Search Results - "Filippova, Natalia"

The RNA-binding protein HuR promotes glioma growth and treatment resistance by Filippova, Natalia, Yang, Xiuhua, Wang, Yimin, Gillespie, G Yancey, Langford, Cathy, King, Peter H, Wheeler, Crystal, Nabors, L Burt

“…Posttranscriptional regulation is a critical control point for the expression of genes that promote or retard tumor growth. We previously found that the…”
Get full text

Phosphoregulation of the RNA-binding Protein Hu Antigen R (HuR) by Cdk5 Affects Centrosome Function by Filippova, Natalia, Yang, Xiuhua, King, Peter, Nabors, L.Burt

“…Hu antigen R (HuR) is an mRNA-binding protein belonging to the ELAV family. It is highly expressed in cancer and involved in cell survival and proliferation…”
Get full text

Redescription of Dermacentor everestianus Hirst (Acari: Ixodidae), a Parasite of Mammals in Mountains of China and Nepal with Synonymization of D. abaensis Teng and D. birulai Olenev by Apanaskevich, Dmitry A, Duan, Wei, Apanaskevich, Maria A, Filippova, Natalia A, Chen, Jun

“…Examination of extensive Dermacentor Koch, 1844 holdings stored in several major tick collections allowed us to re-evaluate the taxonomic content of…”
Get full text

Yuri Sergeevich Balashov: 25 December 1931–28 September 2012 by Filippova, Dr. Natalia A

Get full text

Topical bacterial lipopolysaccharide application affects inflammatory response and promotes wound healing by Kostarnoy, Alexey V, Gancheva, Petya G, Logunov, Denis Y, Verkhovskaya, Lyudmila V, Bobrov, Maxim A, Scheblyakov, Dmitry V, Tukhvatulin, Amir I, Filippova, Natalia E, Naroditsky, Boris S, Gintsburg, Alexandr L

“…The mechanisms underlying the complex and multistage wound-healing process are not yet completely understood. One of the most important and intriguing…”
Get more information

The genus Hyalomma Koch, 1844. x. redescription of all parasitic stages of H. (Euhyalomma) scupense Schulze, 1919 (= H. detritum Schulze) (Acari: Ixodidae) and notes on its biology by Apanaskevich, Dmitry A, Filippova, Natalia A, Horak, Ivan G

“…Taxonomic uncertainty as to the identities of Hyalomma (Euhyalomma) scupense Schulze, 1919 and Hyalomma detritum Schulze, 1919 has existed for nearly 85 years…”
Get full text

Growth factor dependent regulation of centrosome function and genomic instability by HuR by Filippova, Natalia, Yang, Xiuhua, Nabors, Louis Burt

“…The mRNA binding protein HuR is over expressed in cancer cells and contributes to disease progression through post-transcriptional regulation of mRNA. The…”
Get full text

Middle-Upper Miocene stratigraphy of the Taman Peninsula, Eastern Paratethys by Radionova Eleonora, Golovina Larisa, Filippova Natalia, Trubikhin Valery, Popov Sergey, Goncharova Irina, Vernigorova Yulia, Pinchuk Tatiana

Get full text

Amyotrophic Lateral Sclerosis-linked Mutant SOD1 Sequesters Hu Antigen R (HuR) and TIA-1-related Protein (TIAR) by Lu, Liang, Wang, Shuying, Zheng, Lei, Li, Xuelin, Suswam, Esther A., Zhang, Xiaowen, Wheeler, Crystal G., Nabors, L.B., Filippova, Natalia, King, Peter H.

“…Down-regulation of vascular endothelial growth factor (VEGF) in the mouse leads to progressive and selective degeneration of motor neurons similar to…”
Get full text

ELAVL1 Role in Cell Fusion and Tunneling Membrane Nanotube Formations with Implication to Treat Glioma Heterogeneity by Filippova, Natalia, Nabors, Louis B.

“…Homotypic and heterotypic cell fusions via permanent membrane fusions and temporal tunneling nanotube formations in the glioma microenvironment were recently…”
Get full text

The versatile role of HuR in Glioblastoma and its potential as a therapeutic target for a multi-pronged attack by Guha, Abhishek, Waris, Saboora, Nabors, Louis B., Filippova, Natalia, Gorospe, Myriam, Kwan, Thaddaeus, King, Peter H.

