Search Results - "Finan, Kieran"

depletion attraction: an underappreciated force driving cellular organization by Marenduzzo, Davide, Finan, Kieran, Cook, Peter R

“…Cellular structures are shaped by hydrogen and ionic bonds, plus van der Waals and hydrophobic forces. In cells crowded with macromolecules, a little-known and…”
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Multiscale Spatial Organization of RNA Polymerase in Escherichia coli by Endesfelder, Ulrike, Finan, Kieran, Holden, Seamus J., Cook, Peter R., Kapanidis, Achillefs N., Heilemann, Mike

“…Nucleic acid synthesis is spatially organized in many organisms. In bacteria, however, the spatial distribution of transcription remains obscure, owing largely…”
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T7 RNA polymerase functions in vitro without clustering by Finan, Kieran, Torella, Joseph P, Kapanidis, Achillefs N, Cook, Peter R

“…Many nucleic acid polymerases function in clusters known as factories. We investigate whether the RNA polymerase (RNAP) of phage T7 also clusters when active…”
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A Set of Homo-Oligomeric Standards Allows Accurate Protein Counting by Finan, Kieran, Raulf, Anika, Heilemann, Mike

“…Techniques based on fluorescence microscopy are increasingly used to count proteins in cells, but few stoichiometrically well‐defined standards are available…”
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Super-resolution fluorescence imaging of chromosomal DNA by Zessin, Patrick J.M., Finan, Kieran, Heilemann, Mike

“…Super-resolution microscopy is a powerful tool for understanding cellular function. However one of the most important biomolecules – DNA – remains somewhat…”
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Resolving bundled microtubules using anti-tubulin nanobodies by Mikhaylova, Marina, Cloin, Bas M. C., Finan, Kieran, van den Berg, Robert, Teeuw, Jalmar, Kijanka, Marta M., Sokolowski, Mikolaj, Katrukha, Eugene A., Maidorn, Manuel, Opazo, Felipe, Moutel, Sandrine, Vantard, Marylin, Perez, Frank, van Bergen en Henegouwen, Paul M. P., Hoogenraad, Casper C., Ewers, Helge, Kapitein, Lukas C

“…Microtubules are hollow biopolymers of 25-nm diameter and are key constituents of the cytoskeleton. In neurons, microtubules are organized differently between…”
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Non-specific (entropic) forces as major determinants of the structure of mammalian chromosomes by Finan, Kieran, Cook, Peter R, Marenduzzo, Davide

“…Four specific forces (H-bonds, van der Waals forces, hydrophobic and charge interactions) shape the structure of proteins, and many biologists assume they will…”
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Super-Resolution Fluorescence Microscopy of Transcription Sites in E. coli by Endesfelder, Ulrike, Finan, Kieran, Holden, Seamus, Cook, Peter R., Kapanidis, Achillefs N., Heilemann, Mike

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A Set of Homo-Oligomeric Standards Allows Accurate Protein Counting by Finan, Kieran, Raulf, Anika, Heilemann, Mike

“…Techniques based on fluorescence microscopy are increasingly used to count proteins in cells, but few stoichiometrically well‐defined standards are available…”
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Photoswitchable fluorophores for single-molecule localization microscopy by Finan, Kieran, Flottmann, Benjamin, Heilemann, Mike

“…Over the past decade, fluorescence microscopy has been revolutionized by the development of novel techniques that allow near-molecular resolution. Many such…”
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Super-Resolution Fluorescence Microscopy of Transcription Sites in E. Coli by Finan, Kieran R., Heilemann, Mike, Endesfelder, Ulrike, Holden, Seamus, Cook, Peter R., Kapanidis, Achilles

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Quantitative Studies of Transcription in E.coli With Subdiffraction Fluorescence Microscopy by Endesfelder, Ulrike, Finan, Kieran, Cook, Peter, Kapanidis, Achillefs, Heilemann, Mike

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