Search Results - "Fimbo, Adam"

A high-performance thin-layer chromatography densitometric method for the separation of isomeric ceftriaxone in powder for injection formulation by Mwamwitwa, Kissa W., Nyamweru, Bugusu, Iwodyah, Mohamed A., Sambu, Gerald, Nyondo, Goodluck G., Yondu, Emili, Fimbo, Adam M., Manyanga, Vicky, Sabiiti, Wilber, Shewiyo, Danstan H., Shearer, Morven C., Smith, Andrew D., Kaale, Eliangiringa A.

“…The aim of this study was to develop and validate a High-Performance Thin Layer Chromatographic (HPTLC) method for simultaneous determination of ceftriaxone…”
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Effectiveness of a structured stimulated spontaneous safety monitoring of medicines reporting program in strengthening pharmacovigilance system in Tanzania by Mwamwitwa, Kissa W., Fimbo, Adam M., Bukundi, Elias M., Nkayamba, Alex F., Buma, Deus, Muro, Eva P., Maganda, Betty A., Shewiyo, Danstan H., Shearer, Morven C., Smith, Andrew D., Kaale, Eliangiringa A.

“…Under-reporting of adverse drug events (ADEs) is a challenge facing developing countries including Tanzania. Given the high magnitude of under-reporting, it…”
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A retrospective cross-sectional study to determine chirality status of registered medicines in Tanzania by Mwamwitwa, Kissa W., Kaibere, Raphael M., Fimbo, Adam M., Sabitii, Wilber, Ntinginya, Nyanda E., Mmbaga, Blandina T., Shewiyo, Danstan H., Shearer, Morven C., Smith, Andrew D., Kaale, Eliangiringa A.

“…Medicines with a stereogenic center (asymmetric carbon) are mainly present as racemates with a mixture of equal amounts of enantiomers. One enantiomer may be…”
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Optimizing the East African Community's Medicines Regulatory Harmonization initiative in 2020-2022: A Roadmap for the Future by Arik, Mawien, Bamenyekanye, Emmanuel, Fimbo, Adam, Kabatende, Joseph, Kijo, Agnes Sitta, Simai, Burhani, Siyoi, Fred, Azatyan, Samvel, Ambali, Aggrey, Cooke, Emer, Mashingia, Jane H, Mwesigye, John Patrick, Ndomondo-Sigonda, Margareth, Sillo, Hiiti, Sonoiya, Stanley, Tanui, Paul, Ward, Mike, Delano, Thomas

“…Margareth Ndomondo-Sigonda outlines future challenges for the East African Medicines Regulatory Harmonization initiative…”
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Incidence and determinants of adverse events in individuals with HIV commencing Dolutegravir-based antiretroviral therapy in mainland Tanzania by Fimbo, Adam, Mwalwisi, Yonah H., Mwamwitwa, Kissa, Matiko, Damas, Mfinanga, Elirehema, Lyimo, Johnson, Sabasaba, Amon, Missago, Seth, Bukundi, Elias, Gotora, Goodluck, Respick, Dorice, Nkayamba, Alex, Masunga, Emmanuel, Mnkugwe, Rajabu Hussein, Kunambi, Peter P., Munishi, Castory, Musanhu, Christine Chiedza, Minzi, Omary M. S., Mlugu, Eulambius M.

“…Tanzania adopted a Dolutegravir (DTG)-based regimen as first-line treatment in 2019 following the World Health Organization recommendation. Data on the DTG…”
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Adverse Drug Reactions Resulting From the Use of Chiral Medicines Amoxicillin, Amoxicillin-Clavulanic Acid, and Ceftriaxone: A Mixed Prospective-Retrospective Cohort Study by Mwamwitwa, Kissa W, Bukundi, Elias M, Maganda, Betty A, Munishi, Castory, Fimbo, Adam M, Buma, Deus, Muro, Eva P, Sabiiti, Wilber, Shewiyo, Danstan H, Shearer, Morven C, Smith, Andrew D, Kaale, Eliangiringa A

