Search Results - "Filipenko, M."
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1
Biodegradation of polyhydroxyalkanoates (PHAs) in tropical coastal waters and identification of PHA-degrading bacteria
Published in Polymer degradation and stability (01-12-2010)“…Biodegradability patterns of two PHAs: a polymer of 3-hydroxybutyric acid (3-PHB) and a copolymer of 3-hydroxybutyric and 3-hydroxyvaleric acids (3-PHB/3-PHV)…”
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Circular RNA: New Regulatory Molecules
Published in Bulletin of experimental biology and medicine (01-04-2018)“…Circular RNA are a family of covalently closed circular RNA molecules, formed from pre-mRNA of coding genes by means of splicing (canonical and alternative…”
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3
Development of a Cell Line Containing the Chimeric ETV6-NTRK3 Gene. The Search for Mutations of the Tyrosine Kinase Chimeric Domain That Cause Resistance to Larotrectinib
Published in Bulletin of experimental biology and medicine (01-05-2023)“…The development, registration, and further use of entrectinib and larotrectinib for the treatment of tumors resulting from oncogenic stimulation of chimeric…”
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4
Mutations in the pncA and rpsA genes among 77 Mycobacterium tuberculosis isolates in Kazakhstan
Published in The international journal of tuberculosis and lung disease (01-02-2015)“…SETTING: Pyrazinamide (PZA), an important first-line drug for anti-tuberculosis treatment, demonstrates potent activity against semi-dormant bacilli in acidic…”
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5
Identification of Chimeric NTRK3 Genes in Papillary Thyroid Cancer Cells by Analyzing the Imbalance of the Expression of 5’ and 3’ mRNA Fragments
Published in Bulletin of experimental biology and medicine (01-06-2023)“…The standard for detecting chimeric genes of neurotrophic receptor tyrosine kinases ( NTRK ) is next generation sequencing (NGS). However, this analysis is…”
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Evaluation of Advantages of Lithium Chloride as a Precipitating Agent in RNA Isolation from Frozen Vein Segments
Published in Bulletin of experimental biology and medicine (01-07-2022)“…Contamination of the sample with DNA is a problem when isolating RNA by phenol-chloroform extraction, and DNase treatment introduces an additional error in the…”
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Differences in Transcriptomic Profiles of Brain and Thyroid Tumors with NTRK Gene Rearrangement
Published in Bulletin of experimental biology and medicine (01-05-2023)“…For tumors with chimeric NTRK genes, entrectinib and larotrectinib can be prescribed regardless of tumor localization. We compared changes in the…”
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8
Polymorphisms of genes involved in inflammation and blood vessel development influence the risk of varicose veins
Published in Clinical genetics (01-08-2018)“…Heredity plays an important role in the etiology of varicose veins (VVs). However, the genetic basis underlying this condition remains poorly understood. Our…”
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The Level of LINE-1 mRNA Is Increased in Extracellular Circulating Plasma RNA in Patients with Colorectal Cancer
Published in Bulletin of experimental biology and medicine (01-06-2022)“…We performed a comparative quantitative analysis of LINE-1 mRNA levels in extracellular total plasma RNA in patients with colon cancer and practically healthy…”
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Prediction of EVT6-NTRK3-Dependent Papillary Thyroid Cancer Using Minor Expression Profile
Published in Bulletin of experimental biology and medicine (01-06-2022)“…Solid tumors resulting from oncogenic stimulation of neurotrophin receptors (TRK) by chimeric proteins are a group of rare tumors of various localization that…”
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11
Genetic basis of individual treatment response to disease modifying drugs in multiple sclerosis patients
Published in Journal of the neurological sciences (15-10-2015)Get full text
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12
Increased Frequencies of the ‒174G and ‒572C IL6 Alleles in Populations of Indigenous Peoples of Siberia Compared to Russians
Published in Molecular biology (New York) (2023)“…—The study of immune response and inflammation gene polymorphisms in a genogeographic context is relevant in the study of human populations. Here, in the…”
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Development of a Test System to Detect the Omicron Variant of SARS-CoV-2 and the Frequency of Its Detection in Patients
Published in Bulletin of experimental biology and medicine (01-06-2022)“…We developed a new test system to detect the omicron variant of SARS-CoV-2 using allele-specific reverse transcription PCR and estimated the frequency of its…”
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14
Biodegradation of polyhydroxyalkanoates by soil microbial communities of different structures and detection of PHA degrading microorganisms
Published in Applied biochemistry and microbiology (01-01-2012)“…Biodegradation of microbial linear polymers of hydroxyalkanoic acids (polyhydroxyalkanoates, PHAs) by soil microbial communities of different structures has…”
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15
Mitochondrial DNA analysis of ancient sheep from Altai
Published in Animal genetics (01-10-2017)“…Summary A comparative analysis of the genetic diversity of ancient and modern sheep can shed light on the origin of these animals and their distribution as…”
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Correction to: Polymorphisms of genes involved in inflammation and blood vessel development influence the risk of varicose veins
Published in Clinical genetics (01-11-2018)Get full text
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DNA-Binding Domain of DNA Ligase from the Thermophilic Archaeon Pyrococcus abyssi: Improving Long-Range PCR and Neutralization of Heparin’s Inhibitory Effect
Published in Applied biochemistry and biotechnology (01-08-2015)“…The DNA-binding domain of the DNA ligase from Pyrococcus abyssi (PabDBD) was mapped and cloned into two expression vectors. The resulting 6X His-tagged…”
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Elimination of DNA Multimerization Arising from Isothermal Amplification in the Presence of Bst Exo– DNA Polymerase
Published in Russian journal of bioorganic chemistry (2020)“…In recent years, methods of isothermal amplification of nucleic acids using polymerases with a strand-displacement activity have become widespread for…”
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Soluble Ligand of the Immune Checkpoint Receptor (sPD-L1) in Blood Serum of Patients with Renal Cell Carcinoma
Published in Bulletin of experimental biology and medicine (01-01-2019)“…The content of the soluble ligand of the immune checkpoint receptor (sPD-L1) was determined in the blood serum of 106 patients with renal cell carcinoma and 11…”
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TCF7L2 gene polymorphism in populations of f ive Siberian ethnic groups
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (01-03-2022)“…Investigation of the frequencies of functionally signif icant gene variants in the context of medical biology and gene geography is a relevant issue for…”
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