Search Results - "Finkielstein, Carla V."

H2S‑Releasing Polymer Micelles for Studying Selective Cell Toxicity by Foster, Jeffrey C, Radzinski, Scott C, Zou, Xianlin, Finkielstein, Carla V, Matson, John B

“…We report the preparation of S-aroylthiooxime (SATO) functionalized amphiphilic block copolymer micelles that release hydrogen sulfide (H2S), a gaseous…”
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The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells by Gotoh, Tetsuya, Vila-Caballer, Marian, Santos, Carlo S, Liu, Jingjing, Yang, Jianhua, Finkielstein, Carla V

“…Human Period 2 (hPer2) is a transcriptional regulator at the core of the circadian clock mechanism that is responsible for generating the negative feedback…”
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The Pro-Inflammatory Chemokines CXCL9, CXCL10 and CXCL11 Are Upregulated Following SARS-CoV-2 Infection in an AKT-Dependent Manner by Callahan, Victoria, Hawks, Seth, Crawford, Matthew A, Lehman, Caitlin W, Morrison, Holly A, Ivester, Hannah M, Akhrymuk, Ivan, Boghdeh, Niloufar, Flor, Rafaela, Finkielstein, Carla V, Allen, Irving Coy, Weger-Lucarelli, James, Duggal, Nisha, Hughes, Molly A, Kehn-Hall, Kylene

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible RNA virus that is the causative agent of the Coronavirus disease 2019…”
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Association of the circadian factor Period 2 to p53 influences p53's function in DNA-damage signaling by Gotoh, Tetsuya, Vila-Caballer, Marian, Liu, Jingjing, Schiffhauer, Samuel, Finkielstein, Carla V

“…Circadian period proteins influence cell division and death by associating with checkpoint components, although their mode of regulation has not been firmly…”
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Vaccine Effectiveness during Outbreak of COVID-19 Alpha (B.1.1.7) Variant in Men’s Correctional Facility, United States by Silverman, Rachel A, Ceci, Alessandro, Cohen, Alasdair, Helmick, Meagan, Short, Erica, Bordwine, Paige, Friedlander, Michael J, Finkielstein, Carla V

“…In April 2021, a COVID-19 outbreak occurred at a correctional facility in rural Virginia, USA. Eighty-four infections were identified among 854 incarcerated…”
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Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein and ubiquitin ligase MDM2 by Liu, JingJing, Zou, Xianlin, Gotoh, Tetsuya, Brown, Anne M, Jiang, Liang, Wisdom, Esther L, Kim, Jae Kyoung, Finkielstein, Carla V

“…The circadian clock relies on posttranslational modifications to set the timing for degradation of core regulatory components, which drives clock progression…”
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Widespread exposure to SARS-CoV-2 in wildlife communities by Goldberg, Amanda R., Langwig, Kate E., Brown, Katherine L., Marano, Jeffrey M., Rai, Pallavi, King, Kelsie M., Sharp, Amanda K., Ceci, Alessandro, Kailing, Christopher D., Kailing, Macy J., Briggs, Russell, Urbano, Matthew G., Roby, Clinton, Brown, Anne M., Weger-Lucarelli, James, Finkielstein, Carla V., Hoyt, Joseph R.

“…Pervasive SARS-CoV-2 infections in humans have led to multiple transmission events to animals. While SARS-CoV-2 has a potential broad wildlife host range, most…”
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Author Correction: Widespread exposure to SARS-CoV-2 in wildlife communities by Goldberg, Amanda R., Langwig, Kate E., Brown, Katherine L., Marano, Jeffrey M., Rai, Pallavi, King, Kelsie M., Sharp, Amanda K., Ceci, Alessandro, Kailing, Christopher D., Kailing, Macy J., Briggs, Russell, Urbano, Matthew G., Roby, Clinton, Brown, Anne M., Weger-Lucarelli, James, Finkielstein, Carla V., Hoyt, Joseph R.

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A Systems Biology Approach Identifies Hidden Regulatory Connections Between the Circadian and Cell-Cycle Checkpoints by Zou, Xianlin, Kim, Dae Wook, Gotoh, Tetsuya, Liu, Jingjing, Kim, Jae Kyoung, Finkielstein, Carla V

“…Circadian rhythms form a self-sustaining, endogenous, time-keeping system that allows organisms to anticipate daily environmental changes. The core of the…”
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Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism by Xiao, Shuyan, Brannon, Mary K., Zhao, Xiaolin, Fread, Kristen I., Ellena, Jeffrey F., Bushweller, John H., Finkielstein, Carla V., Armstrong, Geoffrey S., Capelluto, Daniel G.S.

