Search Results - "Fillat, Marı́a F"

The FUR (ferric uptake regulator) superfamily: Diversity and versatility of key transcriptional regulators by Fillat, María F.

“…•FUR proteins are a versatile family of regulators with a common structural fold.•Cross-talk between FUR proteins occurs in many bacteria.•Fur can work as…”
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Heme binds to and inhibits the DNA-binding activity of the global regulator FurA from Anabaena sp. PCC 7120 by Hernández, José A., Peleato, M.Luisa, Fillat, Marı́a F., Bes, M.Teresa

“…Heme is an iron-containing cofactor that aside from serving as the active group of essential proteins is a key element in the control of many molecular and…”
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Fur-like proteins: Beyond the ferric uptake regulator (Fur) paralog by Sevilla, Emma, Bes, M. Teresa, Peleato, M. Luisa, Fillat, María F.

“…Proteins belonging to the FUR (ferric uptake regulator) family are the cornerstone of metalloregulation in most prokaryotes. Although numerous reviews have…”
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Microcystin-LR Binds Iron, and Iron Promotes Self-Assembly by Ceballos-Laita, Laura, Marcuello, Carlos, Lostao, Anabel, Calvo-Begueria, Laura, Velazquez-Campoy, Adrián, Bes, María Teresa, Fillat, María F, Peleato, María-Luisa

“…The microcystin-producing Microcystis aeruginosa PCC 7806 and its close strain, the nonproducing Microcystis aeruginosa PCC 7005, grow similarly in the…”
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Expanding the FurC (PerR) regulon in Anabaena (Nostoc) sp. PCC 7120: Genome-wide identification of novel direct targets uncovers FurC participation in central carbon metabolism regulation by Sarasa-Buisan, Cristina, Guío, Jorge, Peleato, M Luisa, Fillat, María F, Sevilla, Emma

“…FurC (PerR, Peroxide Response Regulator) from Anabaena sp. PCC 7120 (also known as Nostoc sp. PCC 7120) is a master regulator engaged in the modulation of…”
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Identifying potential novel drugs against Helicobacter pylori by targeting the essential response regulator HsrA by González, Andrés, Salillas, Sandra, Velázquez-Campoy, Adrián, Espinosa Angarica, Vladimir, Fillat, María F., Sancho, Javier, Lanas, Ángel

“…The increasing antibiotic resistance evolved by Helicobacter pylori has alarmingly reduced the eradication rates of first-line therapies. To overcome the…”
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Novel Drug-like HsrA Inhibitors Exhibit Potent Narrow-Spectrum Antimicrobial Activities against Helicobacter pylori by Casado, Javier, Olivan-Muro, Irene, Algarate, Sonia, Chueca, Eduardo, Salillas, Sandra, Velázquez-Campoy, Adrián, Piazuelo, Elena, Fillat, María F, Sancho, Javier, Lanas, Ángel, González, Andrés

“…infection constitutes a silent pandemic of global concern. In the last decades, the alarming increase in multidrug resistance evolved by this pathogen has led…”
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An ancient bacterial zinc acquisition system identified from a cyanobacterial exoproteome by Sarasa-Buisan, Cristina, Ochoa de Alda, Jesús A G, Velázquez-Suárez, Cristina, Rubio, Miguel Ángel, Gómez-Baena, Guadalupe, Fillat, María F, Luque, Ignacio

“…Bacteria have developed fine-tuned responses to cope with potential zinc limitation. The Zur protein is a key player in coordinating this response in most…”
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FurC (PerR) contributes to the regulation of peptidoglycan remodeling and intercellular molecular transfer in the cyanobacterium Anabaena sp. strain PCC 7120 by Sarasa-Buisan, Cristina, Nieves-Morión, Mercedes, Arévalo, Sergio, Helm, Richard F, Sevilla, Emma, Luque, Ignacio, Fillat, María F

“…Microbial extracellular proteins and metabolites provide valuable information concerning how microbes adapt to changing environments. In cyanobacteria, dynamic…”
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Expanding the Role of FurA as Essential Global Regulator in Cyanobacteria by González, Andrés, Bes, M Teresa, Peleato, M Luisa, Fillat, María F

