Search Results - "Fingleton, James"

Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report by McDonald, Vanessa M, Fingleton, James, Agusti, Alvar, Hiles, Sarah A, Clark, Vanessa L, Holland, Anne E, Marks, Guy B, Bardin, Philip P, Beasley, Richard, Pavord, Ian D, Wark, Peter A B, Gibson, Peter G

“…"Treatable traits" have been proposed as a new paradigm for the management of airway diseases, particularly complex disease, which aims to apply personalised…”
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Metabolomic changes related to airway inflammation, asthma pathogenesis and systemic activity following inhaled fluticasone furoate/vilanterol: a randomized controlled trial by Daley-Yates, Peter, Keppler, Brian, Baines, Amanda, Bardsley, George, Fingleton, James

“…Fluticasone furoate/vilanterol trifenatate (FF/VI) is an inhaled therapy for the treatment of asthma, with a prolonged duration of anti-inflammatory and…”
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ICS-formoterol reliever versus ICS and short-acting β2-agonist reliever in asthma: a systematic review and meta-analysis by Hatter, Lee, Bruce, Pepa, Braithwaite, Irene, Holliday, Mark, Fingleton, James, Weatherall, Mark, Beasley, Richard

“…BACKGROUNDThe Global Initiative for Asthma recommends as-needed inhaled corticosteroid (ICS)-formoterol as an alternative to maintenance ICS plus short-acting…”
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Serum periostin in obstructive airways disease by Fingleton, James, Braithwaite, Irene, Travers, Justin, Bowles, Darren, Strik, Rianne, Siebers, Rob, Holweg, Cecile, Matthews, John, Weatherall, Mark, Beasley, Richard

“…Serum periostin is a potential biomarker of response to therapies that target type 2 inflammation in asthma. The objectives of this study were to describe: 1)…”
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Long-Term Outcomes of External Repair as a Rescue Operation for Atrioventricular Groove Disruption by Dobrilovic, Nikola, MD, Raman, Jaishankar, MD, PhD, Fingleton, James G., MD, Maslow, Andrew, MD, Singh, Arun K., MD

“…Background Atrioventricular groove disruption (AVGD) is an uncommon but lethal complication of mitral valve operations associated with mortality approaching…”
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Oxygen versus air-driven nebulisers for exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial by Bardsley, George, Pilcher, Janine, McKinstry, Steven, Shirtcliffe, Philippa, Berry, James, Fingleton, James, Weatherall, Mark, Beasley, Richard

“…In exacerbations of chronic obstructive pulmonary disease, administration of high concentrations of oxygen may cause hypercapnia and increase mortality…”
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Anti-inflammatory duration of action of fluticasone furoate/vilanterol trifenatate in asthma: a cross-over randomised controlled trial by Bardsley, George, Daley-Yates, Peter, Baines, Amanda, Kempsford, Rodger, Williams, Mathew, Mallon, Tony, Braithwaite, Irene, Riddell, Kylie, Joshi, Shashidhar, Bareille, Philippe, Beasley, Richard, Fingleton, James

“…Fluticasone furoate/Vilanterol trifenatate (FF/VI) is an inhaled corticosteroid/long-acting beta-agonist combination with a prolonged bronchodilator duration…”
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Type 2 Biomarkers and Prediction of Future Exacerbations and Lung Function Decline in Adult Asthma by Semprini, Ruth, Williams, Mathew, Semprini, Alex, McDouall, Alice, Fingleton, James, Holweg, Cecile, Weatherall, Mark, Beasley, Richard, Braithwaite, Irene

“…Type 2 biomarkers that predict both likelihood of future severe exacerbations and response to mAb therapy in asthma would be useful clinically in identifying…”
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Impaired coronary contraction to phenylephrine after cardioplegic arrest in diabetic patients by Sellke, Nicholas, Gordon, Caroline, Lawandy, Isabella, Gorvitovskaia, Anastassia Y., Scrimgeour, Laura A., Fingleton, James G., Sellke, Frank W., Feng, Jun

“…We have previously found that hyperkalemic cardioplegic arrest in the setting of cardiopulmonary bypass (CP/CPB) is associated with impairment of the coronary…”
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Rhinothermy delivered by nasal high flow therapy in the treatment of the common cold: a randomised controlled trial by Bird, Grace, Braithwaite, Irene, Harper, James, Koorevaar, Iris, van den Berg, Marthe, Maijers, Ingrid, Kearns, Nethmi, Dilcher, Meik, Jennings, Lance, Fingleton, James, Shortt, Nick, Weatherall, Mark, Beasley, Richard

