Search Results - "Fingerlin, Tasha E"

CT Scan Findings of Probable Usual Interstitial Pneumonitis Have a High Predictive Value for Histologic Usual Interstitial Pneumonitis by Chung, Jonathan H., MD, Chawla, Ashish, MD, Peljto, Anna L., PhD, Cool, Carlyne D., MD, Groshong, Steve D., MD, Talbert, Janet L., MS, McKean, David F., BS, Brown, Kevin K., MD, FCCP, Fingerlin, Tasha E., PhD, Schwarz, Marvin I., MD, FCCP, Schwartz, David A., MD, Lynch, David A., MBBS

“…The current usual interstitial pneumonitis (UIP)/idiopathic pulmonary fibrosis CT scan classification system excludes probable UIP as a diagnostic category. We…”
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MUC5B Promoter Polymorphism and Interstitial Lung Abnormalities by Hunninghake, Gary M, Hatabu, Hiroto, Okajima, Yuka, Gao, Wei, Dupuis, Josée, Latourelle, Jeanne C, Nishino, Mizuki, Araki, Tetsuro, Zazueta, Oscar E, Kurugol, Sila, Ross, James C, San José Estépar, Raúl, Murphy, Elissa, Steele, Mark P, Loyd, James E, Schwarz, Marvin I, Fingerlin, Tasha E, Rosas, Ivan O, Washko, George R, O'Connor, George T, Schwartz, David A

“…Variants in the gene encoding mucin 5B ( MUC5B ) have been associated with interstitial fibrosis. This study shows a relationship between the presence of the…”
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Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease by Poole, Alex, MS, Urbanek, Cydney, BS, Eng, Celeste, BS, Schageman, Jeoffrey, BS, Jacobson, Sean, MS, O'Connor, Brian P., PhD, Galanter, Joshua M., MD, Gignoux, Christopher R., PhD, Roth, Lindsey A., MA, Kumar, Rajesh, MD, Lutz, Sharon, PhD, Liu, Andrew H., MD, Fingerlin, Tasha E., PhD, Setterquist, Robert A., PhD, Burchard, Esteban G., MD, Rodriguez-Santana, Jose, MD, Seibold, Max A., PhD

“…Background Bronchial airway expression profiling has identified inflammatory subphenotypes of asthma, but the invasiveness of this technique has limited its…”
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Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis by Yang, Ivana V, Coldren, Christopher D, Leach, Sonia M, Seibold, Max A, Murphy, Elissa, Lin, Jia, Rosen, Rachel, Neidermyer, Amanda J, McKean, David F, Groshong, Steve D, Cool, Carlyne, Cosgrove, Gregory P, Lynch, David A, Brown, Kevin K, Schwarz, Marvin I, Fingerlin, Tasha E, Schwartz, David A

“…Idiopathic pulmonary fibrosis (IPF) is an untreatable lung disease with a median survival of only 3-5 years that is diagnosed using a combination of clinical,…”
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Spatially distinct molecular patterns of gene expression in idiopathic pulmonary fibrosis by Blumhagen, Rachel Z, Kurche, Jonathan S, Cool, Carlyne D, Walts, Avram D, Heinz, David, Fingerlin, Tasha E, Yang, Ivana V, Schwartz, David A

“…Idiopathic pulmonary fibrosis (IPF) is a heterogeneous disease that is pathologically characterized by areas of normal-appearing lung parenchyma, active…”
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Genetics of Sarcoidosis by Fingerlin, Tasha E., PhD, Hamzeh, Nabeel, MD, Maier, Lisa A., MD, MSPH

“…Sarcoidosis is a disease with highly variable presentation and progression; although it is hypothesized that disease phenotype is related to genetic variation,…”
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Refractory neutrophilic asthma and ciliary genes by Guntur, Vamsi P., Manka, Laurie A., Moore, Camille M., Wynn, Elizabeth, Vladar, Eszter K., Alam, Rafeul, Pham, Tuyet-Hang, Fingerlin, Tasha E., Martin, Richard J.