“…[Display omitted] Glioblastoma (GBM) is a malignant and aggressive brain tumor with a median survival of ∼15 months. Resistance to treatment arises from the…”
Get full text

Hu antigen R (HuR) multimerization contributes to glioma disease progression by Filippova, Natalia, Yang, Xiuhua, Ananthan, Subramaniam, Sorochinsky, Anastasia, Hackney, James R., Gentry, Zachery, Bae, Sejong, King, Peter, Nabors, L. Burt

“…Among primary brain cancers, gliomas are the most deadly and most refractory to current treatment modalities. Previous reports overwhelmingly support the role…”
Get full text

IN MEMORIAM: YURI SERGEEVICH BALASHOV: 25 December 1931-28 September 2012 by Filippova, Natalia A

Get full text

Abstract 3335: Characterization and analysis of the complement immune system in glioblastoma (GBM) by Hayward, Emily Nicole, Yang, Xiuhua, Filippova, Natalia, Calano, Jennifer A., Namkoong, David, Kovac, Stefan, Nabors, Louis B.

“…Abstract The purpose of this study is to determine the role of the complement immune system in glioma and/or glioma therapy. Glioblastoma (GBM) is the most…”
Get full text

SRI‐42127, a novel small molecule inhibitor of the RNA regulator HuR, potently attenuates glial activation in a model of lipopolysaccharide‐induced neuroinflammation by Chellappan, Rajeshwari, Guha, Abhishek, Si, Ying, Kwan, Thaddaeus, Nabors, Louis B., Filippova, Natalia, Yang, Xiuhua, Myneni, Anish S., Meesala, Shriya, Harms, Ashley S., King, Peter H.

“…Glial activation with the production of pro‐inflammatory mediators is a major driver of disease progression in neurological processes ranging from acute…”
Get full text

RNA regulation of inflammatory responses in glia and its potential as a therapeutic target in central nervous system disorders by Guha, Abhishek, Husain, Mohammed Amir, Si, Ying, Nabors, L. Burt, Filippova, Natalia, Promer, Grace, Smith, Reed, King, Peter H.

“…A major hallmark of neuroinflammation is the activation of microglia and astrocytes with the induction of inflammatory mediators such as IL‐1β, TNF‐α, iNOS,…”
Get full text

Targeting the HuR Oncogenic Role with a New Class of Cytoplasmic Dimerization Inhibitors by Filippova, Natalia, Yang, Xiuhua, Ananthan, Subramaniam, Calano, Jennifer, Pathak, Vibha, Bratton, Larry, Vekariya, Rakesh H, Zhang, Sixue, Ofori, Edward, Hayward, Emily N, Namkoong, David, Crossman, David K, Crowley, Michael R, King, Peter H, Mobley, James, Nabors, Louis B

“…The development of novel therapeutics that exploit alterations in the activation state of key cellular signaling pathways due to mutations in upstream…”
Get full text

Inhibition of the RNA Regulator HuR by SRI-42127 Attenuates Neuropathic Pain After Nerve Injury Through Suppression of Neuroinflammatory Responses by Sorge, Robert E., Si, Ying, Norian, Lyse A., Guha, Abhishek, Moore, Grace E., Nabors, L. Burt, Filippova, Natalia, Yang, Xiuhua, Smith, Reed, Chellappan, Rajeshwari, King, Peter H.

“…Microglial activation with the production of pro-inflammatory mediators such as IL-6, TNF-α, and IL-1β, is a major driver of neuropathic pain (NP) following…”
Get full text

The role of Src family kinases in growth and migration of glioma stem cells by HAN, XIAOSI, ZHANG, WENBIN, YANG, XIUHUA, WHEELER, CRYSTAL G, LANGFORD, CATHERINE P, WU, LU, FILIPPOVA, NATALIA, FRIEDMAN, GREGORY K, DING, QIANG, FATHALLAH-SHAYKH, HASSAN M, GILLESPIE, G. YANCEY, NABORS, L. BURT

“…Src family kinases (SFKs) are highly expressed and active in clinical glioblastoma multiforme (GBM) specimens. SFKs inhibitors have been demonstrated to…”
Get full text

Constitutionalization of National Minority Rights in BRICS Countries (Brazil, India and Russia) by Kumar, A., Rudenko, V., Filippova, N.

“…On the basis of comparative law, this paper analyzes the issues of national minorities in three BRICS member-states (Brazil, India and Russia), and considers…”
Get full text