Search Results - "Findlow, S C"

Solution Structure and Dynamics of Oxytetracycline Polyketide Synthase Acyl Carrier Protein from Streptomyces rimosus by Findlow, Stuart C, Winsor, Claire, Simpson, Thomas J, Crosby, John, Crump, Matthew P

“…Type II polyketide synthases (PKSs) utilize a dedicated and essential acyl carrier protein (ACP) in the biosynthesis of a specific polyketide product. As part…”
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Evidence for Plasticity and Structural Mimicry at the Immunoglobulin Light Chain-Protein L Interface by Graille, Marc, Harrison, Steven, Crump, Matthew P., Findlow, Stuart C., Housden, Nicholas G., Muller, Bruno H., Battail-Poirot, Nicole, Sibaı̈, Geneviève, Sutton, Brian J., Taussig, Michael J., Jolivet-Reynaud, Colette, Gore, Michael G., Stura, Enrico A.

“…The multidomain bacterial surface protein L (PpL) is a virulence factor expressed by only 10% ofPeptostreptococcus magnus strains, and its expression is…”
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Self-Malonylation Is an Intrinsic Property of a Chemically Synthesized Type II Polyketide Synthase Acyl Carrier Protein by Arthur, Christopher J, Szafranska, Anna, Evans, Simon E, Findlow, Stuart C, Burston, Steven G, Owen, Philip, Clark-Lewis, Ian, Simpson, Thomas J, Crosby, John, Crump, Matthew P

“…During polyketide biosynthesis, malonyl groups are transferred to the acyl carrier protein (ACP) component of the polyketide synthase (PKS), and it has been…”
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A method for identification of inhibitors of the phosphorylation reactions of bacterial response regulator proteins using (31)P nuclear magnetic resonance spectroscopy by Hubbard, J A, MacLachlan, L K, Johnson, P, Findlow, S C, Ladds, J C, Lewis, C J, Carter, P S, Jones, J J, Fosberry, A P

“…Bacterial response regulators are attractive targets for antibacterial drug development, yet random screening against these targets has failed as yet to…”
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Structure of an Allosteric Inhibitor of LFA-1 Bound to the I-Domain Studied by Crystallography, NMR, and Calorimetry by Crump, Matthew P, Ceska, Thomas A, Spyracopoulos, Leo, Henry, Alistair, Archibald, Sarah C, Alexander, Rikki, Taylor, Richard J, Findlow, Stuart C, O'Connell, James, Robinson, Martyn K, Shock, Anthony

“…LFA-1 (lymphocyte function-associated antigen-1) plays a role in intercellular adhesion and lymphocyte trafficking and activation and is an attractive…”
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