Search Results - "Findlay, J. B. C"

Design, synthesis, and biological evaluation of aryl piperazines with potential as antidiabetic agents via the stimulation of glucose uptake and inhibition of NADH:ubiquinone oxidoreductase by Devine, R., Kelada, M., Leonard, S., Martin, D.S.D., Walsh, J.M.D., Breen, C.J., Driver, R.B., Kinsella, G.K., Findlay, J.B.C., Stephens, J.C.

“…The management of blood glucose levels and the avoidance of diabetic hyperglycemia are common objectives of many therapies in the treatment of diabetes. An…”
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Effects of ACh and adenosine mediated by Kir3.1 and Kir3.4 on ferret ventricular cells by Dobrzynski, H, Janvier, N C, Leach, R, Findlay, J B C, Boyett, M R

“…The inotropic effects of ACh and adenosine on ferret ventricular cells were investigated with the action potential-clamp technique. Under current clamp, both…”
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PROMISE: a database of bioinorganic motifs by Degtyarenko, K. N., North, A. C. T., Findlay, J. B. C.

“…The promise (prosthetic centres and metal ions in protein active sites) database aims to present comprehensive sequence, structural, functional and…”
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Biochemical characteristics of guanine nucleotide binding protein alpha-subunit recombinant protein and three mutants: investigation of a domain motion involved in GDP-GTP exchange by Mello, L V, Millner, P A, Findlay, J B C

“…Our previous studies using molecular dynamics have shown a hinge bending motion between the helical and the GTPase domains of GalphaT (Mello et al., 1998). The…”
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Molecular cloning and primary structure of squid (Loligo forbesi) rhodopsin, a phospholipase C-directed G-protein-linked receptor by HALL, M. D, HOON, M. A, RYGA, N. J. P, POTTINGER, J. D. D, KEEN, J. N, SAIBIL, H. R, FINDLAY, J. B. C

“…The sequence of squid (Loligo forbesi) rhodopsin was determined by protein and cDNA sequencing. The protein has close similarity to octopus rhodopsin, having…”
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The retinol-binding protein system: a potential paradigm for steroid-binding globulins? by Redondo, C, Burke, B J, Findlay, J B C

“…Retinol (vitamin A) is an example of a small molecule that is essential for higher organisms; its utilisation has been involved in the evolution of a number of…”
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The identification and purification of the heterotrimeric GTP-binding protein from squid (Loligo forbesi) photoreceptors by POTTINGER, J. D. D, RYBA, N. J. P, KEEN, J. N, FINDLAY, J. B. C

“…The principal GTP-binding protein (G-protein) from squid (Loligo forbesi) photoreceptor membranes has been identified by amino acid sequencing. The…”
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Fingerprinting G-protein-coupled receptors by Attwood, T K, Findlay, J B

“…Recently we reported the design of a discriminating fingerprint for rhodopsin-like G-protein-coupled receptors (GPCRs). The fingerprint encodes the seven…”
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Primary Structure of a β Subunit of α-Dendrotoxin-Sensitive K+Channels from Bovine Brain by Scott, V. E. S., Rettig, J., Parcej, D. N., Keen, J. N., Findlay, J. B. C., Pongs, O., Dolly, J. O.

“…Voltage-dependent cation channels are large heterooligomeric proteins. Heterologous expression of cDNAs encoding the α subunits alone of K+, Na+, or…”
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The structure of β -lactoglobulin and its similarity to plasma retinol-binding protein by Papiz, M. Z, Sawyer, L, Eliopoulos, E. E, North, A. C. T, Findlay, J. B. C, Sivaprasadarao, R, Jones, T. A, Newcomer, M. E, Kraulis, P. J

“…Since its first isolation, bovine beta-lactoglobulin (BLG) has been an enigma: although it is abundant in the whey fraction of milk, its function is still not…”
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Solubilization and purification of the retinol-binding protein receptor from human placental membranes by SIVAPRASADARAO, A, MOHAMMED BOUDJELAL, FINDLAY, J. B. C

“…The membrane receptor for retinol-binding protein (RBP) has been solubilized from human placental brush-border membranes with octyl-beta-glucoside, Nonidet…”
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The relationship between the agonist‐induced activation and desensitization of the human tachykinin NK2 receptor expressed in Xenopus oocytes by Maudsley, S, Gent, J P, Findlay, J B C, Donnelly, D

“…Repeated applications of neurokinin A (NKA) to oocytes injected with 25 ng wild‐type hNK2 receptor cRNA caused complete attenuation of second and subsequent…”
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Evidence that the 16 kDa proteolipid (subunit c) of the vacuolar H+-ATPase and ductin from gap junctions are the same polypeptide in Drosophila and Manduca: molecular cloning of the Vha16k gene from Drosophila by Finbow, M.E, Goodwin, S.F, Meagher, L, Lane, N.J, Keen, J, Findlay, J.B.C, Kaiser, K

“…The 16 kDa proteolipid (subunit c) of the eukaryotic vacuolar H(+)-ATPase (V-ATPase) is closely related to the ductin polypeptide that forms the connexon…”
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The molecular cloning of the squid (Loligo forbesi) visual Gq-α subunit and its expression in Saccharomyces cerevisiae by RYBA, N. J. P, FINDLAY, J. B. C, REID, J. D

“…The sequence of the alpha-subunit of the major G-protein from the squid (Loligo forbesi) retina was predicted from its cDNA to be a member of the Gq subclass…”
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Expression of functional human retinol-binding protein in Escherichia coli using a secretion vector by ASIPU SIVAPRASADARAO, FINDLAY, J. B. C

“…In order to express human serum retinol-binding protein (sRBP) in Escherichia coli in a form that is structurally indistinguishable from the native protein, we…”
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Modulation by protein kinase A of a cloned rat brain potassium channel expressed in Xenopus oocytes by WILSON, G. G, O'NEILL, C. A, SIVAPRASADARAO, A, FINDLAY, J. B. C, WRAY, D

“…A potassium channel from rat brain was expressed in Xenopus oocytes in order to study modulation of channel function by phosphorylation via protein kinase A…”
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Autosomal dominant retinitis pigmentosa: a novel mutation in the rhodopsin gene in the original 3q linked family by Farrar, G J, Findlay, J B, Kumar-Singh, R, Kenna, P, Humphries, M M, Sharpe, E, Humphries, P

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Sequence of the β-subunit of the phosphatidylinositol-specific phospholipase C-directed GTP-binding protein from squid (Loligo forbesi) photoreceptors by RYBA, N. J. P, POTTINGER, J. D. D, KEEN, J. N, FINDLAY, J. B. C

“…The beta-subunit (G-beta) of the squid (Loligo forbesi) visual GTP-binding protein (G-protein), thought to be associated with a phosphatidylinositol-specific…”
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Lipocalin based biosensors for low mass hydrophobic analytes; development of a novel SAM for polyhistidine tagged proteins by Rodgers, M.A., Findlay, J.B.C., Millner, P.A.

“…Lipocalins, which are compact binding proteins for odorants, have potential as bioreceptors for small hydrophobic analytes. Studies on several isoforms of the…”
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The lobster carapace carotenoprotein, α-crustacyanin : a possible role for tryptophan in the bathochromic spectral shift of protein-bound astaxanthin by ZAGALSKY, P. F, ELIOPOULOS, E. E, FINDLAY, J. B. C

“…Crustacyanin, cross-linked with dimethyl pimelimidate to stabilize the protein against denaturation, was used to test the effects of tryptophan modification…”
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