“…BackgroundThe common cold is the most common infectious disease affecting humans and has a substantial economic impact on society. Human rhinoviruses, which…”
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Changes in Microvascular Reactivity After Cardiopulmonary Bypass in Patients With Poorly Controlled Versus Controlled Diabetes by JUN FENG, YUHONG LIU, CHU, Louis M, SINGH, Arun K, DOBRILOVIC, Nikola, FINGLETON, James G, CLEMENTS, Richard T, BIANCHI, Cesario, SELLKE, Frank W

“…We investigated the effects of cardiopulmonary bypass (CPB) on peripheral arteriolar reactivity and associated signaling pathways in poorly controlled (UDM),…”
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Long-term survival after use of internal thoracic artery in octogenarians is gender related by Singh, Arun K., MD, FRCS(C), Maslow, Andrew D., MD, Machan, Jason T., PhD, Fingleton, James G., MD, Feng, William C., MD, Schwartz, Carl, MD, Rotenberg, Fred A., MD, Bert, Arthur A., MD

“…Abstract Objective The goal of this study is to assess the benefits of a left internal thoracic artery as a bypass conduit in octogenarians undergoing elective…”
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Asthma control with ICS-formoterol reliever versus maintenance ICS and SABA reliever therapy: a post hoc analysis of two randomised controlled trials by Hatter, Lee, Houghton, Claire, Bruce, Pepa, Holliday, Mark, Eathorne, Allie, Pavord, Ian, Reddel, Helen K, Hancox, Robert J, Braithwaite, Irene, Oldfield, Karen, Papi, Alberto, Weatherall, Mark, Beasley, Richard, Corin, Andrew, Fingleton, James, Hall, Daniela, Mane, Saras, Martindale, John, Sabbagh, Doñah, Sparks, Jenny, Vohlidkova, Alexandra

“…BackgroundIn randomised controlled trials, as-needed inhaled corticosteroid (ICS)-formoterol reliever therapy reduces severe exacerbation risk compared with…”
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Serum periostin levels following small bone fractures, long bone fractures and joint replacements: an observational study by Varughese, Rachel, Semprini, Ruth, Munro, Claire, Fingleton, James, Holweg, Cecile, Weatherall, Mark, Beasley, Richard, Braithwaite, Irene

“…In asthma, serum periostin may potentially be used as a biomarker in the management of patients with Type-2 eosinophilic airway inflammation. However, serum…”
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Serum periostin levels in adults of Chinese descent: an observational study by Tan, Evan, Varughese, Rachel, Semprini, Ruth, Montgomery, Barney, Holweg, Cecile, Olsson, Julie, Caswell-Smith, Rachel, Fingleton, James, Weatherall, Mark, Beasley, Richard, Braithwaite, Irene

“…Periostin has been shown to be a marker of Type 2 airway inflammation, associated with airway eosinophilia. It has a potential role in identifying asthmatics…”
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Treatment responsiveness of phenotypes of symptomatic airways obstruction in adults by Fingleton, James, PhD, Travers, Justin, MBChB, Williams, Mathew, Dip Ex Sci, Charles, Thomas, DipSM, Bowles, Darren, MBChB, Strik, Rianne, BSc, Shirtcliffe, Philippa, MBChB, Weatherall, Mark, MBChB, Beasley, Richard, DSc

“…Background Asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous disorders encompassing different phenotypes of airflow obstruction, which…”
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Magnetic Resonance Angiography Demonstrating Active Spontaneous Intercostal Bleeding by Dobrilovic, Nikola, MD, Sadiq, Immad, MD, Vognar, Lidia A., MD, Fingleton, James G., MD

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Midterm outcomes of patients undergoing aortic valve replacement after previous coronary artery bypass grafting by Dobrilovic, Nikola, Fingleton, James G., Maslow, Andrew, Machan, Jason, Feng, William, Casey, Paula, Sellke, Frank W., Singh, Arun K.

“…OBJECTIVES Redo cardiac surgery for aortic valve replacement (AVR) after previous coronary artery bypass grafting (CABG) is technically challenging and carries…”
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Efficacy of Micromobile Foot Compression Device in Increasing Lower Limb Venous Blood Flow by Charles, Thomas, Mackintosh, Stephen, Fingleton, James, Braithwaite, Irene, Weatherall, Mark, Beasley, Richard

“…Background. A novel, micromobile foot compression device (MMC) has been developed to reduce the risk of venous thromboembolism associated with prolonged seated…”
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Treatable traits of chronic airways disease by Fingleton, James, Hardy, Jo, Beasley, Richard

“…PURPOSE OF REVIEWTo describe the rationale on which the treatable traits approach to the management of airways disease is based and the issues that need to be…”
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