Search Results - "Fina, Maggy"
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NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
Published in Nature immunology (01-03-2016)“…NEK7 is a serine-threonine kinase linked to mitosis. Beutler and colleagues show that NEK7 is required for assembly of the NLRP3 inflammasome and restricts…”
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Targeting QseC Signaling and Virulence for Antibiotic Development
Published in Science (American Association for the Advancement of Science) (22-08-2008)“…Many bacterial pathogens rely on a conserved membrane histidine sensor kinase, QseC, to respond to host adrenergic signaling molecules and bacterial signals in…”
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The role of ventral striatal cAMP signaling in stress-induced behaviors
Published in Nature neuroscience (01-08-2015)“…Changes in cAMP signalling in the brain influence mood and responses to stress. Here, the authors found that Cdk5 regulates cAMP degradation by PDE4…”
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Real-time resolution of point mutations that cause phenovariance in mice
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2015)“…With the wide availability of massively parallel sequencing technologies, genetic mapping has become the rate limiting step in mammalian forward genetics. Here…”
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MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses
Published in Science (American Association for the Advancement of Science) (19-12-2014)“…Multivalent molecules with repetitive structures including bacterial capsular polysaccharides and viral capsids elicit antibody responses through B cell…”
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PNAS Plus Significance Statements
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2015)Get full text
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Cardioprotective Effects of 70-kDa Heat Shock Protein in Transgenic Mice
Published in Proceedings of the National Academy of Sciences - PNAS (19-03-1996)“…Heat shock proteins are proposed to limit injury resulting from diverse environmental stresses, but direct metabolic evidence for such a cytoprotective…”
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Human heat shock protein 70 (hsp70) protects murine cells from injury during metabolic stress
Published in The Journal of clinical investigation (01-07-1993)“…Expression of heat shock protein 70 (hsp70) is stimulated during ischemia, but its proposed cytoprotective function during metabolic stress has remained…”
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