“…In the nitrogen-fixing heterocyst-forming cyanobacterium Anabaena sp. PCC 7120, the ferric uptake regulator FurA plays a global regulatory role. Failures to…”
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FurC (PerR) from Anabaena sp. PCC7120: a versatile transcriptional regulator engaged in the regulatory network of heterocyst development and nitrogen fixation by Sarasa‐Buisan, Cristina, Guio, Jorge, Broset, Esther, Peleato, M. Luisa, Fillat, María F., Sevilla, Emma

“…Summary FurC (PerR) from Anabaena sp. PCC7120 was previously described as a key transcriptional regulator involved in setting off the oxidative stress…”
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Functional characterization of Fur from the strict anaerobe Clostridioides difficile provides insight into its redox‐driven regulatory capacity by Fernández‐Otal, Ángela, Guío, Jorge, Sarasa‐Buisan, Cristina, Peleato, M. Luisa, Fillat, María F., Lanas, Ángel, Bes, M. Teresa

“…Clostridioides (formerly Clostridium) difficile is a leading cause of infectious diarrhea associated with antibiotic therapy. The ability of this anaerobic…”
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Functional Replacement of Ferredoxin by a Cyanobacterial Flavodoxin in Tobacco Confers Broad-Range Stress Tolerance by Tognetti, Vanesa B, Palatnik, Javier F, Fillat, María F, Melzer, Michael, Hajirezaei, Mohammad-Reza, Valle, Estela M, Carrillo, Néstor

“…Chloroplast ferredoxin (Fd) plays a pivotal role in plant cell metabolism by delivering reducing equivalents to various essential oxidoreductive pathways. Fd…”
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The FurA regulon in Anabaena sp. PCC 7120: in silico prediction and experimental validation of novel target genes by González, Andrés, Angarica, Vladimir Espinosa, Sancho, Javier, Fillat, María F.

“…In the filamentous cyanobacterium Anabaena sp. PCC 7120, the ferric uptake regulator FurA functions as a global transcriptional regulator. Despite several…”
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Global Lrp regulator protein from Haloferax mediterranei: Transcriptional analysis and structural characterization by Matarredona, Laura, García-Bonete, María-José, Guío, Jorge, Camacho, Mónica, Fillat, María F., Esclapez, Julia, Bonete, María-José

“…Haloferax mediterranei, an extreme halophilic archaeon thriving in hypersaline environments, has acquired significant attention in biotechnological and…”
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FurA is the master regulator of iron homeostasis and modulates the expression of tetrapyrrole biosynthesis genes in Anabaena sp. PCC 7120 by González, Andrés, Bes, M. Teresa, Valladares, Ana, Peleato, M. Luisa, Fillat, María F.

“…Summary Knowledge on the regulatory mechanisms controlling iron homeostasis in cyanobacteria is limited. In Anabaena sp. PCC 7120, the ferric uptake regulator…”
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Molecular basis for the integration of environmental signals by FurB from Anabaena sp. PCC 7120 by Sein-Echaluce, Violeta C, Pallarés, María Carmen, Lostao, Anabel, Yruela, Inmaculada, Velázquez-Campoy, Adrián, Luisa Peleato, M, Fillat, María F

“…FUR (Ferric uptake regulator) proteins are among the most important families of transcriptional regulators in prokaryotes, often behaving as global regulators…”
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Transcriptional regulators: valuable targets for novel antibacterial strategies by González, Andrés, Fillat, María F, Lanas, Ángel

“…Antibiotics have saved millions of lives over the past decades. However, the accumulation of so many antibiotic resistance genes by some clinically relevant…”
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Metal binding and oligomerization properties of FurC (PerR) from Anabaena sp. PCC7120: an additional layer of regulation? by Sarasa-Buisan, Cristina, Emonot, Etienne, Martínez-Júlvez, Marta, Sevilla, Emma, Velázquez-Campoy, Adrián, Crouzy, Serge, Bes, M Teresa, Michaud-Soret, Isabelle, Fillat, María F

“…Abstract Metal and redox homeostasis in cyanobacteria is tightly controlled to preserve the photosynthetic machinery from mismetallation and minimize cell…”
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Enhanced plant tolerance to iron starvation by functional substitution of chloroplast ferredoxin with a bacterial flavodoxin by Tognetti, Vanesa B, Zurbriggen, Matias D, Morandi, Eligio N, Fillat, María F, Valle, Estela M, Hajirezaei, Mohammad-Reza, Carrillo, Néstor

“…Iron limitation affects one-third of the cultivable land on Earth and represents a major concern for agriculture. It causes decline of many photosynthetic…”
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