA…”
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