“…Early endosomes represent the first sorting station for vesicular ubiquitylated cargo. Tollip, through its C2 domain, associates with endosomal…”
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The impact of sulfatide loss on the progress of Alzheimer's disease by Finkielstein, Carla V., Capelluto, Daniel G. S.

“…Experiments carried out using a knockout mice model with deficient levels of ST have revealed that the expression of the ApoE gene is upregulated as a…”
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Mechanisms of Conformational Change for a Replicative Hexameric Helicase of SV40 Large Tumor Antigen by Gai, Dahai, Zhao, Rui, Li, Dawei, Finkielstein, Carla V., Chen, Xiaojiang S.

“…The large tumor antigen (LTag) of simian virus 40, an AAA + protein, is a hexameric helicase essential for viral DNA replication in eukaryotic cells. LTag…”
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Biophysical and Molecular-Dynamics Studies of Phosphatidic Acid Binding by the Dvl-2 DEP Domain by Capelluto, Daniel G.S., Zhao, Xiaolin, Lucas, Andrew, Lemkul, Justin A., Xiao, Shuyan, Fu, Xiangping, Sun, Furong, Bevan, David R., Finkielstein, Carla V.

“…The Wnt-dependent, β-catenin-independent pathway modulates cell movement and behavior. A downstream regulator of this signaling pathway is Dishevelled (Dvl),…”
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Moderate Exercise Prevents Functional Remodeling of the Anterior Pituitary Gland in Diet-Induced Insulin Resistance in Rats: Role of Oxidative Stress and Autophagy by Mercau, María E, Repetto, Esteban M, Perez, Matías N, Martinez Calejman, Camila, Sanchez Puch, Silvia, Finkielstein, Carla V, Cymeryng, Cora B

“…A sustained elevation of glucocorticoid production, associated with the establishment of insulin resistance (IR) could add to the deleterious effects of the IR…”
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A Novel Heme-Regulatory Motif Mediates Heme-Dependent Degradation of the Circadian Factor Period 2 by Yang, Jianhua, Kim, Kevin D., Lucas, Andrew, Drahos, Karen E., Santos, Carlo S., Mury, Sean P., Capelluto, Daniel G. S., Finkielstein, Carla V.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Ligand binding reveals a role for heme in translationally-controlled tumor protein dimerization by Lucas, Andrew T, Fu, Xiangping, Liu, JingJing, Brannon, Mary K, Yang, Jianhua, Capelluto, Daniel G S, Finkielstein, Carla V

“…The translationally-controlled tumor protein (TCTP) is a highly conserved, ubiquitously expressed, abundant protein that is broadly distributed among…”
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Three Amino Acid Mutations (F51L, T59A, and S390L) in the Capsid Protein of the Hepatitis E Virus Collectively Contribute to Virus Attenuation by CORDOBA, Laura, HUANG, Yao-Wei, OPRIESSNIG, Tanja, HARRAL, Kylie K, BEACH, Nathan M, FINKIELSTEIN, Carla V, EMERSON, Suzanne U, MENG, Xiang-Jin

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cell Migration and Signaling Specificity Is Determined by the Phosphatidylserine Recognition Motif of Rac1 by Finkielstein, Carla V., Overduin, Michael, Capelluto, Daniel G.S.

“…The Rho guanosine triphosphatases (GTPases) control cell shape and motility and are frequently overexpressed during malignant growth. These proteins act as…”
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Circadian clock gene polymorphisms implicated in human pathologies by Janoski, Jesse R., Aiello, Ignacio, Lundberg, Clayton W., Finkielstein, Carla V.

“…In addition to circadian rhythms, circadian genes play pivotal roles in myriad signaling pathways. Consequently, their dysregulation contributes to the onset…”
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Modeling the Relationship between the p53 C-Terminal Domain and Its Binding Partners Using Molecular Dynamics by Allen, William J, Capelluto, Daniel G. S, Finkielstein, Carla V, Bevan, David R

“…Fifty percent of all cancer cases result from mutations of the TP53 gene, which encodes the tumor suppressor p53, and it is hypothesized that the p53-mediated…”
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