Search Results - "Finch, AR"

Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization by Caunt, Christopher J, Finch, Ann R, Sedgley, Kathleen R, Oakley, Lisa, Luttrell, Louis M, McArdle, Craig A

“…Activation of seven-transmembrane region receptors typically causes their phosphorylation with consequent arrestin binding and desensitization. Arrestins also…”
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Trafficking and signalling of gonadotrophin‐releasing hormone receptors: an automated imaging approach by Finch, AR, Sedgley, KR, Armstrong, SP, Caunt, CJ, McArdle, CA

“…Gonadotrophin‐releasing hormone (GnRH) is a neuropeptide that mediates central control of reproduction by stimulating gonadotrophin secretion from the…”
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Signaling and Antiproliferative Effects of Type I and II Gonadotropin-Releasing Hormone Receptors in Breast Cancer Cells by Finch, Ann R., Green, Lisa, Hislop, James N., Kelly, Eamonn, McArdle, Craig A.

“…GnRH receptors (GnRH-Rs) mediate direct antiproliferative effects on hormone-dependent cancer cells. GnRH-Rs can be grouped according to ligand specificity…”
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Regulation of Gonadotropin-Releasing Hormone Receptors by Protein Kinase C: Inside Out Signalling and Evidence for Multiple Active Conformations by Caunt, Christopher J, Hislop, James N, Kelly, Eamonn, Matharu, Anne-Lise, Green, Lisa D, Sedgley, Kathleen R, Finch, Ann R, McArdle, Craig A

“…Desensitization and internalization of G protein-coupled receptors can be mediated by phosphorylation within the C-terminal tail, facilitating β-arrestin…”
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