Search Results - "Filutowicz, Hanna I"

Safety, Tolerability, and Immunogenicity of a Recombinant, Genetically Engineered, Live-Attenuated Vaccine against Canine Blastomycosis by Wüthrich, Marcel, Krajaejun, Theerapong, Shearn-Bochsler, Valerie, Bass, Chris, Filutowicz, Hanna I, Legendre, Alfred M, Klein, Bruce S

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Limited Model Antigen Expression by Transgenic Fungi Induces Disparate Fates during Differentiation of Adoptively Transferred T Cell Receptor Transgenic CD4+ T Cells: Robust Activation and Proliferation with Weak Effector Function during Recall by Wüthrich, Marcel, Ersland, Karen, Pick-Jacobs, John C, Gern, Benjamin H, Frye, Christopher A, Sullivan, Thomas D, Brennan, Meghan B, Filutowicz, Hanna I, O'Brien, Kevin, Korthauer, Keegan D, Schultz-Cherry, Stacey, Klein, Bruce S

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Vβ1⁺ Jβ1.1⁺/Vα2⁺ Jα49⁺ CD4⁺ T Cells Mediate Resistance against Infection with Blastomyces dermatitidis by Wüthrich, Marcel, Filutowicz, Hanna I, Allen, Holly L, Deepe, George S, Klein, Bruce S

“…Immunization with a cell wall/membrane (CW/M) and yeast cytosol extract (YCE) crude antigen from Blastomyces dermatitidis confers T-cell-mediated resistance…”
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Requisite Elements in Vaccine Immunity to Blastomyces dermatitidis: Plasticity Uncovers Vaccine Potential in Immune-Deficient Hosts by Wuthrich, Marcel, Filutowicz, Hanna I, Warner, Tom, Klein, Bruce S

“…Understanding fundamental mechanisms of vaccine immunity will allow proper use and optimization of vaccines. Vaccination with a genetically engineered, live,…”
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A TCR transgenic mouse reactive with multiple systemic dimorphic fungi by Wüthrich, Marcel, Hung, Chiung Yu, Gern, Ben H, Pick-Jacobs, John C, Galles, Kevin J, Filutowicz, Hanna I, Cole, Garry T, Klein, Bruce S

“…Dimorphic fungi collectively account for 5-10 million new infections annually worldwide. Ongoing efforts seek to clarify mechanisms of cellular resistance to…”
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Vaccine immunity to pathogenic fungi overcomes the requirement for CD4 help in exogenous antigen presentation to CD8+ T cells: implications for vaccine development in immune-deficient hosts by Wuthrich, Marcel, Filutowicz, Hanna I, Warner, Tom, Deepe, Jr, George S, Klein, Bruce S

“…Systemic fungal infections with primary and opportunistic pathogens have become increasingly common and represent a growing health menace in patients with AIDS…”
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Differential Requirements of T Cell Subsets for CD40 Costimulation in Immunity to Blastomyces dermatitidis by Wuthrich, Marcel, Fisette, Phil L, Filutowicz, Hanna I, Klein, Bruce S

“…Cell-mediated immunity and production of type 1 cytokines are the main defenses against pathogenic fungi. Ligation of CD40 by CD40L on T cells is critical for…”
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Analysis of non-adhesive pathogenic mechanisms of BAD1 on Blastomyces dermatitidis by Wüthrich, Marcel, Finkel-Jimenez, Beatriz, Brandhorst, Tristan T., Filutowicz, Hanna I., Warner, Tom, Klein, Bruce S.

“…The adhesin BAD1 is required for virulence of Blastomyces dermatitidis in a pulmonary model of infection. Herein, we explored mechanisms by which BAD1 enhances…”
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A T-cell receptor transgenic mouse reactive with multiple systemic dimorphic fungi by Wüthrich, Marcel, Hung, Chiung Yu, Gern, Ben H., Pick-Jacobs, John C., Galles, Kevin J., Filutowicz, Hanna I., Cole, Garry T., Klein, Bruce S.

“…Dimorphic fungi collectively account for 5 to 10 million new infections annually worldwide. Ongoing efforts seek to clarify mechanisms of cellular resistance…”
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Mutation of the WI-1 gene yields an attenuated blastomyces dermatitidis strain that induces host resistance by Wüthrich, M, Filutowicz, H I, Klein, B S

“…Systemic fungal infections are becoming more common and difficult to treat, and vaccine prevention is not available. Pulmonary infection with the dimorphic…”
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V beta1+ J beta1.1+/V alpha2+ J alpha49+ CD4+ T cells mediate resistance against infection with Blastomyces dermatitidis by Wüthrich, Marcel, Filutowicz, Hanna I, Allen, Holly L, Deepe, George S, Klein, Bruce S

“…Immunization with a cell wall/membrane (CW/M) and yeast cytosol extract (YCE) crude antigen from Blastomyces dermatitidis confers T-cell-mediated resistance…”
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V{beta}1 super(+) J{beta}1.1 super(+)/V alpha 2 super(+) J alpha 49 super(+) CD4 super(+) T Cells Mediate Resistance against Infection with Blastomyces dermatitidis by Wuethrich, Marcel, Filutowicz, Hanna I, Allen, Holly L, Deepe, George S, Klein, Bruce S

“…Immunization with a cell wall/membrane (CW/M) and yeast cytosol extract (YCE) crude antigen from Blastomyces dermatitidis confers T-cell-mediated resistance…”
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Vaccine Immunity to Pathogenic Fungi Overcomes the Requirement for CD4 Help in Exogenous Antigen Presentation to CD8+ T Cells by Wüthrich, Marcel, Filutowicz, Hanna I., Warner, Tom, Deepe, George S., Klein, Bruce S.

“…Systemic fungal infections with primary and opportunistic pathogens have become increasingly common and represent a growing health menace in patients with AIDS…”
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