Search Results - "Finkelstein, J D"

The metabolism of homocysteine: pathways and regulation by Finkelstein, J D

“…Two pathways, the methionine cycle and transsulfuration, account for virtually all methionine metabolism in mammals. Every tissue possesses the methionine…”
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Pathways and regulation of homocysteine metabolism in mammals by Finkelstein, J D

“…Two intersecting pathways, the methionine cycle and the transsulfuration sequence, compose the mechanisms for homocysteine metabolism in mammals. The…”
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Glycine N‐methyltransferase deficiency: A novel inborn error causing persistent isolated hypermethioninaemia by Mudd, S. H., Cerone, R., Schiaffino, M. C., Fantasia, A. R., Minniti, G., Caruso, U., Lorini, R., Watkins, D., Matiaszuk, N., Rosenblatt, D. S., Schwahn, B., Rozen, R., LeGros, L., Kotb, M., Capdevila, A., Luka, Z., Finkelstein, J. D., Tangerman, A., Stabler, S. P., Allen, R. H., Wagner, C.

“…This paper reports clinical and metabolic studies of two Italian siblings with a novel form of persistent isolated hypermethioninaemia, i.e. abnormally…”
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Homocysteine: A History in Progress by Finkelstein, James D.

“…This paper shows that the linkage between basic science and clinical research has characterized the field of sulfur amino acid metabolism since 1810, when…”
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Homocysteine and Its Disulfide Derivatives: A Suggested Consensus Terminology by Mudd, S Harvey, Finkelstein, James D, Refsum, Helga, Ueland, Per M, Malinow, M René, Lentz, Steven R, Jacobsen, Donald W, Brattström, Lars, Wilcken, Bridget, Wilcken, David E. L, Blom, Henk J, Stabler, Sally P, Allen, Robert H, Selhub, Jacob, Rosenberg, Irwin H

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Maternal hyperhomocysteinemia: a risk factor for neural-tube defects? by Steegers-Theunissen, R P, Boers, G H, Trijbels, F J, Finkelstein, J D, Blom, H J, Thomas, C M, Borm, G F, Wouters, M G, Eskes, T K

“…The maternal vitamin status, especially of folate, is involved in the pathogenesis of neural-tube defects (NTDs). Maternal folate administration can prevent…”
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Methionine metabolism in mammals. Adaptation to methionine excess by Finkelstein, J D, Martin, J J

“…We conducted a systematic evaluation of the effects of increasing levels of dietary methionine on the metabolites and enzymes of methionine metabolism in rat…”
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Methionine metabolism in mammals. Distribution of homocysteine between competing pathways by Finkelstein, J D, Martin, J J

“…Using an in vitro system which contained enzymes, substrates, and other reactants at concentrations which approximated the in vivo conditions in rat liver, we…”
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Methionine metabolism in mammals. The methionine-sparing effect of cystine by Finkelstein, J D, Martin, J J, Harris, B J

“…Cystine can replace approximately 70% of the dietary requirement for methionine. We used standard enzyme assays, determinations of the hepatic concentrations…”
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Methionine-sparing effect of cystine in human subjects by Finkelstein, J D

“…An editorial examines the methionine-sparing effect of cystine in human subjects. Earliest research on cystine had only pertained to animal metabolism, so its…”
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Homocysteine by Finkelstein, James D, Martin, John J

“…Homocysteine does not occur in the diet but it is an essential intermediate in normal mammalian metabolism of methionine. Each compound, methionine or…”
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Transsulfuration in an adult with hepatic methionine adenosyltransferase deficiency by GAHL, W. A, BERNARDINI, I, FINKELSTEIN, J. D, TANGERMAN, A, MARTIN, J. J, BLOM, H. J, MULLEN, K. D, MUDD, S. H

“…We investigated sulfur and methyl group metabolism in a 31-yr-old man with partial hepatic methionine adenosyltransferase (MAT) deficiency. The patient's…”
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Effect of dietary cystine on methionine metabolism in rat liver by Finkelstein, J D, Martin, J J, Harris, B J

“…Cystine supplementation of adequate diets resulted in significantly higher hepatic levels of betaine-homocysteine methyltransferase. Other changes occurred but…”
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Persistent hypermethioninaemia with dominant inheritance by Blom, H. J., Davidson, A. J., Finkelstein, J. D., Luder, A. S., Bernardini, I., Martin, J. J., Tangerman, A., Trijbels, J. M. F., Mudd, S. H., Goodman, S. I., Gahl, W. A.

“…Summary A clinically benign form of persistent hypermethioninaemia with probable dominant inheritance was demonstrated in three generations of one family…”
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Hepatic methionine adenosyltransferase deficiency in a 31-year-old man by GAHL, W. A, FINKELSTEIN, J. D, MULLEN, K. D, BERNARDINI, I, MARTIN, J. J, BACKLUND, P, ISHAK, K. G, HOOFNAGLE, J. H, MUDD, S. H

“…A 31-year-old man with hepatic methionine adenosyltransferase (MAT) deficiency was evaluated for an odd odor to his breath. He had no other symptoms. Plasma…”
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Effect of nicotinamide on methionine metabolism in rat liver by Finkelstein, J D, Martin, J J, Harris, B

“…To test the response to increased utilization of methyl groups, we administered large dosages of nicotinamide to rats fed an adequate diet that contained…”
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Regulation of hepatic betaine-homocysteine methyltransferase by dietary betaine by Finkelstein, J D, Martin, J J, Harris, B J, Kyle, W E

“…The level of betaine-homocysteine methyltransferase increases in the livers of rats fed diets supplemented with betaine or choline. The increase occurs within…”
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Type B hepatitis after needle-stick exposure: prevention with hepatitis B immune globulin. Final report of the Veterans Administration Cooperative Study by Seeff, L B, Wright, E C, Zimmerman, H J, Alter, H J, Dietz, A A, Felsher, B F, Finkelstein, J D, Garcia-Pont, P, Gerin, J L, Greenlee, H B, Hamilton, J, Holland, P V, Kaplan, P M, Kiernan, T, Koff, R S, Leevy, C M, McAuliffe, V J, Nath, N, Purcell, R H, Schiff, E R, Schwartz, C C, Tamburro, C H, Vlahcevic, Z, Zemel, R, Zimmon, D S

“…Hepatitis B immune globulin (HBIG) and immune serum globulin (ISG) were examined in a randomized, double-blind trial to assess their relative efficacies in…”
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Methionine metabolism in mammals: concentration of metabolites in rat tissues by Finkelstein, J D, Kyle, W E, Harris, B J, Martin, J J

“…We have evaluated factors which regulate the content of methionine, adenosylmethionine, adenosylhomocysteine, cystine, cysteine and acid-soluble thiols in rat…”
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Trans-sulfuration in mammals. The methionine-sparing effect of cystine by Finkelstein, J D, Mudd, S H

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