Search Results - "Fine, JS"

Chronic Treatment with the γ-Secretase Inhibitor LY-411,575 Inhibits β-Amyloid Peptide Production and Alters Lymphopoiesis and Intestinal Cell Differentiation by Wong, Gwendolyn T., Manfra, Denise, Poulet, Frederique M., Zhang, Qi, Josien, Hubert, Bara, Thomas, Engstrom, Laura, Pinzon-Ortiz, Maria, Fine, Jay S., Lee, Hu-Jung J., Zhang, Lili, Higgins, Guy A., Parker, Eric M.

“…Inhibition of γ-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce the pathogenic β-amyloid (Aβ)…”
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A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo by Lunn, Charles A, Fine, Jay S, Rojas-Triana, Alberto, Jackson, James V, Fan, Xuedong, Kung, Ted T, Gonsiorek, Waldemar, Schwarz, Martin A, Lavey, Brian, Kozlowski, Joseph A, Narula, Satwant K, Lundell, Daniel J, Hipkin, R William, Bober, Loretta A

“…The expression of the cannabinoid peripheral cannabinoid receptor (CB(2)) receptor on peripheral immune cells suggests that compounds specific for CB(2) might…”
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The Toxicity of SCH 351591, a Novel Phosphodiesterase-4 Inhibitor, in Cynomolgus Monkeys by Losco, Patricia E., Evans, Ellen W., Barat, Stephen A., Blackshear, Pamela E., Reyderman, Larisa, Fine, Jay S., Bober, Loretta A., Anthes, John C., Mirro, Elmer J., Cuss, Francis M.

“…SCH351591, a novel phosphodiesterase-4 inhibitor under investigation as a potential therapeutic for asthma and chronic obstructive pulmonary disease (COPD),…”
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Conditional Expression of Murine Flt3 Ligand Leads to Expansion of Multiple Dendritic Cell Subsets in Peripheral Blood and Tissues of Transgenic Mice by Manfra, Denise J, Chen, Shu-Cheng, Jensen, Kristian K, Fine, Jay S, Wiekowski, Maria T, Lira, Sergio A

“…The analysis of the development and function of distinct subsets of murine dendritic cells (DC) has been hampered by the limited number of these cells in vivo…”
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Factors affecting urinary myoglobin stability in vitro by CHEN-LEVY, Zehava, WENER, Mark H, TOIVOLA, Bert, DAUM, Phyllis, REYES, Morayma, FINE, James S

“…Urine myoglobin concentrations are measured clinically to assess rhabdomyolysis and the related risk of renal damage. We studied urine myoglobin concentrations…”
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Pharmacological characterization of the chemokine receptor, hCCR1 in a stable transfectant and differentiated HL‐60 cells: antagonism of hCCR1 activation by MIP‐1β by Chou, Chuan‐Chu, Fine, Jay S, Pugliese‐Sivo, Catherine, Gonsiorek, Waldemar, Davies, Liza, Deno, Gregory, Petro, Mary, Schwarz, Martin, Zavodny, Paul J, Hipkin, R William

“…C‐C chemokine receptor‐1 (CCR1) has been implicated in mediating a variety of inflammatory conditions including multiple sclerosis and organ rejection…”
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Regulation of granulocyte colony-stimulating factor gene expression by interleukin-17 by Cai, Xiao-Yan, Gommoll Jr, Carl P, Justice, Luminita, Narula, Satwant K, Fine, Jay S

“…Interleukin-17 (IL-17) has been previously reported to induce stromal cells to produce a number of hematopoietic and proinflammatory cytokines, including…”
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The role of LFA-1/ICAM-1 interactions during murine T lymphocyte development by Fine, JS, Kruisbeek, AM

“…We have examined the expression and function of the cell adhesion molecules LFA-1 (CD11a/CD18), ICAM-1 (CD54), and ICAM-2 in murine fetal thymic ontogeny and…”
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Evaluation of signal transduction pathways in chemoattractant-induced human monocyte chemotaxis by Fine, J S, Byrnes, H D, Zavodny, P J, Hipkin, R W