“…The use of chiral medicines (possessing center(s) of asymmetric carbon) may cause adverse drug reactions (ADRs). The safety assurance of these medicines is…”
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Efficacy of ivermectin and albendazole combination in suppressing transmission of lymphatic filariasis following mass administration in Tanzania: a prospective cohort study by Fimbo, Adam M, Mnkugwe, Rajabu Hussein, Mlugu, Eulambius Mathias, Kunambi, Peter P, Malishee, Alpha, Minzi, Omary M S, Kamuhabwa, Appolinary A R, Aklillu, Eleni

“…Preventive chemotherapy with ivermectin and albendazole (IA) in mass drug administration (MDA) programs for all at-risk populations is the core public health…”
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Strengthening regulation for medical products in Tanzania: An assessment of regulatory capacity development, 1978-2020 by Fimbo, Adam M, Sillo, Hiiti B, Nkayamba, Alex, Kisoma, Sunday, Mwalwisi, Yonah Hebron, Idris, Rafiu, Asiimwe, Sarah, Githendu, Patrick, Ogbuoji, Osondu, Morrison, Linden, Bump, Jesse B, Kaale, Eliangiringa

“…Improving medicines regulation can lead to better population health, but how this process works in low- and middle-income countries remains underexplored…”
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Safety and Tolerability of Ivermectin and Albendazole Mass Drug Administration in Lymphatic Filariasis Endemic Communities of Tanzania: A Cohort Event Monitoring Study by Fimbo, Adam M, Minzi, Omary Mashiku, Mmbando, Bruno P, Gurumurthy, Parthasarathi, Kamuhabwa, Appolinary A R, Aklillu, Eleni

“…Ivermectin and albendazole (IA) combination preventive chemotherapy to all at-risk populations is deployed to eliminate lymphatic filariasis. Although safety…”
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Population pharmacokinetics of ivermectin after mass drug administration in lymphatic filariasis endemic communities of Tanzania by Fimbo, Adam M., Mlugu, Eulambius M., Kitabi, Eliford Ngaimisi, Kulwa, Gerald S., Iwodyah, Mohammed A., Mnkugwe, Rajabu Hussein, Kunambi, Peter P., Malishee, Alpha, Kamuhabwa, Appolinary A. R., Minzi, Omary M., Aklillu, Eleni

“…Ivermectin (IVM) is a drug of choice used with albendazole for mass drug administration (MDA) to halt transmission of lymphatic filariasis. We investigated IVM…”
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Utilization Trends of Phosphodiesterase Type-5 Inhibitors for Erectile Dysfunction Between 2019 and 2023 in Tanzania by Sangeda, Raphael Z, Kadinde, Auleria W, Masatu, Cassian F, Mwalwisi, Yonah Hebron, Yahya-Malima, Khadija I, Fimbo, Adam M

“…Introduction Erectile dysfunction (ED) profoundly affects millions of people globally, including interfering with mental health and quality of life…”
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Post marketing surveillance of selected veterinary medicines in Tanzania mainland by Fimbo, Adam M, Maganda, Betty A, Mwamwitwa, Kissa W, Mwanga, Itikija E, Mbekenga, Engelbert B, Kisenge, Seth, Mziray, Sophia A, Kulwa, Gerald S, Mwalwisi, Yonah H, Shewiyo, Danstan H

“…Veterinary medicines have been widely used for the prevention and treatment of animal diseases. Globally, the veterinary medicine industry is growing. However,…”
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National Antibiotics Utilization Trends for Human Use in Tanzania from 2010 to 2016 Inferred from Tanzania Medicines and Medical Devices Authority Importation Data by Sangeda, Raphael Zozimus, Saburi, Habibu Ally, Masatu, Faustine Cassian, Aiko, Beatrice Godwin, Mboya, Erick Alexander, Mkumbwa, Sonia, Bitegeko, Adonis, Mwalwisi, Yonah Hebron, Nkiligi, Emmanuel Alphonse, Chambuso, Mhina, Sillo, Hiiti Baran, Fimbo, Adam M, Horumpende, Pius Gerald

