Search Results - "Finlay, Brett B"

Early-life interactions between the microbiota and immune system: impact on immune system development and atopic disease by Donald, Katherine, Finlay, B. Brett

“…Prenatal and early postnatal life represent key periods of immune system development. In addition to genetics and host biology, environment has a large and…”
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Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents by Walter, Jens, Armet, Anissa M., Finlay, B. Brett, Shanahan, Fergus

“…Human diseases are increasingly linked with an altered or “dysbiotic” gut microbiota, but whether such changes are causal, consequential, or bystanders to…”
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The Role of Lung and Gut Microbiota in the Pathology of Asthma by Barcik, Weronika, Boutin, Rozlyn C.T., Sokolowska, Milena, Finlay, B. Brett

“…Asthma is a common chronic respiratory disease affecting more than 300 million people worldwide. Clinical features of asthma and its immunological and…”
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The Human Microbiome and Child Growth – First 1000 Days and Beyond by Robertson, Ruairi C., Manges, Amee R., Finlay, B. Brett, Prendergast, Andrew J.

“…The assembly of microbial communities within the gastrointestinal tract during early life plays a critical role in immune, endocrine, metabolic, and other host…”
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Gut microbiota in health and disease by Sekirov, Inna, Russell, Shannon L, Antunes, L Caetano M, Finlay, B Brett

“…Gut microbiota is an assortment of microorganisms inhabiting the length and width of the mammalian gastrointestinal tract. The composition of this microbial…”
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Human Microbiota-Associated Mice: A Model with Challenges by Arrieta, Marie-Claire, Walter, Jens, Finlay, B. Brett

“…Human microbiota-associated (HMA) mice have been used extensively in gut microbiome research. Here we discuss ecological and evolutionary aspects of the…”
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The gut microbiome in human neurological disease: A review by Tremlett, Helen, Bauer, Kylynda C., Appel‐Cresswell, Silke, Finlay, Brett B., Waubant, Emmanuelle

“…Almost half the cells and 1% of the unique genes found in our bodies are human, the rest are from microbes, predominantly bacteria, archaea, fungi, and…”
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Molecular mechanisms of Escherichia coli pathogenicity by Finlay, B. Brett, Croxen, Matthew A

“…Key Points Major advances have been made in our understanding of the molecular mechanisms that are used by pathogenic Escherichia coli to cause disease. In…”
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Can we harness the microbiota to enhance the efficacy of cancer immunotherapy? by Finlay, B. Brett, Goldszmid, Romina, Honda, Kenya, Trinchieri, Giorgio, Wargo, Jennifer, Zitvogel, Laurence

“…There is currently much interest in defining how the microbiota shapes immune responses in the context of cancer. Various studies in both mice and humans have…”
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Association between the intestinal microbiota and allergic sensitization, eczema, and asthma: A systematic review by Zimmermann, Petra, Messina, Nicole, Mohn, William W., Finlay, B. Brett, Curtis, Nigel

“…The intestinal microbiota plays an important role in development of the immune system and regulation of immune responses. This review summarizes the…”
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Early infancy microbial and metabolic alterations affect risk of childhood asthma by Arrieta, Marie-Claire, Stiemsma, Leah T, Dimitriu, Pedro A, Thorson, Lisa, Russell, Shannon, Yurist-Doutsch, Sophie, Kuzeljevic, Boris, Gold, Matthew J, Britton, Heidi M, Lefebvre, Diana L, Subbarao, Padmaja, Mandhane, Piush, Becker, Allan, McNagny, Kelly M, Sears, Malcolm R, Kollmann, Tobias, Mohn, William W, Turvey, Stuart E, Finlay, B Brett

“…Asthma is the most prevalent pediatric chronic disease and affects more than 300 million people worldwide. Recent evidence in mice has identified a "critical…”
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The role of the immune system in governing host-microbe interactions in the intestine by Brown, Eric M, Sadarangani, Manish, Finlay, B Brett

“…The mammalian intestinal tract harbors a diverse community of trillions of microorganisms, which have co-evolved with the host immune system for millions of…”
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Shifting the balance: antibiotic effects on host–microbiota mutualism by Finlay, B. Brett, Willing, Benjamin P, Russell, Shannon L

“…Key Points Antibiotics have substantial direct and indirect effects on the intestinal microbiota; although some of the changes disappear soon after cessation…”
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When a pandemic and an epidemic collide: COVID-19, gut microbiota, and the double burden of malnutrition by Littlejohn, Paula, Finlay, B Brett

“…It is estimated that the COVID-19 pandemic will drastically increase all forms of malnutrition. Of particular concern, yet understated, is the potential to…”
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NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion by Wlodarska, Marta, Thaiss, Christoph A., Nowarski, Roni, Henao-Mejia, Jorge, Zhang, Jian-Ping, Brown, Eric M., Frankel, Gad, Levy, Maayan, Katz, Meirav N., Philbrick, William M., Elinav, Eran, Finlay, B. Brett, Flavell, Richard A.

“…Mucus production by goblet cells of the large intestine serves as a crucial antimicrobial protective mechanism at the interface between the eukaryotic and…”
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Recent Advances in Understanding Enteric Pathogenic Escherichia coli by CROXEN, Matthew A, LAW, Robyn J, SCHOLZ, Roland, KEENEY, Kristie M, WLODARSKA, Marta, FINLAY, B. Brett

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Nonalcoholic Fatty Liver Disease and the Gut-Liver Axis: Exploring an Undernutrition Perspective by Bauer, Kylynda C., Littlejohn, Paula T., Ayala, Victoria, Creus-Cuadros, Anna, Finlay, B. Brett

“…Nonalcoholic fatty liver disease (NAFLD) is a chronic condition affecting one quarter of the global population. Although primarily linked to obesity and…”
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Defining a Healthy Human Gut Microbiome: Current Concepts, Future Directions, and Clinical Applications by Bäckhed, Fredrik, Fraser, Claire M., Ringel, Yehuda, Sanders, Mary Ellen, Sartor, R. Balfour, Sherman, Philip M., Versalovic, James, Young, Vincent, Finlay, B. Brett

“…Indigenous microbiota are an essential component in the modern concept of human health, but the composition and functional characteristics of a healthy…”
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Tight junctions as targets of infectious agents by Guttman, Julian A., Finlay, B. Brett

“…The epithelial barrier is a critical border that segregates luminal material from entering tissues. Essential components of this epithelial fence are physical…”
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Type III Secretion Systems and Disease by Coburn, Bryan, Sekirov, Inna, Finlay, B Brett

“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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