Search Results - "Finkel, T"
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Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Published in Nature metabolism (01-06-2022)“…Multiple roles of reactive oxygen species (ROS) and their consequences for health and disease are emerging throughout biological sciences. This development has…”
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Reactive Oxygen Species and Signal Transduction
Published in IUBMB life (01-07-2001)“…Increasing evidence suggests a role for intracellular reactive oxygen species (ROS) as mediators of normal and pathological signal transduction pathways. In…”
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Signal transduction by reactive oxygen species in non-phagocytic cells
Published in Journal of leukocyte biology (01-03-1999)“…A growing body of evidence suggests a potential role for oxygen‐derived radicals such as superoxide anions and hydrogen peroxide as intracellular signaling…”
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Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes
Published in Nature medicine (01-02-1995)“…Although 13 years have passed since identification of human immunodeficiency virus-1 (HIV-1) as the cause of AIDS, we do not yet know how HIV kills its primary…”
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Role for Mitochondrial Oxidants as Regulators of Cellular Metabolism
Published in Molecular and Cellular Biology (01-10-2000)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model
Published in Cancer gene therapy (01-12-2014)“…Melanoma is the most deadly type of skin cancer, constituting annually ∼75% of all cutaneous cancer-related deaths due to metastatic spread. Currently, because…”
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Biochemical mechanisms of HIV induced T cell apoptosis
Published in Cell death and differentiation (01-02-2001)Get full text
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The association of PTPN22 rs2476601 with juvenile idiopathic arthritis is specific to females
Published in Genes and immunity (01-10-2015)“…A preponderance of females develop autoimmune disease, including juvenile idiopathic arthritis (JIA), yet the reason for this bias remains elusive. Evidence…”
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ENDOTHELIAL AUTOPHAGY IS ESSENTIAL FOR VASCULAR LIPID HOMEOSTASIS
Published in Canadian journal of cardiology (01-10-2015)Get full text
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Reactive Oxygen Species are Downstream Mediators of p53-Dependent Apoptosis
Published in Proceedings of the National Academy of Sciences - PNAS (15-10-1996)“…Reactive oxygen species (ROS) have been implicated as potential modulators of apoptosis. Conversely, experiments under hypoxic conditions have suggested that…”
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Identification of Oxidant-Sensitive Proteins: TNF-α Induces Protein Glutathiolation
Published in Biochemistry (Easton) (12-09-2000)“…Reactive oxygen species are thought to play a role in a variety of physiologic and pathophysiological processes. One possible mediator of oxidant effects at…”
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ENDOTHELIAL AUTOPHAGY REGULATES CHOLESTEROL TRANSPORT AND IS A NOVEL REGULATOR OF ATHEROSCLEROSIS
Published in Canadian journal of cardiology (01-10-2014)Get full text
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Oxidant signals and oxidative stress
Published in Current opinion in cell biology (01-04-2003)“…Although oxidants clearly possess the capacity to behave in a random and destructive fashion, growing evidence suggests that in many instances the production…”
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Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis
Published in The Journal of experimental medicine (01-10-1992)“…During human immunodeficiency virus (HIV) infection there is a profound and selective decrease in the CD4+ population of T lymphocytes. The mechanism of this…”
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Chronic parvovirus B19 infection and systemic necrotising vasculitis: opportunistic infection or aetiological agent?
Published in The Lancet (British edition) (21-05-1994)“…We describe three patients who had infection with human parvovirus B19 in association with new-onset systemic necrotising vasculitis syndromes, two with…”
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Radical medicine: treating ageing to cure disease
Published in Nature reviews. Molecular cell biology (01-12-2005)“…The incidence of many diseases rises sharply with age. Although clearly separable, ageing and certain age-related diseases might share common mechanisms…”
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Myocyte hypertrophy: the long and winding RhoA'd
Published in The Journal of clinical investigation (01-06-1999)Get full text
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The role of infection in restenosis and atherosclerosis: focus on cytomegalovirus
Published in The Lancet (British edition) (01-11-1996)Get more information
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Oxygen radicals and signaling
Published in Current opinion in cell biology (01-04-1998)“…Recent evidence suggests that reactive oxygen species, such as superoxide anions and hydrogen peroxide, function as intracellular second messengers. This…”
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728 BRCA1 induces cardiac protection through a P53-dependent pathway
Published in Canadian journal of cardiology (01-09-2011)Get full text
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