“…Refractory asthma (RA) remains poorly controlled, resulting in high health care utilization despite guideline-based therapies. Patients with RA manifest higher…”
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Genome-wide association study identifies multiple HLA loci for sarcoidosis susceptibility by Liao, Shu-Yi, Jacobson, Sean, Hamzeh, Nabeel Y, Culver, Daniel A, Barkes, Briana Q, Mroz, Margarita, Macphail, Kristyn, Pacheco, Karin, Patel, Divya C, Wasfi, Yasmine S, Koth, Laura L, Langefeld, Carl D, Leach, Sonia M, White, Elizabeth, Montgomery, Courtney, Maier, Lisa A, Fingerlin, Tasha E

“…Abstract Sarcoidosis is a complex systemic disease. Our study aimed to (1) identify novel alleles associated with sarcoidosis susceptibility; (2) provide an…”
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The MUC5B Promoter Polymorphism Is Associated With Idiopathic Pulmonary Fibrosis in a Mexican Cohort but Is Rare Among Asian Ancestries by Peljto, Anna L., DrPH, Selman, Moises, MD, FCCP, Kim, Dong Soon, MD, Murphy, Elissa, MS, Tucker, Laura, BS, Pardo, Annie, PhD, Lee, Jung Su, MD, Ji, Wonjun, MD, Schwarz, Marvin I., MD, FCCP, Yang, Ivana V., PhD, Schwartz, David A., MD, Fingerlin, Tasha E., PhD

“…BACKGROUND Polymorphisms in the MUC5B promoter, TOLLIP , and nine additional genetic loci have been associated with idiopathic pulmonary fibrosis (IPF) within…”
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Incidence and Progression of Fibrotic Lung Disease in an At-Risk Cohort by Steele, Mark P, Peljto, Anna L, Mathai, Susan K, Humphries, Stephen, Bang, Tami J, Oh, Andrea, Teague, Shawn, Cicchetti, Giuseppe, Sigakis, Christopher, Kropski, Jonathan A, Loyd, James E, Blackwell, Timothy S, Brown, Kevin K, Schwarz, Marvin I, Warren, Rachel A, Powers, Julia, Walts, Avram D, Markin, Cheryl, Fingerlin, Tasha E, Yang, Ivana V, Lynch, David A, Lee, Joyce S, Schwartz, David A

“…Relatives of patients with familial interstitial pneumonia (FIP) are at increased risk for pulmonary fibrosis and develop preclinical pulmonary fibrosis…”
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A comparison of methods for multiple degree of freedom testing in repeated measures RNA-sequencing experiments by Wynn, Elizabeth A, Vestal, Brian E, Fingerlin, Tasha E, Moore, Camille M

“…As the cost of RNA-sequencing decreases, complex study designs, including paired, longitudinal, and other correlated designs, become increasingly feasible…”
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Genetic and Environmental Determinants of 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels in Hispanic and African Americans by Engelman, Corinne D., Fingerlin, Tasha E., Langefeld, Carl D., Hicks, Pamela J., Rich, Stephen S., Wagenknecht, Lynne E., Bowden, Donald W., Norris, Jill M.

“…Context: Vitamin D deficiency is associated with many adverse health outcomes, yet little is known about the genetic epidemiology of vitamin D or its…”
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Dual RNA-seq reveals viral infections in asthmatic children without respiratory illness which are associated with changes in the airway transcriptome by Wesolowska-Andersen, Agata, Everman, Jamie L, Davidson, Rebecca, Rios, Cydney, Herrin, Rachelle, Eng, Celeste, Janssen, William J, Liu, Andrew H, Oh, Sam S, Kumar, Rajesh, Fingerlin, Tasha E, Rodriguez-Santana, Jose, Burchard, Esteban G, Seibold, Max A

“…Respiratory illness caused by viral infection is associated with the development and exacerbation of childhood asthma. Little is known about the effects of…”
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Genome‐Wide Association Meta‐Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci by McIntosh, Laura A., Marion, Miranda C., Sudman, Marc, Comeau, Mary E., Becker, Mara L., Bohnsack, John F., Fingerlin, Tasha E., Griffin, Thomas A., Haas, J. Peter, Lovell, Daniel J., Maier, Lisa A., Nigrovic, Peter A., Prahalad, Sampath, Punaro, Marilynn, Rosé, Carlos D., Wallace, Carol A., Wise, Carol A., Moncrieffe, Halima, Howard, Timothy D., Langefeld, Carl D., Thompson, Susan D.

