Search Results - "Filloon, Thomas"

Pexelizumab, an anti-C5 complement antibody, as adjunctive therapy to primary percutaneous coronary intervention in acute Myocardial Infarction: The COMplement inhibition in Myocardial infarction treated with Angioplasty (COMMA) trial by GRANGER, Christopher B, MAHAFFEY, Kenneth W, ARMSTRONG, Paul W, WEAVER, W. Douglas, THEROUX, Pierre, HOCHMAN, Judith S, FILLOON, Thomas G, ROLLINS, Scott, TODARO, Thomas G, NICOLAU, Jose C, RUZYLLO, Witold

“…Complement, activated during myocardial ischemia and reperfusion, causes myocardial damage through multiple processes. The COMplement inhibition in Myocardial…”
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Effect of pexelizumab, an anti-C5 complement antibody, as adjunctive therapy to fibrinolysis in acute Myocardial Infarction: The COMPlement inhibition in myocardial infarction treated with thromboLYtics (COMPLY) trial by MAHAFFEY, Kenneth W, GRANGER, Christopher B, ARMSTRONG, Paul W, NICOLAU, Jose C, RUZYLLO, Witold, WEAVER, W. Douglas, THEROUX, Pierre, HOCHMAN, Judith S, FILLOON, Thomas G, MOJCIK, Christopher F, TODARO, Thomas G

“…Complement activation mediates myocardial damage that occurs during ischemia and reperfusion through multiple pathways. We performed 2 separate, parallel,…”
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Increased creatine kinase MB level predicts postoperative mortality after cardiac surgery independent of new Q waves by Ramsay, James, Shernan, Stanton, Fitch, Jane, Finnegan, Paul, Todaro, Thomas, Filloon, Thomas, Nussmeier, Nancy A.

“…Recent consensus statements recommend cardiac enzyme release as the essential criterion for diagnosing myocardial infarction. However, the outcome implications…”
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Macular pigment optical density in a midwestern sample by Ciulla, T A, Curran-Celantano, J, Cooper, D A, Hammond, Jr, B R, Danis, R P, Pratt, L M, Riccardi, K A, Filloon, T G

“…To assess the distribution of the macular pigments (MPs) lutein (L) and zeaxanthin (Z) in a healthy sample more representative of the general population than…”
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Effect of pexelizumab on mortality in patients with acute myocardial infarction or undergoing coronary artery bypass surgery: A systematic overview by Mahaffey, Kenneth W., Van de Werf, Frans, Shernan, Stanton K., Granger, Christopher B., Verrier, Edward D., Filloon, Thomas G., Todaro, Thomas G., Adams, Peter X., Levy, Jerrold H., Hasselblad, Vic, Armstrong, Paul W.

“…Recent trials evaluating the C5 complement inhibitor, pexelizumab, have shown that modulation of inflammation during ischemia/reperfusion in patients with…”
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Performance Equivalence and Validation of the Soleris Automated System for Quantitative Microbial Content Testing Using Pure Suspension Cultures by Limberg, Brian J, Johnstone, Kevin, Filloon, Thomas, Catrenich, Carl

“…Using United States Pharmacopeia-National Formulary (USP-NF) general method guidance, the Soleris(®) automated system and reagents (Nonfermenting Total Viable…”
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Epidermal changes associated with symptomatic resolution of dandruff: biomarkers of scalp health by Kerr, Kathy, Darcy, Trevor, Henry, James, Mizoguchi, Haruko, Schwartz, James R., Morrall, Stephen, Filloon, Thomas, Wimalasena, Rohan, Fadayel, Gina, Mills, Kevin J.

“…Background  Dandruff is a common scalp condition characterized by flakes, pruritus and sometimes mild erythema. These symptoms reflect underlying…”
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Comparison of p-fluoroketorolac and [ 18O 3]ketorolac for use as internal standards for the determination of ketorolac by gas chromatography/mass spectrometry (GC/MS) by Eichhold, Thomas H, Filloon, Thomas G, Wehmeyer, Kenneth R

“…A chemical and a stable-isotope analog, p-fluoroketorolac and [ 18O 3]ketorolac respectively, were directly compared for applicability as internal standards…”
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Scalp Stratum Corneum Histamine Levels: Novel Sampling Method Reveals Association with Itch Resolution in Dandruff/Seborrhoeic Dermatitis Treatment by KERR, Kathy, SCHWARTZ, James R, FILLOON, Thomas, FIENO, Angela, WEHMEYER, Ken, SZEPIETOWSKI, Jacek C, MILLS, Kevin J

