Search Results - "Finch, Emily R."
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Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone treated mice
Published in Haematologica (Roma) (01-08-2021)“…Recent clinical trials in children with acute lymphoblastic leukemia (ALL) indicate that severe hypertriglyceridemia (> 1000 mg/dL) during therapy is…”
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2
Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells
Published in Cell reports (Cambridge) (25-07-2023)“…Relapse of acute myeloid leukemia (AML) remains a significant concern due to persistent leukemia-initiating stem cells (LICs) that are typically not targeted…”
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3
Comprehensive analysis of dose intensity of acute lymphoblastic leukemia chemotherapy
Published in Haematologica (Roma) (01-02-2022)“…Chemotherapy dosages are often compromised, but most reports lack data on dosages that are actually delivered. In two consecutive acute lymphoblastic leukemia…”
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4
Distinct DNA methylation signatures associated with blood lipids as exposures or outcomes among survivors of childhood cancer: a report from the St. Jude lifetime cohort
Published in Clinical epigenetics (28-02-2023)“…DNA methylation (DNAm) plays an important role in lipid metabolism, however, no epigenome-wide association study (EWAS) of lipid levels has been conducted…”
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5
Physical activity and fitness in childhood cancer survivors: A scoping review
Published in Aging and cancer (01-12-2021)“…Background Estimates indicate that nearly 8% of the over 500,000 survivors of childhood cancer living in the United States are frail in their fourth and fifth…”
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Energy cost of walking in obese survivors of acute lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort
Published in Frontiers in pediatrics (28-10-2022)“…Adult survivors of childhood acute lymphoblastic leukemia (ALL) have impaired adaptive physical function and poor health-related quality of life (HRQoL)…”
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7
Activation of PPARγ by endogenous prostaglandin J2 mediates the antileukemic effect of selenium in murine leukemia
Published in Blood (30-03-2017)“…Supplementation with nontoxic doses of micronutrient selenium has been shown to alleviate chronic myelogenous leukemia (CML) via the elimination of leukemia…”
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Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia
Published in Pediatric blood & cancer (01-01-2020)“…Background Glucocorticoids and asparaginase, used to treat acute lymphoblastic leukemia (ALL), can cause hypertriglyceridemia. We compared triglyceride levels,…”
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Association between CEP72 genotype and persistent neuropathy in survivors of childhood acute lymphoblastic leukemia
Published in Leukemia (01-04-2022)Get full text
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10
Effects of zoledronic acid on osteonecrosis and acute lymphoblastic leukemia treatment efficacy in preclinical models
Published in Pediatric blood & cancer (01-10-2021)“…Background Osteonecrosis is a devastating side effect of acute lymphoblastic leukemia (ALL) therapy. Associations between bone density loss and osteonecrosis…”
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11
Dasatinib does not exacerbate dexamethasone‐induced osteonecrosis in murine models of acute lymphoblastic leukemia therapy
Published in Pediatric blood & cancer (01-04-2022)“…Introduction There are clinical reports that the incorporation of dasatinib may increase the frequency of osteonecrosis in acute lymphoblastic leukemia (ALL)…”
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12
Bloodstream infections exacerbate incidence and severity of symptomatic glucocorticoid‐induced osteonecrosis
Published in Pediatric blood & cancer (01-06-2019)“…Background Osteonecrosis is a common toxicity associated with glucocorticoid (e.g., dexamethasone and prednisone) treatment of children with acute…”
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13
Selenium Suppresses Leukemia through the Action of Endogenous Eicosanoids
Published in Cancer research (Chicago, Ill.) (15-07-2014)“…Eradicating cancer stem-like cells (CSC) may be essential to fully eradicate cancer. Metabolic changes in CSC could hold a key to their targeting. Here, we…”
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14
Race and Ethnicity, Socioeconomic Factors, and Epigenetic Age Acceleration in Survivors of Childhood Cancer
Published in JAMA network open (01-07-2024)“…Current research in epigenetic age acceleration (EAA) is limited to non-Hispanic White individuals. It is imperative to improve inclusivity by considering…”
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Epigenetic Age in Peripheral Blood Among Children, Adolescent, and Adult Survivors of Childhood Cancer
Published in JAMA network open (03-04-2023)“…Certain cancer therapies are risk factors for epigenetic age acceleration (EAA) among survivors of childhood cancer, and EAA is associated with chronic health…”
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Chemopreventive Effects of Dietary Eicosapentaenoic Acid Supplementation in Experimental Myeloid Leukemia
Published in Cancer prevention research (Philadelphia, Pa.) (01-10-2015)“…Current therapies for treatment of myeloid leukemia do not eliminate leukemia stem cells (LSC), leading to disease relapse. In this study, we supplemented mice…”
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Physical performance limitations and participation restrictions among cancer survivors: A population-based study from NHANES data 2015-2018
Published in Journal of clinical oncology (01-06-2022)“…12096 Background: Anti-cancer therapies have improved survival outcomes in cancer survivors; however, therapy-related toxicities may impact organ structure and…”
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Associations between diet quality and chronic health conditions (CHCs) in adult survivors of childhood cancer in the St. Jude Lifetime Cohort Study (SJLIFE)
Published in Journal of clinical oncology (01-06-2022)“…12095 Background: Survivors of childhood cancer are at increased risk for early development of CHCs, including metabolic syndrome (MetS), low bone mineral…”
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Protein, fat, and animal food intakes and premature aging in adult survivors of childhood cancer: St. Jude Lifetime (SJLIFE) cohort
Published in Journal of clinical oncology (01-06-2022)“…10055 Background: Childhood cancer survivors are a growing population who appear to be at higher risk for premature aging and age-related chronic health…”
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20
The Effect of Asparaginase on Serum Triglycerides during Therapy for Acute Lymphoblastic Leukemia
Published in Blood (29-11-2018)“…Introduction: Treatment for acute lymphoblastic leukemia (ALL) with asparaginase (ASP) and glucocorticoids, such as dexamethasone (DEX), can cause changes in…”
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