“…Antimicrobial use (AMU) is one of the major drivers of emerging antimicrobial resistance (AMR). The surveillance of AMU, which is a pillar of AMR stewardship…”
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Quality of selected anti-retroviral medicines: Tanzania Mainland market as a case study by Mziray, Sophia, Maganda, Betty A, Mwamwitwa, Kissa, Fimbo, Adam M, Kisenge, Seth, Sambu, Gerald, Mwalwisi, Yonah H, Bitegeko, Adonis, Alphonce, Emmanuel, Khea, Akida, Shewiyo, Danstan H, Kaale, Eliangiringa

“…Antiretroviral drugs (ARVs) have significantly reduced morbidity, mortality and improved the quality of life of people living with HIV infection. Poor quality…”
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Antibiotic utilization patterns in Tanzania: a retrospective longitudinal study comparing pre- and intra-COVID-19 pandemic era using Tanzania Medicines and Medical Devices Authority data by Sangeda, Raphael Z, William, Sahani M, Masatu, Faustine C, Bitegeko, Adonis, Mwalwisi, Yonah H, Nkiligi, Emmanuel A, Horumpende, Pius G, Fimbo, Adam M

“…Antimicrobial resistance (AMR) is a growing public health concern globally, and misuse of antibiotics is a major contributor. This study investigated…”
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Trends in Utilization of Emergency Contraceptives in Tanzania: A Retrospective Longitudinal Study From 2018 to 2023 by Kadinde, Auleria W, Sangeda, Raphael Z, Mwenda, Lucy, Yahya-Malima, Khadija I, Masatu, Cassian F, Mwalwisi, Yonah H, Fimbo, Adam M

“…Introduction Emergency contraceptives (ECs) are a critical method for preventing unwanted pregnancies following unprotected sexual intercourse. However,…”
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Evaluation of the Good Review Practices of Countries Participating in the Southern African Development Community: Alignment and Strategies for Moving Forward by Sithole, Tariro, Mahlangu, Gugu, Capote, Velma, Sitoie, Tania, Shifotoka, Saren, Gaeseb, Johannes, Padayachee, Silverani, Sehloho, Tohlang, Khea, Akida, Fimbo, Adam, Munkombwe, Zuma, Mwale, Bernice, Salek, Sam, Walker, Stuart

“…National medicines regulatory agencies are faced with challenges including limited resources and technical capacity, resulting in countries collaborating and…”
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Evaluation of the Review Models and Approval Timelines of Countries Participating in the Southern African Development Community: Alignment and Strategies for Moving Forward by Sithole, Tariro, Mahlangu, Gugu, Capote, Velma, Sitoie, Tania, Shifotoka, Saren, Gaeseb, Johannes, Danks, Lorraine, Nkambule, Portia, Juma, Alex, Fimbo, Adam, Munkombwe, Zuma, Mwale, Bernice, Salek, Sam, Walker, Stuart

“…Regulatory reliance, harmonization and work sharing have grown over the last few years, resulting in greater sharing of work and information among regulators,…”
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Prevalence and Correlates of Lymphatic Filariasis Infection and Its Morbidity Following Mass Ivermectin and Albendazole Administration in Mkinga District, North-Eastern Tanzania by Fimbo, Adam M, Minzi, Omary M S, Mmbando, Bruno P, Barry, Abbie, Nkayamba, Alex F, Mwamwitwa, Kissa W, Malishee, Alpha, Seth, Misago D, Makunde, Williams H, Gurumurthy, Parthasarathi, Lusingu, John P A, Kamuhabwa, Appolinary A R, Aklillu, Eleni

“…Lymphatic filariasis (LF) is a neglected tropical disease targeted for elimination as public health problem through morbidity management and preventive annual…”
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Safety Profile of Artemether-Lumefantrine: A Cohort Event Monitoring Study in Public Health Facilities in Tanzania by Mssusa, Alambo K., Fimbo, Adam M., Nkayamba, Alex F., Irunde, Henry F., Sillo, Hiiti B., Shewiyo, Danstan H., Hill, Geraldine, Minzi, Omary M.

“…Background and Objective Artemisinin combination therapies such as artemether-lumefantrine (AL) are effective for first-line treatment of uncomplicated acute…”
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