Search Results - "Finkin, Shlomo"

Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies by Greaney, Allison J., Starr, Tyler N., Barnes, Christopher O., Weisblum, Yiska, Schmidt, Fabian, Caskey, Marina, Gaebler, Christian, Cho, Alice, Agudelo, Marianna, Finkin, Shlomo, Wang, Zijun, Poston, Daniel, Muecksch, Frauke, Hatziioannou, Theodora, Bieniasz, Paul D., Robbiani, Davide F., Nussenzweig, Michel C., Bjorkman, Pamela J., Bloom, Jesse D.

“…Monoclonal antibodies targeting a variety of epitopes have been isolated from individuals previously infected with SARS-CoV-2, but the relative contributions…”
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Evolution of antibody immunity to SARS-CoV-2 by Gaebler, Christian, Wang, Zijun, Lorenzi, Julio C. C., Muecksch, Frauke, Finkin, Shlomo, Tokuyama, Minami, Cho, Alice, Jankovic, Mila, Schaefer-Babajew, Dennis, Oliveira, Thiago Y., Cipolla, Melissa, Viant, Charlotte, Barnes, Christopher O., Bram, Yaron, Breton, Gaëlle, Hägglöf, Thomas, Mendoza, Pilar, Hurley, Arlene, Turroja, Martina, Gordon, Kristie, Millard, Katrina G., Ramos, Victor, Schmidt, Fabian, Weisblum, Yiska, Jha, Divya, Tankelevich, Michael, Martinez-Delgado, Gustavo, Yee, Jim, Patel, Roshni, Dizon, Juan, Unson-O’Brien, Cecille, Shimeliovich, Irina, Robbiani, Davide F., Zhao, Zhen, Gazumyan, Anna, Schwartz, Robert E., Hatziioannou, Theodora, Bjorkman, Pamela J., Mehandru, Saurabh, Bieniasz, Paul D., Caskey, Marina, Nussenzweig, Michel C.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected 78 million individuals and is responsible for over 1.7 million deaths to date…”
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Protein Amounts of the MYC Transcription Factor Determine Germinal Center B Cell Division Capacity by Finkin, Shlomo, Hartweger, Harald, Oliveira, Thiago Y., Kara, Ervin E., Nussenzweig, Michel C.

“…High-affinity B cell selection in the germinal center (GC) is governed by signals delivered by follicular helper T (Tfh) cells to B cells. Selected B cells…”
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Enhanced SARS-CoV-2 neutralization by dimeric IgA by Wang, Zijun, Lorenzi, Julio C C, Muecksch, Frauke, Finkin, Shlomo, Viant, Charlotte, Gaebler, Christian, Cipolla, Melissa, Hoffmann, Hans-Heinrich, Oliveira, Thiago Y, Oren, Deena A, Ramos, Victor, Nogueira, Lilian, Michailidis, Eleftherios, Robbiani, Davide F, Gazumyan, Anna, Rice, Charles M, Hatziioannou, Theodora, Bieniasz, Paul D, Caskey, Marina, Nussenzweig, Michel C

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), primarily infects cells at mucosal…”
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Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination by Cho, Alice, Muecksch, Frauke, Schaefer-Babajew, Dennis, Wang, Zijun, Finkin, Shlomo, Gaebler, Christian, Ramos, Victor, Cipolla, Melissa, Mendoza, Pilar, Agudelo, Marianna, Bednarski, Eva, DaSilva, Justin, Shimeliovich, Irina, Dizon, Juan, Daga, Mridushi, Millard, Katrina G., Turroja, Martina, Schmidt, Fabian, Zhang, Fengwen, Tanfous, Tarek Ben, Jankovic, Mila, Oliveria, Thiago Y., Gazumyan, Anna, Caskey, Marina, Bieniasz, Paul D., Hatziioannou, Theodora, Nussenzweig, Michel C.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection produces B cell responses that continue to evolve for at least a year. During that time,…”
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mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants by Wang, Zijun, Schmidt, Fabian, Weisblum, Yiska, Muecksch, Frauke, Barnes, Christopher O., Finkin, Shlomo, Schaefer-Babajew, Dennis, Cipolla, Melissa, Gaebler, Christian, Lieberman, Jenna A., Oliveira, Thiago Y., Yang, Zhi, Abernathy, Morgan E., Huey-Tubman, Kathryn E., Hurley, Arlene, Turroja, Martina, West, Kamille A., Gordon, Kristie, Millard, Katrina G., Ramos, Victor, Da Silva, Justin, Xu, Jianliang, Colbert, Robert A., Patel, Roshni, Dizon, Juan, Unson-O’Brien, Cecille, Shimeliovich, Irina, Gazumyan, Anna, Caskey, Marina, Bjorkman, Pamela J., Casellas, Rafael, Hatziioannou, Theodora, Bieniasz, Paul D., Nussenzweig, Michel C.

