Search Results - "Findlay, M P"

A randomized phase II study comparing capecitabine alone with capecitabine and oral cyclophosphamide in patients with advanced breast cancer-cyclox II by Harvey, V.J., Sharples, K.J., Isaacs, R.J., Jameson, M.B., Jeffery, G.M., McLaren, B.R., Pollard, S., Riley, G.A., Simpson, A.B., Hinder, V.A., Scott, J.N., Dzhelali, M.V., Findlay, M.P.

“…Capecitabine and cyclophosphamide are active in patients with advanced breast cancer, have non-overlapping toxic effects and synergy pre-clinically. We…”
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Chemotherapy-induced reversible posterior leucoencephalopathy syndrome by Han, C. H., Findlay, M. P.

“…Reversible posterior leucoencephalopathy syndrome is a neurological condition seen in various areas of acute medicine, including the administration of…”
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Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy by FINDLAY, M. P. N, CUNNINGHAM, D, MORGAN, G, CLINTON, S, HARDCASTLE, A, AHERNE, G. W

“…The increasing interest in 5-fluorouracil (5-FU) modulation and the development of new antifolates has focused attention in recent studies on the expression of…”
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The Cost of Admiralty: The development and condition of Britain's modern naval shipbuilding programme, 1832-2015 by Findlay, M P

“…Reform of government institutions is no new affair; indeed, government reform is like a chameleon that changes colours. Today's colour is military procurement…”
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High CYP2C19 phenotypic variability in gastrointestinal cancer patients by Burns, K. E., Lo, W.-Y., Findlay, M. P., Sharples, K., Laking, G., Helsby, N. A.

“…Purpose CYP2C19 contributes to the metabolism of several chemotherapeutic agents. The CYP2C19 homozygous null function genotype strongly predicts activity…”
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Measurement of plasma 5-fluorouracil by high-performance liquid chromatography with comparison of results to tissue drug levels observed using in vivo 19F magnetic resonance spectroscopy in patients on a protracted venous infusion with or without interferon-α by Findlay, M. P. N., Raynaud, F., Cunningham, D., Iveson, A., Collins, D. J., Leach, M. O.

“…Purpose To measure plasma 5-fluorouracil (5-FU) levels using high-performance liquid chromatography (HPLC) and compare the findings to the tissue metabolism of…”
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The non-invasive monitoring of low dose, infusional 5-fluorouracil and its modulation by interferon-alpha using in vivo 19F magnetic resonance spectroscopy in patients with colorectal cancer: a pilot study by Findlay, M P, Leach, M O, Cunningham, D, Collins, D J, Payne, G S, Glaholm, J, Mansi, J L, McCready, V R

“…5-Fluorouracil (5-FU) is the most widely used cytotoxic drug in oncology and the only one useful in the management of colorectal cancer - a leading cause of…”
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Active surveillance after orchiectomy for nonseminomatous testicular germ cell tumors: Late relapse may occur by Boyer, Michael J., Cox, Keith, Tattersall, Martin H.N., Findlay, Michael P.N., Grygiel, John, Rogers, John

“…To review the outcome of men with Stage I nonseminomatous germ cell tumors managed with a policy of active surveillance following orchiectomy. The clinical…”
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Retrospective review of chemotherapy for small cell lung cancer in the elderly: does the end justify the means? by Findlay, M P, Griffin, A M, Raghavan, D, McDonald, K E, Coates, A S, Duval, P J, Gianoutsos, P

“…Between 1978 and 1983, 72 patients aged 70 years or older (median 72, range 70-80) were treated for biopsy-proven, small cell lung cancer (SCLC). Intercurrent…”
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E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer by Guilford, Parry J., Hopkins, Justin B.W., Grady, William M., Markowitz, Sanford D., Willis, Joseph, Lynch, Henry, Rajput, Ashwani, Wiesner, Georgia L., Lindor, Noralane M., Burgart, Lawrence J., Toro, Tumi T., Lee, Don, Limacher, Jean-Marc, Shaw, David W., Findlay, Michael P.N., Reeve, Anthony E.

“…To extend earlier observations of germline E‐cadherin mutations in kindreds with an inherited susceptibility to diffuse gastric cancer, we searched for…”
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Baseline Quality of Life is a Strong and Independent Prognostic Factor for Overall Survival in Metastatic Colorectal Cancer by McGarrah, Patrick, Hubbard, Joleen, Novotny, Paul J., Branda, Megan E., Sargent, Daniel S., Morton, Roscoe F., Fuchs, Charles S., Benson, Al B., Williamson, Stephen K., Findlay, Brian P., Alberts, Steven R., Goldberg, Richard M., Sloan, Jeff A.

“…Background Previous studies have established that higher baseline quality of life (QOL) scores are associated with improved survival in patients with…”
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A randomized phase II study comparing capecitabine (C) with C plus oral cyclophosphamide (CCy) in patients (pts) with advanced breast cancer (BC) by Harvey, V. J., Sharples, K., Isaacs, R., Jameson, M. B., Jeffery, M., McLaren, B., Pollard, S., Riley, G., Simpson, A., Findlay, M. P.

“…Abstract only…”
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The case for a student honor code and beyond by Davis, Mardell, Johnston, Sarah R., DiMicco, Wendy, Findlay, Margaret P., Taylor, Judy A.

“…Preparing graduates to enter practice as responsible and accountable nurses is an essential goal of nursing programs. Faculty must be deliberate in their…”
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A randomized phase II study comparing capecitabine alone with capecitabine and oral cyclophosphamide in patients with advanced breast cancer-cyclox II by Harvey, V J, Sharples, K J, Isaacs, R J, Jameson, M B, Jeffery, G M, McLaren, B R, Pollard, S, Riley, G A, Simpson, A B, Hinder, V A, Scott, J N, Dzhelali, M V, Findlay, M P

“…Capecitabine and cyclophosphamide are active in patients with advanced breast cancer, have non-overlapping toxic effects and synergy pre-clinically. We…”
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Dose-intense capecitabine, oxaliplatin and bevacizumab as first line treatment for metastatic, unresectable colorectal cancer: a multi-centre phase II study by Jackson, Christopher G C A, Sharples, Katrina, Thompson, Paul I, O'Donnell, Anne, Robinson, Bridget Anne, Perez, David J, Adams, Jacqui, Isaacs, Richard, Deva, Sanjeev, Hinder, Victoria A, Findlay, Michael P

“…Dose intense chemotherapy may improve efficacy with acceptable toxicity. A phase II study was conducted to determine the feasibility of a dose-intense two…”
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In vivo monitoring of fluoropyrimidine metabolites: magnetic resonance spectroscopy in the evaluation of 5-fluorouracil by Findlay, M P, Leach, M O

“…Since 5-fluorouracil (5-FU) was synthesized in the late 1950s it has become an important component of many anticancer treatment regimens. The increasing volume…”
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Rocuronium pretreatment reduces suxamethonium-induced myalgia: comparison with vecuronium by Findlay, G P, Spittal, M J

“…We have studied, in 150 patients undergoing elective oral surgery, the effectiveness and sequelae of pretreatment with rocuronium for reducing myalgia after…”
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