Search Results - "Filipowicz, Adam R."
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Dysregulation of sonic hedgehog pathway and pericytes in the brain after lentiviral infection
Published in Journal of neuroinflammation (13-04-2019)“…Impairment of the blood-brain barrier (BBB) has been associated with cognitive decline in many CNS diseases, including HIV-associated neurocognitive disorders…”
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Lentiviral infection of proliferating brain macrophages in HIV and simian immunodeficiency virus encephalitis despite sterile alpha motif and histidine-aspartate domain-containing protein 1 expression
Published in AIDS (London) (15-05-2018)“…OBJECTIVE:HIV-1 infection of the brain and related cognitive impairment remain prevalent in HIV-1-infected individuals despite combination antiretroviral…”
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Atherosclerosis-Driven Treg Plasticity Results in Formation of a Dysfunctional Subset of Plastic IFNγ+ Th1/Tregs
Published in Circulation research (11-11-2016)“…RATIONALE:Forkhead box P3 T regulatory cells (Tregs) are key players in maintaining immune homeostasis. Evidence suggests that Tregs respond to environmental…”
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Proliferation of Perivascular Macrophages Contributes to the Development of Encephalitic Lesions in HIV-Infected Humans and in SIV-Infected Macaques
Published in Scientific reports (09-09-2016)“…The aim of the present study was to investigate if macrophage proliferation occurs in the brain during simian immunodeficiency virus (SIV) infection of adult…”
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Increased Expression of CD169 on Blood Monocytes and Its Regulation by Virus and CD8 T Cells in Macaque Models of HIV Infection and AIDS
Published in AIDS research and human retroviruses (01-07-2015)“…Increased expression of CD169 on monocytes has been reported in HIV-1-infected humans. Using rhesus macaque models of HIV infection, we sought to investigate…”
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Lentiviral infection of proliferating brain macrophages in SIV and HIV encephalitis despite SAMHD1 expression
Published in AIDS (London) (15-03-2018)“…OBJECTIVE:HIV-1 infection of the brain and related cognitive impairment remain prevalent in HIV-1-infected subjects despite combination antiretroviral therapy…”
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Abstract 350: The Pro-atherosclerotic Milieu Converts a Sub-population of Murine Peripheral T Regulatory Cells to a Non-suppressive Th1-like Foxp3+IFNγ+ Phenotype
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2015)“…Abstract only CD4+ T cell subsets play diverse roles in inflammation but may also display limited plasticity. The existence of a population of Foxp3+ T…”
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Abstract 447: Atherosclerosis-driven Treg Plasticity Results in the Formation of a Dysfunctional Subset of Plastic IFNg + Th1/Tregs
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2016)“…Abstract only Foxp3 + T regulatory cells (Tregs) are key players in maintaining immune homeostasis. Emerging evidence suggests that Tregs respond to…”
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