“…Here we report on the antibody and memory B cell responses of a cohort of 20 volunteers who received the Moderna (mRNA-1273) or Pfizer–BioNTech (BNT162b2)…”
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Convergent antibody responses to SARS-CoV-2 in convalescent individuals by Robbiani, Davide F., Gaebler, Christian, Muecksch, Frauke, Lorenzi, Julio C. C., Wang, Zijun, Cho, Alice, Agudelo, Marianna, Barnes, Christopher O., Gazumyan, Anna, Finkin, Shlomo, Hägglöf, Thomas, Oliveira, Thiago Y., Viant, Charlotte, Hurley, Arlene, Hoffmann, Hans-Heinrich, Millard, Katrina G., Kost, Rhonda G., Cipolla, Melissa, Gordon, Kristie, Bianchini, Filippo, Chen, Spencer T., Ramos, Victor, Patel, Roshni, Dizon, Juan, Shimeliovich, Irina, Mendoza, Pilar, Hartweger, Harald, Nogueira, Lilian, Pack, Maggi, Horowitz, Jill, Schmidt, Fabian, Weisblum, Yiska, Michailidis, Eleftherios, Ashbrook, Alison W., Waltari, Eric, Pak, John E., Huey-Tubman, Kathryn E., Koranda, Nicholas, Hoffman, Pauline R., West, Anthony P., Rice, Charles M., Hatziioannou, Theodora, Bjorkman, Pamela J., Bieniasz, Paul D., Caskey, Marina, Nussenzweig, Michel C.

“…During the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of…”
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Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection by Wang, Zijun, Muecksch, Frauke, Schaefer-Babajew, Dennis, Finkin, Shlomo, Viant, Charlotte, Gaebler, Christian, Hoffmann, Hans- Heinrich, Barnes, Christopher O., Cipolla, Melissa, Ramos, Victor, Oliveira, Thiago Y., Cho, Alice, Schmidt, Fabian, Da Silva, Justin, Bednarski, Eva, Aguado, Lauren, Yee, Jim, Daga, Mridushi, Turroja, Martina, Millard, Katrina G., Jankovic, Mila, Gazumyan, Anna, Zhao, Zhen, Rice, Charles M., Bieniasz, Paul D., Caskey, Marina, Hatziioannou, Theodora, Nussenzweig, Michel C.

“…More than one year after its inception, the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies by Barnes, Christopher O., West, Anthony P., Huey-Tubman, Kathryn E., Hoffmann, Magnus A.G., Sharaf, Naima G., Hoffman, Pauline R., Koranda, Nicholas, Gristick, Harry B., Gaebler, Christian, Muecksch, Frauke, Lorenzi, Julio C. Cetrulo, Finkin, Shlomo, Hägglöf, Thomas, Hurley, Arlene, Millard, Katrina G., Weisblum, Yiska, Schmidt, Fabian, Hatziioannou, Theodora, Bieniasz, Paul D., Caskey, Marina, Robbiani, Davide F., Nussenzweig, Michel C., Bjorkman, Pamela J.

“…Neutralizing antibody responses to coronaviruses mainly target the receptor-binding domain (RBD) of the trimeric spike. Here, we characterized polyclonal…”
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Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations by Muecksch, Frauke, Weisblum, Yiska, Barnes, Christopher O., Schmidt, Fabian, Schaefer-Babajew, Dennis, Wang, Zijun, C. Lorenzi, Julio C., Flyak, Andrew I., DeLaitsch, Andrew T., Huey-Tubman, Kathryn E., Hou, Shurong, Schiffer, Celia A., Gaebler, Christian, Da Silva, Justin, Poston, Daniel, Finkin, Shlomo, Cho, Alice, Cipolla, Melissa, Oliveira, Thiago Y., Millard, Katrina G., Ramos, Victor, Gazumyan, Anna, Rutkowska, Magdalena, Caskey, Marina, Nussenzweig, Michel C., Bjorkman, Pamela J., Hatziioannou, Theodora, Bieniasz, Paul D.

“…Antibodies elicited by infection accumulate somatic mutations in germinal centers that can increase affinity for cognate antigens. We analyzed 6 independent…”
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Dynamic regulation of T FH selection during the germinal centre reaction by Merkenschlager, Julia, Finkin, Shlomo, Ramos, Victor, Kraft, Julian, Cipolla, Melissa, Nowosad, Carla R, Hartweger, Harald, Zhang, Wenzhu, Olinares, Paul Dominic B, Gazumyan, Anna, Oliveira, Thiago Y, Chait, Brian T, Nussenzweig, Michel C

“…The germinal centre is a dynamic microenvironment in which B cells that express high-affinity antibody variants produced by somatic hypermutation are selected…”
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Dynamic regulation of TFH selection during the germinal centre reaction by Merkenschlager, Julia, Finkin, Shlomo, Ramos, Victor, Kraft, Julian, Cipolla, Melissa, Nowosad, Carla R., Hartweger, Harald, Zhang, Wenzhu, Olinares, Paul Dominic B., Gazumyan, Anna, Oliveira, Thiago Y., Chait, Brian T., Nussenzweig, Michel C.

“…The germinal centre is a dynamic microenvironment in which B cells that express high-affinity antibody variants produced by somatic hypermutation are selected…”
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Dynamic regulation of T.sub.FH selection during the germinal centre reaction by Merkenschlager, Julia, Finkin, Shlomo, Ramos, Victor, Kraft, Julian, Cipolla, Melissa, Nowosad, Carla R, Hartweger, Harald, Zhang, Wenzhu, Olinares, Paul Dominic B, Gazumyan, Anna, Oliveira, Thiago Y, Chait, Brian T, Nussenzweig, Michel C

“…The germinal centre is a dynamic microenvironment in which B cells that express high-affinity antibody variants produced by somatic hypermutation are selected…”
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Transcriptional repression of c-Jun's E3 ubiquitin ligases contributes to c-Jun induction by UV by Anzi, Shira, Finkin, Shlomo, Shaulian, Eitan

“…UV radiation is a major environmental carcinogen. The oncoprotein c-Jun that is required for development of skin cancer is stabilized by UV radiation. The…”
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