Search Results - "Findlay, Steven"

Consumers' Interest In Provider Ratings Grows, And Improved Report Cards And Other Steps Could Accelerate Their Use by Findlay, Steven D

“…Encouraging patients and consumers to use data and other information in choosing health care providers is an important way to enhance patient engagement and…”
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Mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes by Sherill-Rofe, Dana, Rahat, Dolev, Findlay, Steven, Mellul, Anna, Guberman, Irene, Braun, Maya, Bloch, Idit, Lalezari, Alon, Samiei, Arash, Sadreyev, Ruslan, Goldberg, Michal, Orthwein, Alexandre, Zick, Aviad, Tabach, Yuval

“…The homologous recombination repair (HRR) pathway repairs DNA double-strand breaks in an error-free manner. Mutations in HRR genes can result in increased…”
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Provider Perspectives of Patient Experiences in Primary Care Imaging by Zigman Suchsland, Monica L, Hardy, Victoria, Zhang, Ying, Vigil, Patrick D, Collins, Kimberly L, Woodhouse, William M, Chou, Roger, Findlay, Steven D, Lavallee, Danielle C, Thompson, Matthew J

“…Imaging tests are a widely used tool in primary care with many known benefits. Without an understanding of which outcomes matter the most to patients,…”
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Direct-to-consumer promotion of prescription drugs. Economic implications for patients, payers and providers by Findlay, S D

“…Spending on outpatient prescription drugs in the US is accelerating rapidly. Although numerous factors are driving this trend, attention has recently focused…”
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Bringing The DERP To Consumers: 'Consumer Reports Best Buy Drugs' by Findlay, Steven D

“…Consumers Union, publisher of Consumer Reports magazine, has used the drug class reviews of the Drug Effectiveness Review Project (DERP) as one critical…”
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PERSPECTIVE: Bringing The DERP To Consumers: 'Consumer Reports Best Buy Drugs' by Findlay, Steven D

“…Consumers Union, publisher of Consumer Reports magazine, has used the drug class reviews of the Drug Effectiveness Review Project (DERP) as one critical…”
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3157 – GENOME-WIDE CRISPR SCREENING IDENTIFIES THE MITOCHONDRIAL PYRUVATE CARRIER AS A MODULATOR OF BORTEZOMIB IN MULTIPLE MYELOMA by Orthwein, Alexandre, Findlay, Steven

“…Proteasome inhibitors, including the FDA-approved bortezomib (BTZ), are frequently used for the treatment of patients affected by multiple myeloma (MM)…”
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Consumers And Quality-Driven Health Care: A Call To Action by Shaller, Dale, Sofaer, Shoshanna, Findlay, Steven D, Hibbard, Judith H, Lansky, David, Delbanco, Suzanne

“…A key strategy for driving improvements in health care quality is providing comparative quality information to consumers. This strategy will not work, and…”
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An E3 ubiquitin ligase localization screen uncovers DTX2 as a novel ADP-ribosylation-dependent regulator of DNA double-strand break repair by Djerir, Billel, Marois, Isabelle, Dubois, Jean-Christophe, Findlay, Steven, Morin, Théo, Senoussi, Issam, Cappadocia, Laurent, Orthwein, Alexandre, Maréchal, Alexandre

“…DNA double-strand breaks (DSBs) elicit an elaborate response to signal damage and trigger repair via two major pathways: nonhomologous end-joining (NHEJ),…”
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Identification of Novel Therapeutic Vulnerabilities in Multiple Myeloma by Findlay, Steven

“…Multiple myeloma (MM) is one of the most common hematological malignancies in the western world, with an incidence rate that has increased over the last 20…”
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SHLD2/FAM35A co‐operates with REV7 to coordinate DNA double‐strand break repair pathway choice by Findlay, Steven, Heath, John, Luo, Vincent M, Malina, Abba, Morin, Théo, Coulombe, Yan, Djerir, Billel, Li, Zhigang, Samiei, Arash, Simo‐Cheyou, Estelle, Karam, Martin, Bagci, Halil, Rahat, Dolev, Grapton, Damien, Lavoie, Elise G, Dove, Christian, Khaled, Husam, Kuasne, Hellen, Mann, Koren K, Klein, Kathleen Oros, Greenwood, Celia M, Tabach, Yuval, Park, Morag, Côté, Jean‐Francois, Masson, Jean‐Yves, Maréchal, Alexandre, Orthwein, Alexandre

“…DNA double‐strand breaks (DSBs) can be repaired by two major pathways: non‐homologous end‐joining (NHEJ) and homologous recombination (HR). DNA repair pathway…”
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The Neurodevelopmental Protein POGZ Suppresses Metastasis in Triple Negative Breast Cancer by Attenuating TGFβ Signaling by Heath, John, Mirabelli, Caitlynn, Annis, Matthew G, Sabourin, Valerie, Hébert, Steven, Findlay, Steven, Kim, HaEun, Witcher, Michael, Kleinman, Claudia L, Siegel, Peter M, Orthwein, Alexandre, Ursini-Siegel, Josie