“…Dandruff and seborrhoeic dermatitis are accompanied by bothersome itch. We have established a novel non-invasive methodology to sample histamine levels in the…”
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Impact of pexelizumab, an anti-C5 complement antibody, on total mortality and adverse cardiovascular outcomes in cardiac surgical patients undergoing cardiopulmonary bypass by Shernan, Stanton K, Fitch, Jane C.K, Nussmeier, Nancy A, Chen, John C, Rollins, Scott A, Mojcik, Christopher F, Malloy, Kevin J, Todaro, Thomas G, Filloon, Thomas, Boyce, Steven W, Gangahar, Deepak M, Goldberg, Michael, Saidman, Lawrence J, Mangano, Dennis T

“…During cardiac surgery requiring cardiopulmonary bypass, pro-inflammatory complement pathways are activated by exposure of blood to bio-incompatible surfaces…”
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Gastrointestinal Symptoms Following Consumption of Olestra or Regular Triglyceride Potato Chips: A Controlled Comparison by Cheskin, Lawrence J, Miday, Robert, Zorich, Nora, Filloon, Thomas

“…CONTEXT.— Olestra, a nonabsorbable, energy-free fat substitute used in snack foods, has been anecdotally reported to cause gastrointestinal (GI) adverse…”
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Gastrointestinal Symptoms Following Olestra Consumption—Reply by Cheskin, Lawrence J, Zorich, Nora, Miday, Robert, Filloon, Thomas

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Impact of pexelizumab, an anti-C5 complement antibody, on total mortality and adverse cardiovascular outcomes in cardiac surgical patients undergoing cardiopulmonary bypass. Commentary by SHERNAN, Stanton K, FITCH, Jane C. K, GANGAHAR, Deepak M, GOLDBERG, Michael, SAIDMAN, Lawrence J, MANGANO, Dennis T, SVEDJEHOLM, Rolf, NUSSMEIER, Nancy A, CHEN, John C, ROLLINS, Scott A, MOJCIK, Christopher F, MALLOY, Kevin J, TODARO, Thomas G, FILLOON, Thomas, BOYCE, Steven W

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Olestra consumption is not associated with macular pigment optical density in a cross-sectional volunteer sample in Indianapolis by Cooper, D A, Curran-Celentano, J, Ciulla, T A, Hammond, Jr, B R, Danis, R B, Pratt, L M, Riccardi, K A, Filloon, T G

“…The associations between the intake of the fat-substitute olestra and the concentrations of macular carotenoid pigments and serum lutein and zeaxanthin were…”
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Estimating the minimum therapeutically effective dose of a compound via regression modelling and percentile estimation by Filloon, T G

“…Estimation of the minimum effective dose (MED) of a compound from a typical placebo-controlled dose-response study can be carried out in several ways. Current…”
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Gastrointestinal symptoms in 3181 volunteers ingesting snack foods containing Olestra or triglycerides : A 6-week randomized, placebo-controlled trial by SANDLER, R. S, ZORICH, N. L, FILLOON, T. G, WISEMAN, H. B, LIETZ, D. J, BROCK, M. H, ROYER, M. G, MIDAY, R. K

“…Olestra is a nonabsorbable, energy-free fat substitute. Because it is not absorbed, it may cause digestive symptoms when consumed in large amounts. To compare…”
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Improving the sensitivity of in vitro skin penetration experiments by KASTING, G. B, FILLOON, T. G, FRANCIS, W. R, MEREDITH, M. P

“…The institution of a readily-implemented sample screening and data handling procedure for in vitro skin penetration studies yields substantial improvements in…”
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Randomized, Double-Blind, Placebo-Controlled, Consumer Rechallenge Test of Olean Salted Snacks by Zorich, Nora L., Biedermann, David, Riccardi, Karen A., Bishop, Lori J., Filloon, Thomas G.

“…Olestra is a zero-calorie fat substitute that is neither digested nor absorbed. A randomized, double-blind, placebo-controlled, within-subject, crossover…”
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Improved curve estimation with smoothing splines through local cross-validation by Filloon, Thomas Gene

“…Much attention has been given recently to the nonparametric estimation of regression functions (or curves). Various methods have been shown to yield consistent…”
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Improved curve estimation with smoothing splines through local cross-validation by Filloon, Thomas Gene

“…Much attention has been given recently to the nonparametric estimation of regression functions (or curves). Various methods have been shown to yield consistent…”
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