Search Results - "Filtenborg Hocke, Emma"
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A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Published in eLife (25-01-2024)“…The pathogenesis of severe malaria involves cytoadhesive microvascular sequestration of infected erythrocytes, mediated by erythrocyte membrane protein 1…”
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Lack of selection of antimalarial drug resistance markers after intermittent preventive treatment of schoolchildren (IPTsc) against malaria in northeastern Tanzania
Published in International journal of infectious diseases (01-09-2024)“…•The prevalence of markers of drug resistance was compared pre- and post-IPTsc.•No significant difference in prevalence of markers was observed (e.g.,…”
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Identification of the PfK13 mutations R561H and P441L in the Democratic Republic of Congo
Published in International journal of infectious diseases (01-02-2024)“…Partial artemisinin resistance, mediated by Plasmodium falciparum K13 (PfK13) mutations, has been confirmed in certain areas of East Africa that are…”
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Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology
Published in PLoS medicine (09-05-2024)“…Recently revised WHO guidelines on malaria chemoprevention have opened the door to more tailored implementation. Countries face choices on whether to replace…”
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Parasite clearance and protection from Plasmodium falciparum infection (PCPI): a three-arm, parallel, double-blinded, placebo-controlled, randomised trial of presumptive sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine plus amodiaquine versus artesunate monotherapy among asymptomatic children 3-5 years of age in Cameroon
Published in BMC infectious diseases (26-09-2024)“…The World Health Organization 2022 malaria chemoprevention guidelines recommend providing a full course of antimalarial treatment at pre-defined intervals,…”
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Evolution of Plasmodium falciparum antimalarial drug resistance markers post-adoption of artemisinin-based combination therapies in Yaounde, Cameroon
Published in International journal of infectious diseases (01-07-2023)“…•Drug resistance markers data were compared before and after the adaption of artemisinin-based combination therapies.•The Pfcrt K76T and Pfmdr1 N86Y mutations…”
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Unravelling the Phylogeny of a Common Intestinal Protist: Intrageneric Diversity of Endolimax
Published in Protist (01-10-2022)“…Endolimax nana is a common endobiont of the human intestine, but members of the genus have also been reported in non-human hosts and in non-intestinal organs…”
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8
Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology
Published in PLoS medicine (01-05-2024)Get full text
Journal Article -
9
A novel computational pipeline for var gene expression augments the discovery of changes in the Plasmodium falciparum transcriptome during transition from in vivo to short-term in vitro culture
Published in eLife (25-01-2024)“…The pathogenesis of severe Plasmodium falciparum malaria involves cytoadhesive microvascular sequestration of infected erythrocytes, mediated by P. falciparum…”
Get full text
Journal Article