“…The intracellular signaling pathways involved in human monocyte chemotaxis toward a variety of chemoattractant molecules were evaluated using selected…”
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Macrophage inflammatory protein-3 beta enhances IL-10 production by activated human peripheral blood monocytes and T cells by Byrnes, H D, Kaminski, H, Mirza, A, Deno, G, Lundell, D, Fine, J S

“…We report that the addition of human macrophage inflammatory protein-3 beta (MIP-3 beta) to cultures of human PBMCs that have been activated with LPS or PHA…”
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Impairment of leukocyte trafficking in a murine pleuritis model by IL-4 and IL-10 by Fine, Jay S, Rojas-Triana, Alberto, Jackson, James V, Engstrom, Laura W, Deno, Gregory S, Lundell, Daniel J, Bober, Loretta A

“…We have characterized leukocyte migration to the pleural cavity in a methylated-BSA (mBSA)-induced model of murine delayed-type hypersensitivity and evaluated…”
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Escalator-related Injuries in Children by Platt, Shari L, Fine, Jeffrey S, Foltin, George L

“…Escalator-related trauma is uncommon but can cause significant injury. This study reviewed escalator-related injuries in children to determine risk factors,…”
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Impairment of prothymocyte activity by 2,3,7,8-tetrachlorodibenzo-p- dioxin by Fine, JS, Silverstone, AE, Gasiewicz, TA

“…Exposure of experimental animals to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) results in severe thymic atrophy and suppression of cell-mediated and humoral…”
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A Two-Year Study of Microscopic Urinalysis Competency Using the Urinalysis-Review Computer Program by Astion, Michael L, Kim, Sara, Nelson, Amanda, Henderson, Paul J, Phillips, Carla, Bien, Claudia, Mandel, Lynn, Orkand, Adam R, Fine, James S

“…The microscopic examination of urine sediment is one of the most commonly performed microscope-based laboratory tests, but despite its widespread use, there…”
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Teaching the microscopic examination of urine sediment to second year medical students using the Urinalysis-Tutor computer program by Phillips, Carla, Henderson, Paul J, Mandel, Lynn, Kim, Sara, Schaad, Doug, Cooper, Mindy, Bien, Claudia, Orkand, Adam, Wener, Mark H, Fine, James S, Astion, Michael L

“…The microscopic examination of urine sediment is a common diagnostic tool taught to medical students, medical technologists, and others. The urine microscopic…”
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Evaluation of chemokine- and phlogistin-mediated leukocyte chemotaxis using an in vivo sponge model by Fine, J S, Jackson, J V, Rojas-Triana, A, Bober, L A

“…We have directly compared the in vivo activity of a number of chemokines and phlogistins using a modified murine in vivo sponge model in which gelatin sponges…”
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A Specific Stimulator of Granulocyte Colony-Stimulating Factor Accelerates Recovery From Cyclophosphamide-Induced Neutropenia in the Mouse by Fine, Jay S., Cai, Xiao-Yan, Justice, Luminita, Gommoll, Carl P., Hamilton, Linda D., Waters, Tracey A., Narula, Satwant K., Bober, Loretta A., Grace, Michael J.

“…We have identified a small molecular weight compound, SCH 14988, which specifically stimulates in vitro granulocyte-colony stimulating factor (G-CSF )…”
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Influence of IL-10 on murine CFU-pre-B formation by Fine, J S, Macosko, H D, Grace, M J, Narula, S K

“…We have examined the ability of interleukin-10 (IL-10) to influence murine B cell development in vitro and in vivo. In vitro treatment of young adult mouse…”
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BibleCard: network-based virtual database for laboratory information by Fine, J S, Ching, A K, Schneider, J B, Pollum, D, Astion, M L

“…The clinical laboratory's use of computers has evolved beyond the single minicomputer stand-alone system. Our laboratory information system is now part of an…”
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D-phenylalanyl-L-prolyl-L-arginine chloromethyl ketone (PPACK): alternative anticoagulant to heparin salts for blood gas and electrolyte specimens by Lyon, M E, Fine, J S, Henderson, P J, Lyon, A W

“…D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone (PPACK), a selective thrombin inhibitor, was evaluated as an alternative anticoagulant to lithium…”
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