Search Results - "Filippidou, Natalia"

Rapalog resistance is associated with mesenchymal-type changes in Tsc2-null cells by Valianou, Matthildi, Filippidou, Natalia, Johnson, Daniel L., Vogel, Peter, Zhang, Erik Y., Liu, Xiaolei, Lu, Yiyang, Yu, Jane J., Bissler, John J., Astrinidis, Aristotelis

“…Tuberous Sclerosis Complex (TSC) and Lymphangioleiomyomatosis (LAM) are caused by inactivating mutations in TSC1 or TSC2 , leading to mTORC1 hyperactivation…”
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Mechanisms of activation induced by antiphospholipid antibodies in multiple sclerosis: Potential biomarkers of disease? by Filippidou, Natalia, Krashias, George, Christodoulou, Christina, Pantzaris, Marios, Lambrianides, Anastasia

“…Multiple sclerosis (MS) is a chronic, multifactorial, inflammatory disease of the central nervous system where demyelination leads to neurodegeneration and…”
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Abstract 3022: Dissecting rapamycin resistance in a Tsc2-null rat leiomyoma cell line developed in a murine xenograft by Filippidou, Natalia, Valianou, Mathildi, Johnson, Daniel L., Bissler, John J., Astrinidis, Aristotelis

“…Despite the identification of mTOR hyperactivation as the main biochemical defect downstream of TSC1/TSC2 inactivation in Lymphangioleiomyomatosis (LAM) and…”
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Exploration of isatin-based inhibitors of SARS-CoV-2 Nsp15 endoribonuclease by Rampias, Theodoros, Antoniou, Thomas, Stevaert, Annelies, Kravariti, Lara, Van Loy, Benjamin, Vandeput, Julie, Sgrignani, Jacopo, Filippidou, Natalia, Locatelli, Patrizia, Samiotaki, Martina, Tzakos, Eleftherios Paraskevas, Cavalli, Andrea, Naesens, Lieve, Sideris, Diamantis C., Tzakos, Andreas G.

“…The global health crisis caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) urges the development of new antiviral agents with broad…”
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The possible role of an autoimmune mechanism in the etiopathogenesis of Parkinson’s disease by Dalitis, Savvas, Filippidou, Natalia, Krashias, George, Christodoulou, Christina, Pantzaris, Marios, Lambrianides, Anastasia

“…•Anti-PS and anti-dsDNA antibodies were elevated in PD patients.•The presence of these autoantibodies is not analogous with increased levels of oxidative…”
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The association between IgG and IgM antibodies against cardiolipin, β2-glycoprotein I and Domain I of β2-glycoprotein I with disease profile in patients with multiple sclerosis by Filippidou, Natalia, Krashias, George, Pericleous, Charis, Rahman, Anisur, Ioannou, Yiannis, Giles, Ian, Demetriou, Christiana, Anatolitou, Afroditi, Christodoulou, Christina, Pantzaris, Marios, Lambrianides, Anastasia

“…•First study to identify anti-domain I antibodies in multiple sclerosis patients.•Anti-cardiolipin antibodies were raised in secondary progressive multiple…”
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The association between IgG and IgM antibodies against cardiolipin, beta 2-glycoprotein I and Domain I of beta 2-glycoprotein I with disease profile in patients with multiple sclerosis by Filippidoua, Natalia, Krashiasa, George, Pericleousb, Charis, Rahmanb, Anisur, Ioannoub, Yiannis, Gilesb, Ian, Demetrioua, Christiana, Anatolitoua, Afroditi, Christodouloua, Christina, Pantzarisa, Marios, Lambrianidesa, Anastasia

“…Antiphospholipid antibodies (aPL) occur in patients with multiple sclerosis (MS) with a number of studies reporting elevated levels; their exact prevalence and…”
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