“…Objective Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease and has a strong genomic component. To date, JIA genetic…”
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Occupational and environmental exposures in the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) study by Ryan, Sarah M., Mroz, Margaret M., Herzog, Erica L., Ryu, Changwan, Fingerlin, Tasha E., Maier, Lisa A., Gulati, Mridu

“…Sarcoidosis is a granulomatous disorder thought to be caused by exposures in genetically susceptible individuals. This study investigated whether specific…”
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Clinical phenotyping in sarcoidosis using cluster analysis by Lin, Nancy W, Arbet, Jaron, Mroz, Margaret M, Liao, Shu-Yi, Restrepo, Clara I, Mayer, Annyce S, Li, Li, Barkes, Briana Q, Schrock, Sarah, Hamzeh, Nabeel, Fingerlin, Tasha E, Carlson, Nichole E, Maier, Lisa A

“…Most phenotyping paradigms in sarcoidosis are based on expert opinion; however, no paradigm has been widely adopted because of the subjectivity in…”
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Longitudinal changes in DNA methylation during the onset of islet autoimmunity differentiate between reversion versus progression of islet autoimmunity by Carry, Patrick M, Vanderlinden, Lauren A, Johnson, Randi K, Buckner, Teresa, Steck, Andrea K, Kechris, Katerina, Yang, Ivana V, Fingerlin, Tasha E, Fiehn, Oliver, Rewers, Marian, Norris, Jill M

“…Type 1 diabetes (T1D) is preceded by a heterogenous pre-clinical phase, islet autoimmunity (IA). We aimed to identify pre vs. post-IA seroconversion (SV)…”
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CT Imaging Phenotypes of Pulmonary Fibrosis in the MUC5B Promoter Site Polymorphism by Chung, Jonathan H., MD, Peljto, Anna L., PhD, Chawla, Ashish, MD, Talbert, Janet L., MS, McKean, David F., MS, Rho, Byung-Hak, MD, Fingerlin, Tasha E., PhD, Schwarz, Marvin I., MD, Schwartz, David A., MD, Lynch, David A., MBBS

“…Background To determine the effect of the MUC5B promoter polymorphism (rs35705950) on the CT imaging appearance of pulmonary fibrosis. Methods High-resolution…”
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Blood mRNA biomarkers distinguish variable systemic and sputum inflammation at treatment initiation of inhaled antibiotics in cystic fibrosis: A prospective non-randomized trial by Caceres, Silvia M, Sanders, Linda A, Rysavy, Noel M, Poch, Katie R, Jones, Caroline R, Pickard, Kyle, Fingerlin, Tasha E, Marcus, Roland A, Malcolm, Kenneth C, Taylor-Cousar, Jennifer L, Nichols, David P, Nick, Jerry A, Strand, Matthew, Saavedra, Milene T

“…Inhaled antibiotics control chronic airway infection and maintain respiratory health in cystic fibrosis (CF). Given variation in patient responses to inhaled…”
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The Pulmonary Fibrosis-Associated MUC5B Promoter Polymorphism Does Not Influence the Development of Interstitial Pneumonia in Systemic Sclerosis by Peljto, Anna L., DrPH, Steele, Mark P., MD, FCCP, Fingerlin, Tasha E., PhD, Hinchcliff, Monique E., MD, Murphy, Elissa, MS, Podlusky, Sofia, BA, Carns, Mary, MS, Schwarz, Marvin, MD, FCCP, Varga, John, MD, Schwartz, David A., MD

“…Background More than 80% of patients with systemic sclerosis (SSc) develop lung involvement, most commonly interstitial pneumonia (IP). We recently identified…”
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