“…The pogo transposable element derived zinc finger protein, POGZ, is notably associated with neurodevelopmental disorders through its role in gene…”
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Effects of budesonide by means of the Turbuhaler on the hypothalmic-pituitary-adrenal axis in asthmatic subjects: A dose-response study by Aaronson, Donald, Kaiser, Harold, Dockhorn, Robert, Findlay, Steven, Korenblat, Philip, Thorsson, Lars, Källén, Anders

“…Background: As a general phenomenon, corticosteroids may suppress the activity in the hypothalamic-pituitary-adrenal (HPA) axis. The adrenal stimulation test…”
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The Deubiquitylase Otub1 Regulates the Chemotactic Response of Splenic B Cells by Modulating the Stability of the γ-Subunit Gng2 by Luo, Vincent M, Shen, Connie, Worme, Samantha, Bhagrath, Aanya, Simo-Cheyou, Estelle, Findlay, Steven, Hébert, Steven, Wai Lam Poon, William, Aryanpour, Zahra, Zhang, Thomas, Zahedi, René P, Boulais, Jonathan, Buchwald, Zachary S, Borchers, Christoph H, Côté, Jean-Francois, Kleinman, Claudia L, Mandl, Judith N, Orthwein, Alexandre

“…The ubiquitin proteasome system performs the covalent attachment of lysine 48-linked polyubiquitin chains to substrate proteins, thereby targeting them for…”
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POGZ promotes homology‐directed DNA repair in an HP1‐dependent manner by Heath, John, Cheyou, Estelle Simo, Findlay, Steven, Luo, Vincent M, Carpio, Edgar Pinedo, Lee, Jeesan, Djerir, Billel, Chen, Xiaoru, Morin, Théo, Lebeau, Benjamin, Karam, Martin, Bagci, Halil, Grapton, Damien, Ursini‐Siegel, Josie, Côté, Jean‐Francois, Witcher, Michael, Richard, Stéphane, Maréchal, Alexandre, Orthwein, Alexandre

“…The heterochromatin protein HP1 plays a central role in the maintenance of genome stability but little is known about how HP1 is controlled. Here, we show that…”
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Effect of fluticasone propionate aqueous nasal spray versus oral prednisone on the hypothalamic-pituitary-adrenal axis by Vargas, Ramón, Dockhorn, Robert J., Findlay, Steven R., Korenblat, Phillip E., Field, Elizabeth A., Kral, Kenneth M.

“…Background: Fluticasone propionate is a glucocorticoid with negligible oral bioavailability and very low intranasal bioavailability that is used as an…”
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The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma by Findlay, Steven, Nair, Remya, Merrill, Ronald A., Kaiser, Zafir, Cajelot, Alexandre, Aryanpour, Zahra, Heath, John, St-Louis, Catherine, Papadopoli, David, Topisirovic, Ivan, St-Pierre, Julie, Sebag, Michael, Kesarwala, Aparna H., Hulea, Laura, Taylor, Eric B., Shanmugam, Mala, Orthwein, Alexandre

“…•Mitochondrial pyruvate import plays a critical role in regulating bioenergetic and proteolytic capacities of MM cells. [Display omitted] Multiple myeloma (MM)…”
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Fluticasone propionate aqueous nasal spray is safe and effective for children with seasonal allergic rhinitis by GROSSMAN, J, BANOV, C, FIELD, E. A, ROGENES, P. R, BRONSKY, R. A, NATHAN, R. A, PEARLMAN, D, WINDER, J. A, RATNER, P. H, MENDELSON, L, FINDLAY, S. R, KRAL, K. M

“…Fluticasone propionate aqueous nasal spray, a new topical corticosteroid preparation, is effective when given as 200 micrograms once daily in patients (> 12…”
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SHLD 2/ FAM 35A co‐operates with REV 7 to coordinate DNA double‐strand break repair pathway choice by Findlay, Steven, Heath, John, Luo, Vincent M, Malina, Abba, Morin, Théo, Coulombe, Yan, Djerir, Billel, Li, Zhigang, Samiei, Arash, Simo‐Cheyou, Estelle, Karam, Martin, Bagci, Halil, Rahat, Dolev, Grapton, Damien, Lavoie, Elise G, Dove, Christian, Khaled, Husam, Kuasne, Hellen, Mann, Koren K, Klein, Kathleen Oros, Greenwood, Celia M, Tabach, Yuval, Park, Morag, Côté, Jean‐Francois, Masson, Jean‐Yves, Maréchal, Alexandre, Orthwein, Alexandre

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Managed behavioral health care in 1999: an industry at a crossroads by Findlay, S

“…From a few fledgling initiatives in the early 1980s in California, managed care has grown to a $4.4 billion industry, covering 176.8 million people in the US…”
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