Search Results - "Finch, J. T"

Amyloid Fibers are Water-Filled Nanotubes by Perutz, M. F., Finch, J. T., Berriman, J., Lesk, A.

“…A study of papers on amyloid fibers suggested to us that cylindrical β-sheets are the only structures consistent with some of the x-ray and electron microscope…”
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Two's company, three's a crowd: co-occurring pollinators and parasite species in Breynia oblongifolia (Phyllanthaceae) by Finch, J T D, Power, S A, Welbergen, J A, Cook, J M

“…Obligate pollination mutualisms (OPMs) are specialized interactions in which female pollinators transport pollen between the male and female flowers of a…”
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Crystal structure of globular domain of histone H5 and its implications for nucleosome binding by Ramakrishnan, V, Finch, J. T, Graziano, V, Lee, P. L, Sweet, R. M

“…The structure of GH5, the globular domain of the linker histone H5, has been solved to 2.5 A resolution by multiwavelength anomalous diffraction on crystals of…”
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Assembly and Analysis of Conical Models for the HIV-1 Core by Ganser, Barbie K., Li, Su, Klishko, Victor Y., Finch, John T., Sundquist, Wesley I.

“…The genome of the human immunodeficiency virus (HIV) is packaged within an unusual conical core particle located at the center of the infectious virion. The…”
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Glutamine Repeats as Polar Zippers: Their Possible Role in Inherited Neurodegenerative Diseases by Perutz, Max F., Johnson, Tony, Suzuki, Masashi, Finch, John T.

“…Four inherited neurodegenerative diseases are linked to abnormally expanded repeats of glutamine residues in the affected proteins. Molecular modeling followed…”
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The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements by Schwabe, J W, Chapman, L, Finch, J T, Rhodes, D

“…The nuclear hormone receptors are a superfamily of ligand-activated DNA-binding transcription factors. We have determined the crystal structure (at 2.4 A) of…”
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Crystal structure of uncleaved ovalbumin at 1.95 A resolution by Stein, P E, Leslie, A G, Finch, J T, Carrell, R W

“…Ovalbumin, the major protein in avian egg-white, is a non-inhibitory member of the serine protease inhibitor (serpin) superfamily. The crystal structure of…”
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Human Immunodeficiency Virus Type 1 Regulator of Virion Expression, Rev, Forms Nucleoprotein Filaments After Binding to a Purine-Rich "bubble" Located within the Rev-Responsive Region of Viral mRNAs by Heaphy, Shaun, Finch, John T., Gait, Michael J., Karn, Jonathan, Singh, Mohinder

“…The human immunodeficiency virus type 1 rev protein binds with high affinity (K$_d < 1-3$nM) to a purine-rich "bubble" containing bulged GG and GUA residues on…”
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Structure of the nucleosome core particle at 7 resolution by Richmond, T. J, Finch, J. T, Rushton, B, Rhodes, D, Klug, A

“…The crystal structure of the nucleosome core particle has been solved to 7 A resolution. The right-handed B-DNA superhelix on the outside contains several…”
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The structure of an oligo(dA)·oligo(dT) tract and its biological implications by Nelson, Hillary C. M, Finch, John T, Luisi, Bonaventura F, Klug, Aaron

“…Poly(dA).poly(dT) has unusual properties in that it cannot associate into nucleosomes and short, phased runs of it cause DNA bending. The crystal structure of…”
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Binding of the dye congo red to the amyloid protein pig insulin reveals a novel homology amongst amyloid-forming peptide sequences by Turnell, W G, Finch, J T

“…The three-dimensional structure has been determined of a complex of the dye Congo Red, a specific stain for amyloid deposits, bound to the amyloid protein…”
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Crystal structure of ovalbumin as a model for the reactive centre of serpins by Stein, Penelope E, Leslie, Andrew G. W, Finch, John T, Turnell, William G, McLaughlin, Paul J, Carrell, Robin W

“…The serpins are a widely distributed family of proteins with diverse functions; they include the key serine protease inhibitors of human plasma as well as…”
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A spacer protein in the Saccharomyces cerevisiae spindle pole body whose transcript is cell cycle-regulated by Kilmartin, John V., Dyos, Susan L., Kershaw, Douglas, Finch, John T.

“…Monoclonal antibodies against the 110-kD component of the yeast spindle pole body (SPB) were used to clone the corresponding gene SPC110. SPC110 is identical…”
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The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage by Scott, W G, Finch, J T, Klug, A

“…We have solved the crystal structure of an all-RNA hammerhead ribozyme having a single 2'-O-methyl cytosine incorporated at the active site to prevent…”
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Analysis of Co-Crystal Structures to Identify the Stereochemical Determinants of the Orientation of TBP on the TATA Box by Suzuki, Masashi, Allen, Mark D., Yagi, Naoto, Finch, John T.

“…Possible stereochemical determinants of the orientation of TBP on the TATA box are discussed using the crystal coordinates of TBP-TATA complexes, which have…”
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Solenoidal Model for Superstructure in Chromatin by Finch, J. T., Klug, A.

“…Chromatin prepared by brief digestion of nuclei with micrococcal nuclease, and extracted in 0.2 mM EDTA, appears in the electron microscope as filaments of…”
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Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA by Laskey, R. A, Honda, B. M, Mills, A. D, Finch, J. T

“…The nucleosome subunits of chromatin are assembled from histones and DNA by an acidic protein which binds histones. The nucleosome assembly protein has been…”
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The mechanism of Z α1-antitrypsin accumulation in the liver by LOMAS, D. A, EVANS, D. L, FINCH, J. T, CARRELL, R. W

“…MOST northern Europeans have only the normal M form of the plasma protease inhibitor α1,-antitrypsin, but some 4% are heterozygotes for the Z deficiency…”
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Cooperative binding of the globular domains of histones H1 and H5 to DNA by Thomas, Jean O., Rees, Christine, Finch, John T.

“…In view of the likely role of H1-H1 interactions in the stabilization of chromatin higher order structure, we have asked whether interactions can occur between…”
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A low resolution structure for the histone core of the nucleosome by Klug, A, Rhodes, D, Smith, J, Finch, J. T, Thomas, J. O

“…Image reconstruction to 22 A resolution of the histone octamer (H3)2(H4)2(H2A)2(H2B)2 shows it to have a 2-fold axis of symmetry, and the overall shape of the…”
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