Search Results - "Finkle, Justin D."
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ZYG-9ch-TOG promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis
Published in PLoS genetics (01-11-2022)“…During mitosis, centrosomes serve as microtubule organizing centers that guide the formation of a bipolar spindle. However, oocytes of many species lack…”
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Journal Article -
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Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA
Published in NPJ precision oncology (02-07-2021)“…Liquid biopsy is a valuable precision oncology tool that is increasingly used as a non-invasive approach to identify biomarkers, detect resistance mutations,…”
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Journal Article -
3
Systems Approach to Integrative Biology: An Overview of Statistical Methods to Elucidate Association and Architecture
Published in Integrative and comparative biology (01-07-2014)“…An organismâs ability to maintain a desired physiological response relies extensively on how cellular and molecular signaling networks interpret and react to…”
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Journal Article -
4
Windowed Granger causal inference strategy improves discovery of gene regulatory networks
Published in Proceedings of the National Academy of Sciences - PNAS (27-02-2018)“…Accurate inference of regulatory networks from experimental data facilitates the rapid characterization and understanding of biological systems…”
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Hybrid analysis of gene dynamics predicts context-specific expression and offers regulatory insights
Published in Bioinformatics (01-11-2019)“…Abstract Motivation To understand the regulatory pathways underlying diseases, studies often investigate the differential gene expression between genetically…”
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Longitudinal Shifts of Solid Tumor and Liquid Biopsy Sequencing Concordance in Metastatic Breast Cancer
Published in JCO precision oncology (01-06-2022)“…Tissue-based next-generation sequencing (NGS) in metastatic breast cancer (mBC) is limited by the inability to noninvasively track tumor evolution. Cell-free…”
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Journal Article -
7
ZYG-9.sup.ch-TOG promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis
Published in PLoS genetics (30-11-2022)“…During mitosis, centrosomes serve as microtubule organizing centers that guide the formation of a bipolar spindle. However, oocytes of many species lack…”
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Journal Article -
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Discovering Regulatory Insights from Gene Expression Dynamics
Published 01-01-2019“…Cells are complex, autonomous machines that integrate many environmental cues to execute a desired response. Though this property makes cells versatile, it…”
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Dissertation