Search Results - "Fingar, V H"

Analysis of acute vascular damage after photodynamic therapy using benzoporphyrin derivative (BPD) by FINGAR, V. H, KIK, P. K, HAYDON, P. S, CERRITO, P. B, TSENG, M, ABANG, E, WIEMAN, T. J

“…Benzoporphyrin derivative monoacid ring A (BPD-MA, verteporfin) is currently under investigation as a photosensitizer for photodynamic therapy (PDT). Since BPD…”
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The role of microvascular damage in photodynamic therapy : the effect of treatment on vessel constriction, permeability, and leukocyte adhesion by FINGAR, V. H, JEFFERY WIEMAN, T, WIEHLE, S. A, CERRITO, P. B

“…Intravital microscopy of the rat cremaster muscle was used to evaluate changes in vessel constriction, vessel permeability, and leukocyte adhesion during and…”
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The effects of thromboxane inhibitors on the microvascular and tumor response to photodynamic therapy by Fingar, V H, Siegel, K A, Wieman, T J, Doak, K W

“…Vascular stasis and tissue ischemia are known to cause tumor cell death in several experimental models after photodynamic therapy (PDT); however, the…”
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Relationship of tumor hypoxia and response to photodynamic treatment in an experimental mouse tumor by HENDERSON, B. W, FINGAR, V. H

“…The relationship between tumor oxygenation and the effectiveness of photodynamic therapy (PDT) was studied in vitro and in vivo using the RIF mouse tumor…”
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Role of thromboxane and prostacyclin release on photodynamic therapy-induced tumor destruction by FINGAR, V. H, WIEMAN, T. J, WEBER DOAK, K

“…Thromboxane and prostacyclin levels in serum were measured following photodynamic therapy (PDT) to assess the role of these vasoactive agents on vascular…”
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Photodynamic therapy using mono-L-aspartyl chlorin e6 (Npe6) for the treatment of cutaneous disease: a Phase I clinical study by TABER, S. W, FINGAR, V. H, COOTS, C. T, WIEMAN, T. J

“…The activity of a new photosensitizer, mono-L-aspartyl chlorin e6 (Npe6), was assessed in an ascending dose Phase I study for patients with superficial tumor…”
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In Vivo and In Vitro Photodynamic Studies with Benzochlorin Iminium Salts Delivered by a Lipid Emulsion by Garbo, G. M., Fingar, V. H., Wieman, T. J., III, E. B. Noakes, Haydon, P. S., Cerrito, P. B., Kessel, D. H., Morgan, A. R.

“…Benzochlorin iminium salts (Bis) are hydrophobic photosensitizers based on an octaethylbenzochlorin nucleus that absorb in the near‐IR region of the visible…”
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Photodynamic therapy using a protoporphyrinogen oxidase inhibitor by FINGAR, V. H, WIEMAN, T. J, MCMAHON, K. S, HAYDON, P. S, HALLING, B. P, YUHAS, D. A, WINKELMAN, J. W

“…The use of endogenously created porphyrins as an alternative to photosensitizer injection for photodynamic therapy is a rapidly evolving area of study. One…”
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The effects of photodynamic therapy using differently substituted zinc phthalocyanines on vessel constriction, vessel leakage and tumor response by Fingar, V H, Wieman, T J, Karavolos, P S, Doak, K W, Ouellet, R, van Lier, J E

“…The effects of four different zinc phthalocyanines were studied during and after photodynamic therapy (PDT). Measurements of vessel constriction, vessel…”
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Effect of photodynamic therapy on blood flow in normal and tumor vessels by Wieman, T J, Mang, T S, Fingar, V H, Hill, T G, Reed, M W, Corey, T S, Nguyen, V Q, Render, Jr, E R

“…The aim of this series of experiments was to determine the dynamic blood flow changes that occur in normal and neoplastic tissues during photodynamic therapy…”
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Chemical modification of normal tissue damage induced by photodynamic therapy by Sigdestad, C P, Fingar, V H, Wieman, T J, Lindberg, R D

“…One of the limitations of successful use of photodynamic therapy (PDT) employing porphyrins is the acute and long-term cutaneous photosensitivity. This paper…”
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Constitutive and stimulated expression of ICAM-1 protein on pulmonary endothelial cells in vivo by FINGAR, V. H, TABER, S. W, COOPER BUSCHEMEYER, W, TEN TIJE, A, CERRITO, P. B, TSENG, M, GUO, H, JOHNSTON, M. N, WIEMAN, T. J

“…The expression of intercellular adhesion molecule-1 (ICAM-1) on pulmonary endothelial cells after stimulus and subsequent binding of neutrophils is a first…”
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Mechanistic studies of PDT-induced vascular damage: evidence that eicosanoids mediate this process by Fingar, V H, Wieman, T J, Doak, K W

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A new model for the study of pulmonary microcirculation: determination of pulmonary edema in rats by Fingar, V H, Taber, S W, Wieman, T J

“…Traditional studies of the lung microcirculation and pulmonary edema commonly employ indirect measurements of vascular hemodynamics or the examination of…”
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Modification of photodynamic therapy-induced hypoxia by fluosol-DA (20%) and carbogen breathing in mice by FINGAR, V. H, MANG, T. S, HENDERSON, B. W

“…The administration of a perfluorochemical emulsion and carbogen (95% O2, 5% CO2) breathing before photodynamic therapy (PDT) was studied to determine how…”
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Effects of photodynamic therapy using mono-L-aspartyl chlorin e6 on vessel constriction, vessel leakage, and tumor response by MCMAHON, K. S, WIEMAN, T. J, MOORE, P. H, FINGAR, V. H

“…The effect of photodynamic therapy using mono-L-aspartyl chlorin e6 (NPe6) on both direct cytotoxicity and vascular damage was examined. Sprague-Dawley rats…”
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Photodynamic therapy by Wieman, T J, Fingar, V H

“…Photodynamic therapy is an experimental method for treating malignant tumors. Injection of a tumor-localizing and photosensitizing agent and its subsequent…”
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Drug and light dose dependence of photodynamic therapy: a study of tumor cell clonogenicity and histologic changes by Fingar, V H, Potter, W R, Henderson, B W

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The effects of aspirin on microvasculature after photodynamic therapy by Taber, S W, Wieman, T J, Fingar, V H

“…The effects of aspirin (acetylsalicylic acid: ASA) on vessel behavior and tumor response were measured during and after photodynamic therapy (PDT). Changes to…”
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Changes in tumor interstitial pressure induced by photodynamic therapy by Fingar, V H, Wieman, T J, Doak, K W

“…This study has examined the changes in tumor interstitial pressure exhibited during and after photodynamic therapy (PDT). The kinetics of these changes are…”
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