Search Results - "Fina, Marie E"

Arginyltransferase (Ate1) regulates the RGS7 protein level and the sensitivity of light-evoked ON-bipolar responses by Fina, Marie E., Wang, Junling, Nikonov, Sergei S., Sterling, Stephanie, Vardi, Noga, Kashina, Anna, Dong, Dawei W.

“…Regulator of G-protein signaling 7 (RGS7) is predominately present in the nervous system and is essential for neuronal signaling involving G-proteins. Prior…”
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mGluR6 deletion renders the TRPM1 channel in retina inactive by Xu, Ying, Dhingra, Anuradha, Fina, Marie E, Koike, Chieko, Furukawa, Takahisa, Vardi, Noga

“…In darkness, glutamate released from photoreceptors activates the metabotropic glutamate receptor 6 (mGluR6) on retinal ON bipolar cells. This activates the G…”
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Autoantibodies in melanoma-associated retinopathy target TRPM1 cation channels of retinal ON bipolar cells by Dhingra, Anuradha, Fina, Marie E, Neinstein, Adam, Ramsey, David J, Xu, Ying, Fishman, Gerald A, Alexander, Kenneth R, Qian, Haohua, Peachey, Neal S, Gregg, Ronald G, Vardi, Noga

“…Melanoma-associated retinopathy (MAR) is characterized by night blindness, photopsias, and a selective reduction of the electroretinogram b-wave. In certain…”
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Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements by Tummala, Shanti R, Neinstein, Adam, Fina, Marie E, Dhingra, Anuradha, Vardi, Noga

“…L-type voltage gated calcium channels in retina localize primarily at the presynaptic active zones of photoreceptors and bipolar cells where they modulate…”
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Arginylation Regulates G-protein Signaling in the Retina by Fina, Marie E, Wang, Junling, Vedula, Pavan, Tang, Hsin-Yao, Kashina, Anna, Dong, Dawei W

“…Arginylation is a post-translational modification mediated by the arginyltransferase (Ate1). We recently showed that conditional deletion of Ate1 in the…”
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Gβ3 is required for normal light ON responses and synaptic maintenance by Dhingra, Anuradha, Ramakrishnan, Hariharasubramanian, Neinstein, Adam, Fina, Marie E, Xu, Ying, Li, Jian, Chung, Daniel C, Lyubarsky, Arkady, Vardi, Noga

“…Heterotrimeric G-proteins, comprising Gα and Gβγ subunits, couple metabotropic receptors to various downstream effectors and contribute to assembling and…”
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Gβ 3 Is Required for Normal Light ON Responses and Synaptic Maintenance by Dhingra, Anuradha, Ramakrishnan, Hariharasubramanian, Neinstein, Adam, Fina, Marie E., Xu, Ying, Li, Jian, Chung, Daniel C., Lyubarsky, Arkady, Vardi, Noga

“…Heterotrimeric G-proteins, comprising Gα and Gβγ subunits, couple metabotropic receptors to various downstream effectors and contribute to assembling and…”
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Lack of mGluR6-related cascade elements leads to retrograde trans-synaptic effects on rod photoreceptor synapses via matrix-associated proteins by Tummala, Shanti R., Dhingra, Anuradha, Fina, Marie E., Li, Jian J., Ramakrishnan, Hariharasubramanian, Vardi, Noga

“…Heterotrimeric G‐proteins couple metabotropic receptors to downstream effectors. In retinal ON bipolar cells, Go couples the metabotropic receptor mGluR6 to…”
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Differential function of Gγ13 in rod bipolar and ON cone bipolar cells by Ramakrishnan, Hariharasubramanian, Dhingra, Anuradha, Tummala, Shanti R., Fina, Marie E., Li, Jian J., Lyubarsky, Arkady, Vardi, Noga

“…Key points The G‐protein‐mediated metabotropic glutamate receptor 6 (mGluR6) signalling cascade is critical for light responses in all retinal ON bipolar…”
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Probing neurochemical structure and function of retinal ON bipolar cells with a transgenic mouse by Dhingra, Anuradha, Sulaiman, Pyroja, Xu, Ying, Fina, Marie E., Veh, Rüdiger W., Vardi, Noga

“…Retinal ON bipolar cells make up about 70% of all bipolar cells. Glutamate hyperpolarizes these cells by binding to the metabotropic glutamate receptor mGluR6,…”
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Kir2.4 Surface Expression and Basal Current Are Affected by Heterotrimeric G-Proteins by Sulaiman, Pyroja, Xu, Ying, Fina, Marie E., Tummala, Shanti R., Ramakrishnan, Hariharasubramanian, Dhingra, Anuradha, Vardi, Noga

“…Kir2.4, a strongly rectifying potassium channel that is localized to neurons and is especially abundant in retina, was fished with yeast two-hybrid screen…”
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Cones respond to light in the absence of transducin β subunit by Nikonov, Sergei S, Lyubarsky, Arkady, Fina, Marie E, Nikonova, Elena S, Sengupta, Abhishek, Chinniah, Chidambaram, Ding, Xi-Qin, Smith, Robert G, Pugh, Jr, Edward N, Vardi, Noga, Dhingra, Anuradha

“…Mammalian cones respond to light by closing a cGMP-gated channel via a cascade that includes a heterotrimeric G-protein, cone transducin, comprising Gαt2, Gβ3…”
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Regulation of KCC2 and NKCC during development: Membrane insertion and differences between cell types by Zhang, Ling-Li, Fina, Marie E., Vardi, Noga

“…The developmental switch of GABA's action from excitation to inhibition is likely due to a change in intracellular chloride concentration from high to low…”
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Lack of mG luR6‐related cascade elements leads to retrograde trans‐synaptic effects on rod photoreceptor synapses via matrix‐associated proteins by Tummala, Shanti R., Dhingra, Anuradha, Fina, Marie E., Li, Jian J., Ramakrishnan, Hariharasubramanian, Vardi, Noga

“…Abstract Heterotrimeric G‐proteins couple metabotropic receptors to downstream effectors. In retinal ON bipolar cells, G o couples the metabotropic receptor mG…”
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Differential function of G[gamma]13 in rod bipolar and ON cone bipolar cells by Ramakrishnan, Hariharasubramanian, Dhingra, Anuradha, Tummala, Shanti R, Fina, Marie E, Li, Jian J, Lyubarsky, Arkady, Vardi, Noga

“…Key points The G-protein-mediated metabotropic glutamate receptor 6 (mGluR6) signalling cascade is critical for light responses in all retinal ON bipolar…”
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